Blar i St. Olavs hospital på tittel

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    • Discrimination of Breast Cancer from Healthy Breast Tissue Using a Three-component Diffusion-weighted MRI Model 

      Andreassen, Maren Marie Sjaastad; Rodriguez-Soto, Ana; Conlin, CC; Vidić, I; Seibert, TM; Wallace, AM; Zare, S; Kuperman, J; Abudu, B; Ahn, GS; Hahn, M; Jerome, Neil Peter; Østlie, Agnes; Bathen, Tone Frost; Ojeda-Fournier, H; Goa, Pål Erik; Rakow-Penner, Rebecca; Dale, AM (Peer reviewed; Journal article, 2020)
      Purpose: Diffusion-weighted MRI (DW-MRI) is a contrast-free modality that has demonstrated ability to discriminate between predefined benign and malignant breast lesions. However, how well DW-MRI discriminates cancer from ...

    • Disease-associated reference intervals for twenty laboratory tests in patients with rheumatoid arthritis, Crohn's disease or ulcerative colitis 

      Mikkelsen, Gustav; Lillebo, Børge; Faxvaag, Arild (Peer reviewed; Journal article, 2021)
      Background Population based reference intervals are fundamental for interpreting results for quantitative laboratory tests. In patients with a specific chronic disorder, however, results of various tests may regularly be ...

    • Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors 

      Mullins, Niamh; Kang, JooEun; Campos, Adrian I.; Coleman, Jonathan R.I.; Edwards, Alexis C.; Galfalvy, Hanga; Levey, Daniel F.; Lori, Adriana; Shabalin, Andrey A; Andreassen, Ole; Melle, Ingrid; Morken, Gunnar; Starnawska, Anna; Su, Mei-Hsin; Watson, Hunna J; Adams, Mark; Awasthi, Swapnil; Gandal, Michael; Hafferty, Jonathan; Hishimoto, Akitoyo; Kim, Minsoo; Okazaki, Satoshi; Otsuka, Ikuo; Ware, Erin B.; Stephan, Ripke; Bergen, Andrew W.; Berrettini, Wade H.; Bohus, Martin; Brandt, Harry; Chang, Xiao; Chen, Wei J; Chen, Hsi-Chung; Crawford, Steven; Crow, Scott; DiBlasi, Emily; Duriez, Philibert; Fichter, Manfred M; Fernández-Aranda, Fernando; Gallinger, Steven; Glatt, Stephen J.; Gorwood, Philip; Guo, Yiran; Hakonarson, Hakon; Halmi, Katherine A; Hwu, Hai-Gwo; Jain, Sonia; Jamain, Stephane; Jimenez-Murcia, Susana; Johnson, Craig; Djurovic, Srdjan (Peer reviewed; Journal article, 2022)
      Background Suicide is a leading cause of death worldwide, and nonfatal suicide attempts, which occur far more frequently, are a major source of disability and social and economic burden. Both have substantial genetic ...

    • Distinct interferon signatures and cytokine patterns define additional systemic autoinflammatory diseases. 

      de Jesus, Adriana Almeida; Hou, Yangfeng; Brooks, Stephen; Malle, Louise; Biancotto, Angelique; Huang, Yan; Calvo, Katherine R.; Marrero, Bernadette; Moir, Susan; Oler, Andrew J.; Deng, Zuoming; Sanchez, Gina A. Montealegre; Ahmed, Amina; Allenspach, Eric; Srabshahi, Bita; Behrens, Edward M.; Benseler, Susanne; Berzrodnik, Liliana; Bout-Tabaku, Sharon; Brescia, AnneMarie; Brown, Diane; Burnham, Jon M.; Caldirola, Maria Soledad; Carrasco, Ruy; Chan, Alice; Cimaz, Rolando; Dancey, Paul; Dare, Jason; DeGuzman, Marietta; Dimitriades, Victoria; Ferguson, Ian; Ferguson, Polly J.; Finn, Laura; Gattorno, Marco; Grom, Alexei; Hanson, Eric P.; Hashkes, Philip; Hedrich, Christian M.; Herzog, Ronit; Horneff, Gerd; Jerath, Rita; Kessler, Elizabeth; Kim, Hanna; Kingsbury, Daniel J.; Laxer, Ronald M; Lee, Pui Y.; Lee-Kirsch, Min Ae; Lewandowski, Laura; Li, Suzanne; Lilleby, Vibke; Mammadova, Vafa; Moorthy, Lakshmi N.; Nasrullayeva, Gulnara M.; O'Neill, Kathleen; Onel, Karen; Ozen, Seza; Pan, Nancy; Pillet, Pascal; Piotto, Daniela G. P.; Punaro, Marilynn G.; Reiff, Andreas; Reinhardt, Adam L.; Rider, Lisa G.; Rivas-Chacon, Rafael; Ronis, Tova; Rosen-Wolff, Angela; Roth, Johannes; Ruth, Natasha Mckerran; Rygg, Marite; Schmeling, Heinrike; Schulert, Grant; Scott, Christiaan; Seminario, Gisella; Schulman, Andrew; Sivaraman, Vidya; Son, Mary Beth; Stepanovskiy, Yuriy; Stringer, Elizabeth; Taber, Sara; Terreri, Maria Teresa; Tifft, Cynthia J; Torgerson, Troy R.; Tosi, Laura; Royen-Kerkhof, Annet Van; Muskardin, Theresa Wampler; Canna, Scott W.; Goldbach-Mansky, Raphaela (Peer reviewed; Journal article, 2020)
      BACKGROUND. Undifferentiated systemic autoinflammatory diseases (USAIDs) present diagnostic and therapeutic challenges. Chronic interferon (IFN) signaling and cytokine dysregulation may identify diseases with available ...

    • Distinguishing sleep from wake with a radar sensor: A contact-free real-time sleep monitor 

      Heglum, Hanne Siri Amdahl; Kallestad, Håvard; Vethe, Daniel; Langsrud, Knut; Sand, Trond; Engstrøm, Morten (Journal article; Peer reviewed, 2021)
      This work aimed to evaluate whether a radar sensor can distinguish sleep from wakefulness in real time. The sensor detects body movements without direct physical contact with the subject and can be embedded in the roof of ...

    • Divergent Regulation of Decidual Oxidative-Stress Response by NRF2 and KEAP1 in Preeclampsia with and without Fetal Growth Restriction 

      Mundal, Siv Boon; Rakner, Johanne Johnsen; Silva, Gabriela; Gierman, Lobke; Austdal, Marie; Basnet, Purusotam; Elschot, Mattijs; Bakke, Siril Skaret; Ostrop, Jenny; Thomsen, Liv Cecilie Vestrheim; Moses, Eric; Acharya, Ganesh; Bjørge, Line; Iversen, Ann-Charlotte (Peer reviewed; Journal article, 2022)
      Utero-placental development in pregnancy depends on direct maternal–fetal interaction in the uterine wall decidua. Abnormal uterine vascular remodeling preceding placental oxidative stress and placental dysfunction are ...

    • DNA glycosylase Neil2 contributes to genomic responses in the spleen during clinical prion disease 

      Scheffler, Katja; Jalland, Clara Maria Osnes; Benestad, Sylvie L.; Moldal, Torfinn; Ersdal, Cecilie; Gunnes, Gjermund; Suganthan, Rajikala; Bjørås, Magnar; Tranulis, Michael A. (Peer reviewed; Journal article, 2020)
      The DNA glycosylase Neil2 is a member of the base excision repair (BER) family of enzymes, which are important for repair of oxidative DNA damage. Specifically, Neil2 participates in repair of oxidized bases in single-stranded ...

    • DNA Methylation Adds Prognostic Value to Minimal Residual Disease Status in Pediatric T-Cell Acute Lymphoblastic Leukemia 

      Borssén, Magnus; Haider, Zahra; Landfors, Mattias; Norén-Nyström, Ulrika; Schmiegelow, Kjeld; Åsberg, Ann Elisabeth; Kanerva, Jukka; Madsen, Hans O.; Marquart, Hanne; Heyman, Mats; Hultdin, Magnus; Roos, Göran; Forestier, Erik; Degerman, Sofie (Peer reviewed; Journal article, 2016)
      Background. Despite increased knowledge about genetic aberrations in pediatric T-cell acute lymphoblastic leukemia (T-ALL), no clinically feasible treatment-stratifying marker exists at diagnosis. Instead patients are ...

    • DNA methylation changes in response to neoadjuvant chemotherapy are associated with breast cancer survival 

      Pedersen, Christine Aaserød; Cao, Maria Dung; Fleischer, Thomas; Rye, Morten Beck; Knappskog, Stian; Eikesdal, Hans Petter; Lønning, Per Eystein; Tost, Jörg; Kristensen, Vessela N.; Tessem, May-Britt; Giskeødegård, Guro F.; Bathen, Tone Frost (Peer reviewed; Journal article, 2022)
      Background Locally advanced breast cancer is a heterogeneous disease with respect to response to neoadjuvant chemotherapy (NACT) and survival. It is currently not possible to accurately predict who will benefit from the ...

    • DNA methylation profiling for molecular classification of adult diffuse lower-grade gliomas 

      Ferreyra Vega, Sandra; Olsson Bontell, Thomas; Corell, Alba; Smits, Anja; Jakola, Asgeir Store; Carén, Helena (Peer reviewed; Journal article, 2021)
      Background - DNA methylation profiling has facilitated and improved the classification of a wide variety of tumors of the central nervous system. In this study, we investigated the potential utility of DNA methylation ...

    • DNA methylation-based age acceleration observed in IDH wild-type glioblastoma is associated with better outcome-including in elderly patients 

      Bady, Pierre; Marosi, Christine; Weller, Michael; Grønberg, Bjørn Henning; Schultz, Henrik; Taphoorn, Martin J B; Gijtenbeek, Johanna M M; van den Bent, Martin J.; von Deimling, Andreas; Stupp, Roger; Malmström, Annika; Hegi, Monika E. (Peer reviewed; Journal article, 2022)
      Elderly patients represent a growing proportion of individuals with glioblastoma, who however, are often excluded from clinical trials owing to poor expected prognosis. We aimed at identifying age-related molecular differences ...

    • Do Breast Cancer Patients Manage to Participate in an Outdoor, Tailored, Physical Activity Program during Adjuvant Breast Cancer Treatment, Independent of Health and Socio-Demographic Characteristics? 

      Stalsberg, Ragna; Bertheussen, Gro Falkener; Børset, Harriet; Thomsen, Simon Nørskov; Husøy, Anders; Flote, Vidar Gordon; Thune, Inger; Lundgren, Steinar (Peer reviewed; Journal article, 2022)
      Exercise could reduce the side-effects of adjuvant breast cancer treatment; however, socio-demographic, health, and intervention conditions may affect patients’ adherence to interventions. This study aimed to examine ...

    • Do Childhood Boarding School Experiences Predict Health, Well-Being and Disability Pension in Adults? A SAMINOR Study 

      Friborg, Oddgeir; Sørlie, Tore; Schei, Berit; Javo, Cecilie; Sørbye, Øystein; Hansen, Ketil Lenert (Peer reviewed; Journal article, 2020)
      Indigenous Sámi and Kven minority children in Norway were during the 20th century placed at boarding schools to hasten their adoption of the Norwegian majority language and culture. This is the first population-based study ...

    • Do differences in diagnostic criteria for late fetal growth restriction matter? 

      Mylrea-Foley, Bronacha; Napolitano, Raffaele; Gordijn, Sanne; Wolf, Hans; Lees, Christoph C.; Stampalija, Tamara; Arabin, B.; Berger, A.; Bergman, E.; Bhide, A; Bilardo, C.M.; Breeze, A.C.; Brodszki, J.; Calda, P.; Cesari, E.; Cetin, I.; Derks, J.; Ebbing, Cathrine; Ferrazzi, E.; Frusca, T.; Ganzevoort, W.; Gyselaers, W.; Hecher, K.; Klaritsch, P.; Krofta, L.; Lindgren, P.; Lobmaier, S.M.; Marlow, N.; Maruotti, G.M.; Mecacci, F.; Myklestad, Kirsti; Prefumo, F.; Raio, L.; Richter, J.; Sande, Ragnar; Valensise, H.; Visser, G.H.A.; Wee, L. (Peer reviewed; Journal article, 2023)
      BACKGROUND Criteria for diagnosis of fetal growth restriction differ widely according to national and international guidelines, and further heterogeneity arises from the use of different biometric and Doppler reference ...

    • Do Gastric Signet Ring Cell Carcinomas and ECL‐Cell Neuroendocrine Tumours Have a Common Origin? 

      Fossmark, Reidar; Johannessen, Rune; Qvigstad, Gunnar; Mjønes, Patricia (Peer reviewed; Journal article, 2022)
      Gastric cancer is a heterogenous group of tumours, and a better understanding of the carcinogenesis and cellular origin of the various sub-types could affect prevention and future treatment. Gastric neuroendocrine tumours ...

    • Do Norwegians with diabetes have a healthier diet than the general population? 

      Aas, Anne-Marie; Johansson, Lars; Bjerkan, Kirsti; Lorentsen, Nina; Mostad, Ingrid Løvold (Journal article; Peer reviewed, 2013)
      Objective: Review current knowledge about dietary habits among people with diabetes in Norway compared with the general population and nutrient- and food-based dietary recommendations. Method: Baseline dietary data from ...

    • Do patients with gastroesophageal reflux disease exhibit compromised bone quality prior to proton pump inhibitor therapy? 

      Aasarød, Kristin Matre; Mosti, Mats Peder; Finstad, Malin T.; Stunes, Astrid Kamilla; Fossmark, Reidar; Syversen, Unni (Peer reviewed; Journal article, 2021)
      Patients with gastroesophageal reflux disease (GERD) are routinely treated with proton pump inhibitors (PPIs), despite many reports of increased fracture risk associated with PPI use. Notably, the skeletal properties in ...

    • Do Various Respirator Models Fit the Workers in the Norwegian Smelting Industry? 

      Føreland, Solveig; Robertsen, Øystein; Hegseth, Marit Nøst (Journal article; Peer reviewed, 2019)
      Background Respirator fit testing is a method to assess if the respirator provides an adequate face seal for the worker. Methods Workers from four Norwegian smelters were invited to participate in the study, and 701 ...

    • Does a history of cardiovascular disease or cancer affect mortality after SARS-CoV-2 infection? 

      Kvåle, Rune; Bønaa, Kaare Harald; Forster, Rachel Bedenis; Gravningen, Kirsten Midttun; Juliusson, Pétur Benedikt; Myklebust, Tor Åge (Peer reviewed; Journal article, 2021)
      BAKGRUNN Hjerte- og karsykdommer og kreft har vært beskrevet som mulige risikofaktorer for død av covid-19. Hensikten med studien er å undersøke om tidligere påvist hjerte- og karsykdom eller kreft har påvirket risiko for ...

    • Does caesarean delivery in the first pregnancy increase the risk for adverse outcome in the second? A registry-based cohort study on first and second singleton births in Norway 

      Bjellmo, Solveig; Andersen, Guro Lillemoen; Hjelle, Sissel; Klungsøyr, Kari; Krebs, Lone; Lydersen, Stian; Romundstad, Pål Richard; Vik, Torstein (Peer reviewed; Journal article, 2020)
      Objective To explore if newborns in the second pregnancy following a previous caesarean delivery (CD) have higher risk of perinatal mortality or cerebral palsy than newborns in pregnancies following a previous vaginal ...