• Clinical descriptors of disease trajectories in patients with traumatic brain injury in the intensive care unit (CENTER-TBI): a multicentre observational cohort study 

      Åkerlund, Cecilia A. I.; Holst, Anders; Bhattacharyay, Shubhayu; Stocchetti, Nino; Steyerberg, Ewout; Smielewski, Peter; Menon, David K; Ercole, Ari; Nelson, David W; Amrein, Krisztina; Andelic, Nada; Andreassen, Lasse; Anke, Audny Gabriele Wagner; Antoni, Anna; Audibert, Gérard; Azouvi, Philippe; Skandsen, Toril; Vik, Anne; Frisvold, Shirin; Helseth, Eirik; Azzolini, Maria Luisa; Bartels, Ronald; Barzó, Pál; Beauvais, Romuald; Beer, Ronny; Bellander, Bo-Michael; Belli, Antonio; Benali, Habib; Berardino, Maurizio; Blaabjerg, Morten; Bragge, Peter; Brazinova, Alexandra; Brinck, Vibeke; Brooker, Joanne; Brorsson, Camilla; Buki, Andras; Bullinger, Monika; Cabeleira, Manuel; Caccioppola, Alessio; Calappi, Emiliana; Calvi, Maria Rosa; Cameron, Peter; Carbayo Lozano, Guillermo; Carbonara, Marco; Cavallo, Simona; Chevallard, Giorgio; Chieregato, Arturo; Citerio, Giuseppe; Clusmann, Hans; Coburn, Mark; Coles, Jonathan; Cooper, Jamie D.; Correia, Marta; Čović, Amra; Curry, Nicola; Czeiter, Endre; Czosnyka, Marek; Fizelier, Claire Dahyot; Dark, Paul; Dawes, Helen; De Keyser, Véronique; Degos, Vincent; Della Corte, Francesco; den Boogert, Hugo; Depreitere, Bart; Ðilvesi, Ðula; Dixit, Abhishek; Donoghue, Emma; Dreier, Jens; Dulière, Guy Loup; Esser, Patrick; Ezer, Erzsébet; Fabricius, Martin; Feigin, Valery L.; Foks, Kelly; Furmanov, Alex; Gagliardo, Pablo; Galanaud, Damien; Gantner, Dashiell; Gao, Guoyi; George, Pradeep; Ghuysen, Alexandre; Giga, Lelde; Glocker, Ben; Golubovic, Jagoš; Gomez, Pedro A.; Gratz, Johannes; Gravesteijn, Benjamin; Grossi, Francesca; Gruen, Russell L.; Gupta, Deepak; Haagsma, Juanita A.; Haitsma, Iain; Helbok, Raimund; Horton, Lindsay; Huijben, Jilske; Hutchinson, Peter J.; Jacobs, Bram; Jankowski, Stefan; Jarrett, Mike; Jiang, Jiyao; Johnson, Faye; Jones, Kelly; Karan, Mladen; Kolias, Angelos G.; Kompanje, Erwin; Kondziella, Daniel; Kornaropoulos, Evgenios; Koskinen, Lars Owe; Røe, Cecilie; Røise, Olav (Peer reviewed; Journal article, 2023)
      Background Patients with traumatic brain injury are a heterogeneous population, and the most severely injured individuals are often treated in an intensive care unit (ICU). The primary injury at impact, and the harmful ...
    • Clinical effect modifiers of antibiotic treatment in patients with chronic low back pain and Modic changes - Secondary analyses of a randomised, placebo-controlled trial (the AIM study) 

      Bråten, Lars Christian Haugli; Grøvle, Lars; Espeland, Ansgar; Pripp, Are Hugo; Grotle, Margreth; Hellum, Christian; Haugen, Anne Julsrud; Froholdt, Anne; Rolfsen, Mads Peder; Nygaard, Øystein Petter; Lutro, Olav; Kristoffersen, Per M; Anke, Audny; Schistad, Ellina Iordanova; Skouen, Jan Sture; Brox, Jens Ivar; Zwart, John-Anker; Storheim, Kjersti (Peer reviewed; Journal article, 2020)
      Background Randomised trials on antibiotic treatment for patients with chronic low back pain and vertebral endplate changes visible on MRI (Modic changes) have shown mixed results. A possible explanation might be a real ...
    • Clinical features of suspected Ebola cases referred to the Moyamba ETC, Sierra Leone: Challenges in the later stages of the 2014 outbreak 

      Arranz, Javier; Lundeby, Karen Marie; Hassan, Shoaib; Fuentes, Luis Matías Zabala; Garcés, Pedro San José; Haaskjold, Yngvar Lunde; Bolkan, Håkon Angell; Krogh, Kurt; Jongopi, James; Mellesmo, Sindre; Jøsendal, Ola; Øpstad, Åsmund; Svensen, Erling; Kamara, Alfred Sandy; Roberts, David P.; Stamper, Paul D.; Austin, Paula; Moosa, Alfredo J.; Marke, Dennis; Berg, Åse; Blomberg, Bjørn; Riera, Melcior (Peer reviewed; Journal article, 2016)
      Background - The last ebola virus disease (EVD) outbreak has been the most important since 1976. EVD cases decreased drastically in Sierra Leone at the beginning of 2015. We aim to determine the clinical findings and ...
    • Clinical outcome after knee ligament reconstruction with tendon allografts 

      Drogset, Jon Olav; Størset, Kristina Hovde; Nitteberg, Thea Marie; Gifstad, Tone (Peer reviewed; Journal article, 2021)
      PURPOSE: The purpose of this study is to investigate the clinical outcome for patients after knee ligament reconstructions with allografts at a university hospital. METHODS: A total of 33 patients received allografts for ...
    • Clinical outcomes after surgery for cervical radiculopathy performed in public and private hospitals : a nationwide relative effectiveness study 

      Danielsen, Elisabet; Gulati, Sasha; Salvesen, Øyvind Olav; Ingebrigtsen, Tor; Nygaard, Øystein Petter; Solberg, Tore (Peer reviewed; Journal article, 2023)
      Aims The number of patients undergoing surgery for degenerative cervical radiculopathy has increased. In many countries, public hospitals have limited capacity. This has resulted in long waiting times for elective ...
    • Clinical phenotypes and long-term prognosis in white patients with biopsy-verified hypertensive nephrosclerosis 

      Øvrehus, Marius Altern; Oldereid, Tine Simensen; Dadfar, Aydin; Bjørneklett, Rune; Aasarød, Knut; Fogo, Agnes B.; Ix, Joachim H.; Hallan, Stein (Peer reviewed; Journal article, 2020)
      Introduction Hypertensive nephrosclerosis is considered the second most common cause of end-stage renal disease (ESRD), but it is still an insufficiently studied and controversial disease entity. More information on the ...
    • Clinical Predictors for Analgesic Response to Radiotherapy in Patients with Painful Bone Metastases 

      Habberstad, Ragnhild H; Frøseth, Trude Camilla Salvesen; Aass, Nina Kathrine; Bjerkeset, Gunnhild; Abramova, Tatiana Mikhailovna; Garcia-Alonso, Elena; Caputo, Mariangela; Rossi, Romina; Boland, Jason W.; Brunelli, Cinzia; Lund, Jo-Åsmund; Kaasa, Stein; Klepstad, Pål (Peer reviewed; Journal article, 2021)
      Background Radiotherapy (RT) reduces pain in about 60% of patients with painful bone metastases, leaving many patients without clinical benefit. This study assesses predictors for RT effectiveness in patients with painful ...
    • Clinical trials in pediatric ALS: a TRICALS feasibility study 

      Kliest, Tessa; van Eijk, Ruben P. A.; Al-Chalabi, Ammar; Albanese, Alberto; Andersen, Peter M.; Amador, Maria Del Mar; Bråthen, Geir; Brunaud-Danel, Veronique; Brylev, Lev; Camu, William; de Carvalho, Mamede; Cereda, Cristina; Cetin, Hakan; Chaverri, Delia; Chiò, Adriano; Corcia, Philippe; Couratier, Philippe; De Marchi, Fabiola; Desnuelle, Claude; van Es, Michael A.; Esteban, Jesús; Filosto, Massimiliano; Redondo, Alberto García; Grosskreutz, Julian; Hanemann, Clemens O.; Holmøy, Trygve; Høyer, Helle; Ingre, Caroline; Koritnik, Blaz; Kuzma-Kozakiewicz, Magdalena; Lambert, Thomas; Leigh, Peter N.; Lunetta, Christian; Mandrioli, Jessica; McDermott, Christopher J.; Meyer, Thomas; Mora, Jesus S.; Petri, Susanne; Povedano, Mónica; Reviers, Evy; Riva, Nilo; Roes, Kit C. B.; Rubio, Miguel Á.; Salachas, François; Sarafov, Stayko; Sorarù, Gianni; Stevic, Zorica; Svenstrup, Kirsten; Møller, Anette Torvin; Turner, Martin R.; Van Damme, Philip; van Leeuwen, Lucie A. G.; Varona, Luis; Costa, Juan F. Vázquez; Weber, Markus; Hardiman, Orla; Berg, Leonard H. van den (Peer reviewed; Journal article, 2022)
      Clinical trials in pediatric ALS: a TRICALS feasibility study
    • Clinically accessible neuroimaging predictors of post-stroke neurocognitive disorder: a prospective observational study 

      SCHELLHORN, TILL; Aamodt, Eva Birgitte; Lydersen, Stian; Aam, Stina; Wyller, Torgeir Bruun; Saltvedt, Ingvild; Beyer, Mona Kristiansen (Peer reviewed; Journal article, 2021)
      Background Neurocognitive disorder (NCD) is common in stroke survivors. We aimed to identify clinically accessible imaging markers of stroke and chronic pathology that are associated with early post-stroke NCD. Methods We ...
    • Clinically significant drug-drug interactions involving medications used for symptom control in patients with advanced malignant disease: A systematic review 

      Kotlinska-Lemieszek, Aleksandra; Klepstad, Pål; Haugen, Dagny Faksvåg (Journal article; Peer reviewed, 2019)
      Context Most patients with advanced malignant disease need to take several drugs to control symptoms. This treatment raises risks of serious adverse effects and drug-drug interactions (DDIs). Objectives To identify ...
    • Clonal evolution after treatment pressure in multiple myeloma: heterogenous genomic aberrations and transcriptomic convergence 

      Misund, Kristine; Hofste op Bruinink, Davine; Coward, Eivind; Hoogenboezem, Remco M.; Rustad, Even Holth; Sanders, Mathijs A.; Rye, Morten Beck; Sponaas, Anne-Marit; van der Holt, Bronno; Zweegman, Sonja; Hovig, Eivind; Meza, Leonardo Zepeda; Sundan, Anders; Myklebost, Ola; Sonneveld, Pieter; Waage, Anders (Peer reviewed; Journal article, 2022)
      We investigated genomic and transcriptomic changes in paired tumor samples of 29 in-house multiple myeloma (MM) patients and 28 patients from the MMRF CoMMpass study before and after treatment. A change in clonal composition ...
    • Cluster Headache Genomewide Association Study and Meta-Analysis Identifies Eight Loci and Implicates Smoking as Causal Risk Factor 

      Winsvold, Bendik Kristoffer Slagsvold; Harder, Aster V. E.; Ran, Caroline; Chalmer, Mona A.; Dalmasso, Maria Carolina; Ferkingstad, Egil; Tripathi, Kumar Parijat; Bacchelli, Elena; Børte, Sigrid; Fourier, Carmen; Petersen, Anja S.; Vijfhuizen, Lisanne S.; Magnusson, Sigurdur H.; O'Connor, Emer; Bjornsdottir, Gyda; Häppölä, Paavo; Wang, Yen-Feng; Callesen, Ida; Kelderman, Tim; Gallardo, Victor J; de Boer, Irene; Olofsgård, Felicia Jennysdotter; Heinze, Katja; Lund, Nunu; Thomas, Laurent Francois; Hsu, Chia-Lin; Pirinen, Matti; Hautakangas, Heidi; Ribasés, Marta; Guerzoni, Simona; Sivakumar, Prasanth; Yip, Janice; Heinze, Axel; Küçükali, Fahri; Ostrowski, Sisse R.; Pedersen, Ole B.; Kristoffersen, Espen Saxhaug; Martinsen, Amy; Artigas, María S.; Lagrata, Susie; Cainazzo, Maria Michela; Adebimpe, Joycee; Quinn, Olivia; Göbel, Carl; Cirkel, Anna; Volk, Alexander E.; Heilmann-Heimbach, Stefanie; Skogholt, Anne Heidi; Gabrielsen, Maiken Elvestad; Wilbrink, Leopoldine A.; Danno, Daisuke; Mehta, Dwij; Guðbjartsson, Daníel F.; Rosendaal, Frits Richard; Willems van Dijk, Ko; Fronczek, Rolf; Wagner, Michael; Scherer, Martin; Göbel, Hartmut; Sleegers, Kristel; Sveinsson, Olafur A.; Pani, Luca; Zoli, Michele; Ramos-Quiroga, Josep A.; Dardiotis, Efthimios; Steinberg, Anna; Riedel-Heller, Steffi; Sjöstrand, Christina; Thorgeirsson, Thorgeir E.; Stefansson, Hreinn; Southgate, Laura; Trembath, Richard C.; Vandrovcova, Jana; Noordam, Raymond; Paemeleire, Koen; Stefansson, Kari; Fann, Cathy Shen-Jang; Waldenlind, Elisabet; Tronvik, Erling Andreas; Jensen, Rigmor H.; Chen, Shih-Pin; Houlden, Henry; Terwindt, Gisela M.; Kubisch, Christian; Maestrini, Elena; Vikelis, Michail; Pozo-Rosich, Patricia; Belin, Andrea C.; Matharu, Manjit; van den Maagdenberg, Arn M.J.M.; Hansen, Thomas; Ramirez, Alfredo; Zwart, John Anker Henrik (Peer reviewed; Journal article, 2023)
      Objective The objective of this study was to aggregate data for the first genomewide association study meta-analysis of cluster headache, to identify genetic risk variants, and gain biological insights. Methods A ...
    • Cluster randomised trial to evaluate comprehensive approach to hypertension management in Nepal: a study protocol 

      Bhattarai, Sanju Wagle; Shrestha, Archana; Skovlund, Eva; Åsvold, Bjørn Olav; Mjølstad, Bente Prytz; Sen, Abhijit (Peer reviewed; Journal article, 2023)
      Introduction Despite having effective approaches for hypertension management including use of antihypertensive medication, monitoring of blood pressure and lifestyle modification many people with hypertension in Nepal ...
    • Clustering identifies endotypes of traumatic brain injury in an intensive care cohort: a CENTER-TBI study 

      Åkerlund, Cecilia; Vik, Anne (Peer reviewed; Journal article, 2022)
      Background While the Glasgow coma scale (GCS) is one of the strongest outcome predictors, the current classification of traumatic brain injury (TBI) as ‘mild’, ‘moderate’ or ‘severe’ based on this fails to capture ...
    • The co-occurrence between symptoms of internet gaming disorder and psychiatric disorders in childhood and adolescence: prospective relations or common causes? 

      Hygen, Beate Wold; Skalicka, Vera; Stenseng, Frode; Belsky, Jay; Steinsbekk, Silje; Wichstrøm, Lars (Peer reviewed; Journal article, 2020)
      Internet gaming disorder (IGD) is highlighted as a condition for further study in the Diagnostic and Statistical Manual of Mental Disorders Fifth Edition (DSM‐5). Some studies indicate that IGD appears comorbid with other ...
    • The co-occurrence of motor and language impairments in children evaluated for autism spectrum disorder. An explorative study from Norway. 

      Reindal, Lise; Nærland, Terje; Sund, Anne Mari; Glimsdal, Birgit Avseth; Andreassen, Ole; Weidle, Bernhard (Peer reviewed; Journal article, 2022)
      Background Current research suggest that motor and language impairments are common and closely related in infants with autism spectrum disorder (ASD). In older children, less is known about how these impairments are related ...
    • Code-Free Development and Deployment of Deep Segmentation Models for Digital Pathology 

      Pettersen, Henrik P Sahlin; Belevich, Ilya; Røyset, Elin Synnøve; Smistad, Erik; Simpson, Melanie Rae; Jokitalo, Eija; Reinertsen, Ingerid; Bakke, Ingunn; Pedersen, André (Peer reviewed; Journal article, 2022)
      Application of deep learning on histopathological whole slide images (WSIs) holds promise of improving diagnostic efficiency and reproducibility but is largely dependent on the ability to write computer code or purchase ...
    • Coeliac disease in the Trøndelag Health Study (HUNT), Norway, a population-based cohort of coeliac disease patients 

      Lukina, Polina; Andersen, Ina Lervåg; Eggen, Petter Tinbod; Mjønes, Patricia Gjertrud; Rønne, Elin; Bolstad, Nils; Klaasen, Rolf; Warren, David; Iversen, Rasmus; Hveem, Kristian; Bernklev, Tomm; Jelsness-Jørgensen, Lars-Petter; Pedersen, Lise; Jonkers, Iris; Lagergren, Pernilla; Sollid, Ludvig Magne; Lundin, Knut; Ness-Jensen, Eivind (Peer reviewed; Journal article, 2024)
      Purpose - Coeliac disease (CD) is a common disorder and affects about 1% of the population worldwide. CD in the Trøndelag Health Study (HUNT) is a population-based cohort study which was established to provide new knowledge ...
    • Cognitive and Emotional Impairment after Minor Stroke and Non-ST-Elevation Myocardial Infarction (NSTEMI): A Prevalence Study 

      Morsund, Åse Hagen; Ellekjær, Hanne; Gramstad, Arne; Reiestad, Magnus Tallaksen; Midgard, Rune; Sando, Sigrid Botne; Jonsbu, Egil; Næss, Halvor (Journal article; Peer reviewed, 2019)
      Aim. To study the prevalence of cognitive and emotional impairment following a minor ischemic stroke compared to an age-matched group with non-ST-elevation myocardial infarction (NSTEMI). Methods. We included patients aged ...
    • Cognitive behavior therapy for adult eating disorders in routine clinical care: A systematic review and meta-analysis 

      Öst, Lars Gøran; Brattmyr, Lars Martin; Finnes, Anna; Ghaderi, Ata; Havnen, Audun; Hedman-Lagerlöf, Maria; Parling, Thomas; Welch, Elisabeth; Wergeland, Gro Janne Henningsen (Peer reviewed; Journal article, 2023)