Browsing St. Olavs hospital by Title

Now showing items 508-527 of 2440

    • Depression trajectories and cytokines in schizophrenia spectrum disorders - A longitudinal observational study 

      Hoprekstad, Gunnhild Eldhuset; Kjelby, Eirik; Gjestad, Rolf; Fathian, Farivar; Larsen, Tor Ketil; Reitan, Solveig Klæbo; Rettenbacher, Maria; Torsvik, Anja; Skrede, Silje; Johnsen, Erik; Kroken, Rune Andreas (Peer reviewed; Journal article, 2023)
      Depression occurs frequently in all phases of schizophrenia spectrum disorders. Altered activity in the immune system is seen in both depression and schizophrenia. We aimed to uncover depressive trajectories in a sample ...

    • Depression, Anxiety, Insomnia, and Quality of Life in a Representative Community Sample of Older Adults Living at Home 

      Kennair, Leif Edward Ottesen; Hagen, Roger; Hjemdal, Odin; Havnen, Audun; Ryum, Truls; Solem, Stian (Peer reviewed; Journal article, 2022)
      Background: The aim of the study was to explore symptoms of anxiety and depression, insomnia, and quality of life in a Norwegian community sample of older adults. Methods: A representative sample (N = 1069) was drawn ...

    • Descent of fetal head during active pushing: secondary analysis of prospective cohort study investigating ultrasound examination before operative vaginal delivery 

      Kahrs, Birgitte Heiberg; Usman, Sana; Ghi, T; Youssef, A; Torkildsen, Erik A.; Lindtjørn, Elsa; Østborg, Tilde Broch; Benediktsdóttir, Sigurlaug; Brooks, L; Harmsen, Lotte; Salvesen, Kjell Å; Lees, C; Eggebø, Torbjørn Moe (Peer reviewed; Journal article, 2019)
      Objectives To investigate if descent of the fetal head during active pushing is associated with duration of operative vaginal delivery, mode of delivery and neonatal outcome in nulliparous women with prolonged second stage ...

    • Descent of the presenting part assessed with ultrasound 

      Eggebø, Torbjørn Moe; Hjartardottir, Hulda (Peer reviewed; Journal article, 2021)
      Fetal head descent can be expressed as fetal station and engagement. Station is traditionally based on clinical vaginal examination of the distal part of the fetal skull and related to the level of the ischial spines. ...

    • Description of the prehospital emergency healthcare system in Norway 

      Kjærvoll, Hege K.; Andersson, Lars-Jøran; Bakkelund, Karin Elvenes; Harring, Astrid Karina V.; Tjelmeland Myrhaugen, Ingvild Beathe (Peer reviewed; Journal article, 2024)
      Background: Norway has a long coastline, steep mountains, and wide fjords, which presents some challenges to the prehospital emergency healthcare system. In recent years, the prehospital emergency medical services (EMS) ...

    • Desflurane consumption with automated vapour control systems in two different anaesthesia machines. A randomized controlled study 

      Mostad, Dagmar; Klepstad, Pål; Follestad, Turid; Pleym, Hilde (Peer reviewed; Journal article, 2021)
      Background: In general anaesthesia practice a fresh gas flow (FGF) of ≥0.5 L/min is usually applied. Automated gas delivery devices are developed to reduce volatile anaesthetic consumption by limiting gas flow. This study ...

    • Design, Development, and Evaluation of an mHealth App for Reporting of Side Effects During Cytostatic Treatment: Usability Test and Interview Study 

      Hægermark , Emil Carl Richard Aale ; Kongshaug, Nina Anita; Raj, Sunil Xavier; Hofsli, Eva; Faxvaag, Arild (Peer reviewed; Journal article, 2023)
      Background: Using mobile health (mHealth) interventions such as smartphone apps to deliver health services is an opportunity to engage patients more actively in their own treatment. Usability tests allow for the evaluation ...

    • Designing Serious Games for Cyber Ranges: A Socio-technical Approach 

      Kianpour, Mazaher; Kowalski, Stewart James; Zoto, Erjon; Frantz, Christopher; Øverby, Harald (Chapter, 2019)
      Appropriate training is an effective solution to tackle the evolving threat landscape and conflicts in the cyber domain and to fulfill security requirements. Serious games demonstrate pedagogic effectiveness in this field, ...

    • Detailed stratified GWAS analysis for severe COVID-19 in four European populations 

      Degenhardt, Frauke; Ellinghaus, David; Juzenas, Simonas; Lerga-Jaso, Jon; Wendorff, Mareike; Maya-Miles, Douglas; Uellendahl-Werth, Florian; ElAbd, Hesham; Lenning, Ole Bernt; Myhre, Ronny; Vadla, May Sissel; Holten, Aleksander Rygh; Kildal, Anders Benjamin; Lind, Andreas; Dyrhol-Riise, Anne Ma; Hoff, Dag Arne Lihaug; Müller, Fredrik; Solligård, Erik; Holter, Jan Cato; Afset, Jan Egil; Damås, Jan Kristian; Bergan, Jonas; Risnes, Kari; Muller, Karl Erik; Tonby, Kristian; Heggelund, Lars; Gustad, Lise Tuset; Grimsrud, Marit Mæhle; Dudman, Susanne Gjeruldsen; Folseraas, Trine; Skogen, Vegard; Hov, Johannes Espolin Roksund; Karlsen, Tom Hemming; Rühlemann, Malte C.; Arora, Jatin; Özer, Onur; Wacker, Eike Matthias; Wienbrandt, Lars; Ortiz, Aron Blandino; de Salazar, Adolfo; Chercoles, Adolfo Garrido; Palom, Adriana; Ruiz, Agustin; Garzia-Fernandez, Alba-Estela; Blanco-Grau, Albert; Mantovani, Alberto; Zanella, Alberto; Mayer, Alena; Bandera, Alessandra; Franke, Andre (Peer reviewed; Journal article, 2022)
      Given the highly variable clinical phenotype of Coronavirus disease 2019 (COVID-19), a deeper analysis of the host genetic contribution to severe COVID-19 is important to improve our understanding of underlying disease ...

    • Detecting copy number variation in next generation sequencing data from diagnostic gene panels 

      Singh, Ashish Kumar; Olsen, Maren Fridtjofsen; Lavik, Liss Ane; Vold, Trine; Drabløs, Finn; Sjursen, Wenche (Peer reviewed; Journal article, 2021)
      Background Detection of copy number variation (CNV) in genes associated with disease is important in genetic diagnostics, and next generation sequencing (NGS) technology provides data that can be used for CNV detection. ...

    • Detection of Cerebral High-Intensity Transient Signals by NeoDoppler during Cardiac Catheterization and Cardiac Surgery in Infants 

      Leth-Olsen, Martin; Døhlen, Gaute; Torp, Hans; Nyrnes, Siri Ann (Peer reviewed; Journal article, 2022)
      There is a risk of gaseous and solid micro-embolus formation during transcatheter cardiac interventions and surgery in children with congenital heart disease (CHD). Our aim was to study the burden of high-intensity transient ...

    • Detection of germline variants with pathogenic potential in 48 patients with familial colorectal cancer by using whole exome sequencing 

      Singh, Ashish Kumar; Talseth-Palmer, Bente Anita; Xavier, Alexandre; Scott, Rodney J.; Drabløs, Finn Sverre; Sjursen, Wenche (Peer reviewed; Journal article, 2023)
      Background Hereditary genetic mutations causing predisposition to colorectal cancer are accountable for approximately 30% of all colorectal cancer cases. However, only a small fraction of these are high penetrant mutations ...

    • Detection of Nonadherence to Antihypertensive Treatment by Measurements of Serum Drug Concentrations 

      Bergland, Ola Undrum; Halvorsen, Lene Vernås; Søraas, Camilla Lund; Hjørnholm, Ulla; Kjær, Vibeke Norheim; Rognstad, Stine; Brobak, Karl Marius; Aune, Arleen; Olsen, Eirik; Fauchald, Ylva; Heimark, Sondre; Thorstensen, Christian W; Liestøl, Knut; Solbu, Marit Dahl; Gerdts, Eva; Mo, Rune; Rostrup, Morten; Kjeldsen, Sverre; Høieggen, Aud; Opdal, Mimi Stokke; Fadl Elmula, Fadl Elmula M. (Peer reviewed; Journal article, 2021)
      Nonadherence to drugs is a challenge in hypertension treatment. We aimed to assess the prevalence of nonadherence by serum drug concentrations compared with 2 indirect methods and relate to the prescribed drug regimens in ...

    • Detection of recurrent prostate cancer with 18F-Fluciclovine PET/MRI 

      Selnæs, Kirsten Margrete; Krüger-Stokke, Brage; Elschot, Mattijs; Johansen, Håkon; Steen, Per Arvid; Langørgen, Sverre; Aksnessæther, Bjørg Yksnøy; Indrebø, Gunnar; Sjøbakk, Torill Eidhammer; Tessem, May-Britt; Moestue, Siver Andreas; Knobel, Heidi; Tandstad, Torgrim; Bertilsson, Helena; Solberg, Arne; Bathen, Tone Frost (Peer reviewed; Journal article, 2020)
      Objective: Simultaneous PET/MRI combines soft-tissue contrast of MRI with high molecular sensitivity of PET in one session. The aim of this prospective study was to evaluate detection rates of recurrent prostate cancer by ...

    • Detection of subgenomic mRNA from endemic human coronavirus OC43 and NL63 compared to viral genomic loads, single virus detection and clinical manifestations in children with respiratory tract infections 

      Heimdal, Inger; Lysvand, Hilde; Krokstad, Sidsel; Christensen, Andreas; Døllner, Henrik; Nordbø, Svein Arne (Peer reviewed; Journal article, 2022)
      Background The importance of endemic human coronavirus (HCoV) in children has been insufficiently elucidated upon. Our aims were to develop subgenomic (sg) mRNA tests for HCoV species OC43 and NL63, and to evaluate the ...

    • Determinants for Effective ALECSAT Immunotherapy Treatment on Autologous Patient-Derived Glioblastoma Stem Cells 

      Wenger, Anna; Werlenius, Katja; Hallner, Alexander; Fredrik Bergh, Thoren; Farahmand, Dan; Tisell, Magnus; Smits, Anja; Rydenhag, Bertil; Jakola, Asgeir Store; Caren, Helena (Peer reviewed; Journal article, 2018)
      Glioblastoma (GBM) is the most aggressive primary brain tumor with a median survival of less than 15 months, emphasizing the need for better treatments. Immunotherapy as a treatment for improving or aiding the patient’s ...

    • Determinants of trabecular bone score and prevalent vertebral fractures in women with fragility fractures: a cross-sectional sub-study of NoFRACT 

      Borgen, Tove Tveitan; Bjørnerem, Åshild; Solberg, Lene Bergendal; Andreasen, Camilla; Figved, Wender; Hübschle, Lars Michael; Stenbro, May-Britt; Basso, Trude; Dahl, cecilie; Stutzer, Jens-Meinhard; Frihagen, Frede; Eriksen, Erik Fink; Nordsletten, Lars; Hansen, Ann Kristin; Apalset, Ellen Margrete; Gjertsen, Jan Erik; Lund, Ida (Peer reviewed; Journal article, 2019)
      Summary - Determinants of trabecular bone score (TBS) and vertebral fractures assessed semiquantitatively (SQ1–SQ3) were studied in 496 women with fragility fractures. TBS was associated with age, parental hip fracture, ...

    • Determination of psychoactive drugs in serum using conductive vial electromembrane extraction combined with UHPLC-MS/MS 

      Skaalvik, Tonje Gottenberg; Øiestad, Elisabeth Leere; Trones, Roger; Pedersen-Bjergaard, Stig; Hegstad, Solfrid (Peer reviewed; Journal article, 2021)
      Conductive vial electromembrane extraction (EME) with prototype equipment was applied for the first time to extract lipophilic basic drugs from serum. With this equipment, traditional platinum electrodes were replaced with ...

    • Developing Cognition Endpoints for the CENTER-TBI Neuropsychological Test Battery 

      Stenberg, Jonas; Karr, Justin E.; Terry, Douglas P.; Saksvik, Simen Berg; Vik, Anne; Skandsen, Toril; Silverberg, Noah D.; Iverson, Grant L. (Peer reviewed; Journal article, 2020)
      Background: Measuring cognitive functioning is common in traumatic brain injury (TBI) research, but no universally accepted method for combining several neuropsychological test scores into composite, or summary, scores ...

    • Developing Quality Indicators for Helicopter Emergency Medical Services Coordination in Norwegian Emergency Medical Communication Centrals: A Consensus Process 

      Skjærseth, Eivinn Årdal; Haugland, Helge Nystad; Krüger, Andreas; Næss-Pleym, Lars E.; Uleberg, Oddvar (Peer reviewed; Journal article, 2020)
      Objective Efforts to optimize the use, availability, and safety of helicopter emergency medical services (HEMS) is important. A lack of consistent and comprehensive flight dispatch procedures and a lack of use of safety ...