• Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores 

      de Rojas, Itziar; Moreno-Grau, Sonia; Tesi, Niccolo; Grenier-Boley, Benjamin; Andrade, Victor; Jansen, Iris E.; Rongve, Arvid; Aarsland, Dag; Selbæk, Geir; Saltvedt, Ingvild; Sando, Sigrid Botne; Djurovic, Srdjan; Andreassen, Ole; Pedersen, Nancy L.; Stringa, Najada; Zettergren, Anna; Hernández, Isabel; Montrreal, Laura; Antunez, Carmen; Antonell, Anna; Tankard, Rick; Bis, Joshua C.; Sims, Rebecca; Bellenguez, Celine; Quintela, Inés; González-Pérez, Antonio; Calero, Miguel; Franco-Macias, Emilio; Macias, Juan; Blesa, Rafael; Cervera-Carles, Laura; Menendez-Gonzalez, Manuel; Frank-Garcia, Ana; Royo, José Luis; Moreno, Fermin; Vilas, Raquel Huerto; Baquero, Miquel; Diez-Fairen, Monica; Lage, Carmen; García-Madrona, Sebastian; Garcia-Gonzalez, Pablo; Alarcón-Martín, Emilio; Valero, Sergi; Sotolongo-Grau, Oscar; Ullgren, Abbe; Naj, Adam C.; Lemstra, Afina W.; Benaque, Alba; Perez-Cordon, Alba; Benussi, Alberto; Rabano, Alberto (Peer reviewed; Journal article, 2021)
      Genetic discoveries of Alzheimer’s disease are the drivers of our understanding, and together with polygenetic risk stratification can contribute towards planning of feasible and efficient preventive and curative clinical ...
    • Community paramedicine-cost-benefit analysis and safety with paramedical emergency services in rural areas: scoping review protocol 

      Elden, Odd Erik; Uleberg, Oddvar; Lysne, Marianne; Haugdahl, Hege Selnes (Peer reviewed; Journal article, 2020)
      Introduction Community paramedicine models have been developed around the world in response to demographic changes, healthcare system needs and reforms. The traditional role of the paramedic has primarily been to provide ...
    • Community paramedicine: cost-benefit analysis and safety evaluation in paramedical emergency services in rural areas - a scoping review 

      Elden, Odd Eirik; Uleberg, Oddvar; Lysne, Marianne; Haugdahl, Hege Selnes (Journal article; Peer reviewed, 2022)
    • Community Stakeholders’ Perspectives on Intimate Partner Violence during Pregnancy—A Qualitative Study from Ethiopia 

      Gashaw, Bosena Tebeje; Magnus, Jeanette H.; Schei, Berit; Solbrække, Kari Nyheim (Journal article; Peer reviewed, 2019)
      Abstract:Intimate partner violence (IPV) in pregnancy adversely affects the health of womenand unborn children. To prevent this, the community responses, societal systems, and structuresto support victims of ...
    • Comparability of (Post-Concussion) Symptoms across Time in Individuals after Traumatic Brain Injury: Results from the CENTER-TBI Study 

      Rivera, Diego; Greving, Sven; Arango-Lasprilla, Juan Carlos; von Steinbuechel, Nicole; Zeldovich, Marina; Åkerlund, Cecilia; Vik, Anne; Andelic, Nada; Andreassen, Lasse; Anke, Audny Gabriele Wagner; Skandsen, Toril; Røe, Cecilie; Røise, Olav; Frisvold, Shirin; Antoni, Anna; Audibert, Gérard; Azouvi, Philippe; Azzolini, Maria Luisa; Bartels, Ronald; Benali, Habib; Berardino, Maurizio; Beretta, Luigi; Blaabjerg, Morten; Bragge, Peter; Brazinova, Alexandra; Brinck, Vibeke; Brooker, Joanne; Brorsson, Camilla; Buki, Andras; Bullinger, Monika; Cabeleira, Manuel; Caccioppola, Alessio; Calappi, Emiliana; Calvi, Maria Rosa; Cameron, Peter; Lozano, Guillermo Carbayo; Carbonara, Marco; Cavallo, Simona; Chevallard, Giorgio; Chieregato, Arturo; Citerio, Giuseppe; Clusmann, Hans; Coburn, Mark; Coles, Jonathan; Cooper, Jamie D.; Correia, Marta; Čović, Amra; Curry, Nicola; Czeiter, Endre; Czosnyka, Marek; Dahyot-Fizelier, Claire; Dark, Paul; Dawes, Helen; De Keyser, Veronique; Degos, Vincent; Della Corte, Francesco; den Boogert, Hugo; Depreitere, Bart; Đilvesi, Đula; Dixit, Abhilasha; Donoghue, Emma; Dreier, Jens; Dulière, Guy-Loup; Ercole, Ari; Esser, Patrick; Ezer, Erzsébet; Fabricius, Martin; Feigin, Valery L; Foks, Kelly; Furmanov, Alex; Gagliardo, Pablo; Galanaud, Damien; Gantner, Dashiell; Gao, Guoyi; George, Pradeep; Ghuysen, Alexandre; Giga, Lelde; Glocker, Ben; Golubovic, Jagoš; Gomez, Pedro A.; Gratz, Johannes; Gravesteijn, Benjamin; Grossi, Francesca; Gruen, Russell L (Peer reviewed; Journal article, 2022)
      Post-concussion symptoms often occur after TBI, persist and cause disabilities. The Rivermead Post-Concussion Symptoms Questionnaire (RPQ) is widely used in this population, but little is known about the comparability of ...
    • Comparative analysis of explainable machine learning prediction models for hospital mortality 

      Stenwig, Eline; Salvi, Giampiero; Salvo Rossi, Pierluigi; Skjaervold, Nils Kristian (Peer reviewed; Journal article, 2022)
      Background Machine learning (ML) holds the promise of becoming an essential tool for utilising the increasing amount of clinical data available for analysis and clinical decision support. However, the lack of trust in ...
    • A Comparative Analysis of Orthotopic and Subcutaneous Pancreatic Tumour Models: Tumour Microenvironment and Drug Delivery 

      Lage Fernandez, Jessica; Årbogen, Sara Beate Stjern; Sadeghinia, Mohammadjavad; Haram, Karin Margrete; Snipstad, Sofie; Torp, Sverre Helge; Einen, Caroline; Mühlenpfordt, Melina; Maardalen, Matilde; Vikedal, Krister; Davies, Catharina de Lange (Peer reviewed; Journal article, 2023)
      Pancreatic ductal adenocarcinoma (PDAC) remains a challenging malignancy, mainly due to its resistance to chemotherapy and its complex tumour microenvironment characterised by stromal desmoplasia. There is a need for new ...
    • A comparative biodistribution study of polymeric and lipid-based nanoparticles 

      Åslund, Andreas; Vandebriel, Rob J.; Caputo, Fanny; de Jong, Wim H.; Delmaar, Christiaan; Hyldbakk, Astrid; Rustique, Emilie; Schmid, Ruth Baumberger; Snipstad, Sofie; Texier, Isabelle; Vernstad, Kai; Borgos, Sven Even F. (Peer reviewed; Journal article, 2022)
      Biodistribution of nanoencapsulated bioactive compounds is primarily determined by the size, shape, chemical composition and surface properties of the encapsulating nanoparticle, and, thus, less dependent on the physicochemical ...
    • Comparative effectiveness of decompressive craniectomy versus craniotomy for traumatic acute subdural hematoma (CENTER-TBI): an observational cohort study 

      Van Essen, Thomas; van Erp, Inge A. M.; Lingsma, Hester F; Pisica, Dana; Yue, John K; Singh, Ranjit D.; van Dijck, Jeroen T. J. M.; Volovici, Victor; Younsi, Alexander; Kolias, Angelos; Peppel, Lianne D; Heijenbrok-Kal, Majanka H; Ribbers, Gerard M; Menon, David K; Hutchinson, Peter J A; Manley, Geoffrey T.; Depreitere, Bart; Steyerberg, Ewout W; Maas, Andrew I.R.; de Ruiter, Godard C.W.; Peul, Wilco C.; Åkerlund, Cecilia; Amrein, Krisztina; Andelic, Nada; Andreassen, Lasse; Anke, Audny Gabriele Wagner; Antoni, Anna; Audibert, Gerard; Azouvi, Philippe; Azzolini, Maria Luisa; Bartels, Ronald; Barzó, Pál; Beauvais, Romuald; Beer, Ronny; Bellander, Bo-Michael; Belli, Antonio; Benali, Habib; Berardino, Maurizio; Beretta, Luigi; Blaabjerg, Morten; Bragge, Peter; Brazinova, Alexandra; Brinck, Vibeke; Brooker, Joanne; Brorsson, Camilla; Buki, Andras; Bullinger, Monika; Cabeleira, Manuel; Caccioppola, Alessio; Calappi, Emiliana; Vik, Anne; Røe, Cecilie; Røise, Olav; Skandsen, Toril (Peer reviewed; Journal article, 2023)
      Background Limited evidence existed on the comparative effectiveness of decompressive craniectomy (DC) versus craniotomy for evacuation of traumatic acute subdural hematoma (ASDH) until the recently published randomised ...
    • Comparative effectiveness of intracranial hypertension management guided by ventricular versus intraparenchymal pressure monitoring: a CENTER-TBI study 

      Volovici, Victor; Pisică, Dana; Gravesteijn, Benjamin; Dirven, Clemens M. F.; Steyerberg, Ewout W.; Ercole, Ari; Stocchetti, Nino; Nelson, David; Menon, David K; Citerio, Giuseppe; Van Der Jagt, Mathieu; Maas, Andrew I. R.; Haitsma, Iain K.; Lingsma, Hester F.; Vik, Anne; Skandsen, Toril; Andelic, Nada; Røise, Olav; Helseth, Eirik; Andreassen, Lasse; Anke, Audny Gabriele Wagner; Røe, Cecilie (Peer reviewed; Journal article, 2022)
      Objective To compare outcomes between patients with primary external ventricular device (EVD)–driven treatment of intracranial hypertension and those with primary intraparenchymal monitor (IP)–driven treatment. Methods The ...
    • Comparative retention and effectiveness of migraine preventive treatments: A nationwide registry-based cohort study 

      Bjørk, Marte-Helene; Borkenhagen, Solveig; Oteiza, Francisco; Dueland, Aud N.; Sørgaard, Frank E.; Sæther, Erik Magnus; Bugge, Christoffer (Journal article; Peer reviewed, 2023)
      Background and purpose Little is known about the comparative effects of migraine preventive drugs. We aimed to estimate treatment retention and effectiveness of migraine preventive drugs in a nationwide registry-based ...
    • Comparing manual and automatic scoring of sleep monitoring data from portable polygraphy 

      Kristiansen, Stein; Traaen, Gunn Marit; Øverland, Britt; Plagemann, Thomas Peter; Gullestad, Lars; Akre, Harriet; Nikolaidis, Konstantinos; Aakerøy, Lars; Hunt, Tove Elizabeth Frances; Loennechen, Jan Pål; Steinshamn, Sigurd Loe; Bendz, Christina; Anfinsen, Ole-Gunnar; Goebel, Vera Hermine (Journal article; Peer reviewed, 2020)
      We used sleep monitoring data from a study that investigated the prevalence, characteristics, risk factors and type of sleep apnea (SA) in 579 patients with paroxysmal atrial fibrillation. Most patients were screened for ...
    • Comparing mental distress and help-seeking among first-year medical students in Norway: results of two cross-sectional surveys 20 years apart 

      Ruud, Nora; Løvseth, Lise T; Isaksson Rø, Karin; Tyssen, Reidar (Peer reviewed; Journal article, 2020)
      Objective: To investigate any changes in mental distress levels over 20 years among medical students, as well as the clinical importance of these changes. Design: Two cross-sectional surveys 20 years apart. Setting: The ...
    • Comparison of Care System and Treatment Approaches for Patients with Traumatic Brain Injury in China versus Europe: A CENTER-TBI Survey Study 

      Feng, Junfeng; van Veen, Ernest; Chun, Yang; Huijben, Jilske A.; Lingsma, Hester F; Gao, Guoyi; jiang, jiyao; Maas, Andrew I. R.; Andelic, Nada; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Skandsen, Toril; Vik, Anne (Peer reviewed; Journal article, 2020)
      Traumatic brain injury (TBI) poses a huge public health and societal problem worldwide. Uncertainty exists on how care system and treatment approaches for TBI worked in China may differ from those in Europe. Better knowledge ...
    • Comparison of clinical practice of tonsil surgery from quality register data from Sweden and Norway and one clinic in Denmark 

      Stalfors, Joacim; Ovesen, Therese; Bertelsen, Jannik Buus; Bugten, Vegard; Wennberg, Siri; Sunnergren, Ola (Peer reviewed; Journal article, 2022)
      Objectives To compare the application of indications, demographics, surgical and haemostatic techniques in tonsil surgery in three countries. Design Non-randomised, prospective, observational cohort. Setting All ...
    • Comparison of contrast in brightness mode and strain ultrasonography of glial brain tumours 

      Selbekk, Tormod; Brekken, Reidar; Indergaard, Marit Kristina; Solheim, Ole; Unsgård, Geirmund (Journal article; Peer reviewed, 2012)
      Background Image contrast between normal tissue and brain tumours may sometimes appear to be low in intraoperative ultrasound. Ultrasound imaging of strain is an image modality that has been recently explored for ...
    • Comparison of correctly and incorrectly classified patients for in-hospital mortality prediction in the intensive care unit 

      Stenwig, Eline; Salvi, Giampiero; Salvo Rossi, Pierluigi; Skjaervold, Nils Kristian (Peer reviewed; Journal article, 2023)
      Background The use of machine learning is becoming increasingly popular in many disciplines, but there is still an implementation gap of machine learning models in clinical settings. Lack of trust in models is one of ...
    • A comparison of FDG PET/MR and PET/CT for staging, response assessment, and prognostic imaging biomarkers in lymphoma 

      Husby, Trine; Johansen, Håkon; Bogsrud, Trond; Hustad, Kari Vekseth; Evensen, Birte Veslemøy; Boellard, Ronald; Giskeødegård, Guro F.; Fagerli, Unn-Merete; Eikenes, Live (Peer reviewed; Journal article, 2022)
      The aim of the current study was to investigate the diagnostic performance of FDG PET/MR compared to PET/CT in a patient cohort including Hodgkins lymphoma, diffuse large B-cell lymphoma, and high-grade B-cell lymphoma at ...
    • A comparison of Generative Adversarial Networks for automated prostate cancer detection on T2-weighted MRI 

      Patsanis, Alexandros; Sunoqrot, Mohammed R. S.; Langørgen, Sverre; Wang, Hao; Selnæs, Kirsten Margrete; Bertilsson, Maria Helena; Bathen, Tone Frost; Elschot, Mattijs (Journal article; Peer reviewed, 2023)
      Generative Adversarial Networks (GANs) have shown potential in medical imaging. In this study, several previously developed GANs were investigated for prostate cancer (PCa) detection on T2-weighted (T2W) magnetic resonance ...
    • Comparison of methods to construct a genetic risk score for prediction of rheumatoid arthritis in the population-based Nord-Trøndelag Health Study, Norway 

      Rostami, Sina; Hoff, Mari; Brown, Matthew A.; Hveem, Kristian; Videm, Vibeke (Peer reviewed; Journal article, 2020)
      Objectives: To evaluate selection methods among published single-nucleotide polymorphisms (SNPs) associated with RA to construct predictive genetic risk scores (GRSs) in a population-based setting. Methods: The Nord-Trøndelag ...