• Functional Brain Hyperactivations Are Linked to an Electrophysiological Measure of Slow Interhemispheric Transfer Time after Pediatric Moderate/Severe Traumatic Brain Injury 

      Olsen, Alexander; Babikian, Talin; Dennis, Emily L.; Ellis-Blied, Monica U.; Giza, Christopher C.; Marion, Sarah DeBoard; Mink, Richard; Johnson, Jeffrey; Babbitt, Christopher; Thompson, Paul M.; Asarnow, Robert F. (Peer reviewed; Journal article, 2020)
      Increased task-related blood oxygen level dependent (BOLD) activation is commonly observed in functional magnetic resonance imaging (fMRI) studies of moderate/severe traumatic brain injury (msTBI), but the functional ...
    • Functional outcome and survival following spontaneous intracerebral hemorrhage: A retrospective population-based study 

      Øie, Lise Rystad; Madsbu, Mattis Aleksander; Solheim, Ole; Jakola, Asgeir Store; Giannadakis, Charalampis; Vorhaug, Anders; Padayachy, Llewellyn; Jensberg, Heidi; Dodick, David W.; Salvesen, Øyvind; Gulati, Sasha (Journal article; Peer reviewed, 2018)
      Background Accurate and reliable clinical and radiological predictors of intracerebral hemorrhage (ICH) outcomes are needed to optimize treatment of ICH. The aim of this study was to investigate functional outcome and ...
    • Functional properties of habenular neurons are determined by developmental stage and sequential neurogenesis 

      Fore, Stephanie Liesbeth; Acuna Hinrichsen, Francisca Daniela; Mutlu, Aytac Kadir; Bartoszek-Kandler, Ewelina Magdalena; Serneels, Bram; Faturos, Nicholas Guy; Chau, Khac Thanh Phong; Cosacak, Mehmet Ilyas; Diaz Verdugo, Carmen; Palumbo, Fabrizio; Ringers, Christa; Jurisch-Yaksi, Nathalie; Kizil, Caghan; Yaksi, Emre (Peer reviewed; Journal article, 2020)
      The developing brain undergoes drastic alterations. Here, we investigated developmental changes in the habenula, a brain region that mediates behavioral flexibility during learning, social interactions, and aversive ...
    • Fysioterapi ved kneartrose: En observasjonell studie av epikriser 

      Grønhaug, Gudmund; Grønhaug, Kirsten Marie; Stensdotter, Ann-Katrin (Journal article; Peer reviewed, 2014)
      Bakgrunn: Kneartrose er en av de hyppigst forekommende formene for artrose og er en av de enkeltdiagnosene som forårsaker høyest grad av selvopplevd reduksjon av livskvalitet og nedsatt arbeidsevne. Ubehandlet kneartrose ...
    • Game on: a cycling exergame can elicit moderate-to-vigorous intensity. A pilot study 

      Berg, Jonathan; Moholdt, Trine (Peer reviewed; Journal article, 2020)
      Objectives The aims of this pilot study were to investigate oxygen uptake (V̇O2) while playing a cycling exergame to assess exercise intensity to determine its potential as a feasible exercise alternative to improve aerobic ...
    • Gastric Carcinomas Localized to the Cardia 

      Bakkelund, Karin Elvenes; Nordrum, Ivar Skjåk; Fossmark, Reidar; Waldum, Helge (Journal article; Peer reviewed, 2012)
      Objectives. Gastric adenocarcinomas localized to the cardia are increasing. Enterochromaffin-like (ECL) cells play a role in gastric carcinogenesis in hypergastrinemia, and the use of proton pump inhibitors (PPI) leading ...
    • Gender, class, employment status and social mobility following spinal cord injury in Denmark, the Netherlands, Norway and Switzerland 

      Leiulfsrud, Annelie; Solheim, Erling; Reinhardt, Jan D; Post, Marcel W. M.; Horsewell, Jane; Biering-Sørensen, Fin; Leiulfsrud, Håkon (Peer reviewed; Journal article, 2019)
      Study design: Cross sectional survey of 1055 persons with spinal cord injury (SCI) in Denmark, the Netherlands, Norway and Switzerland. Objectives: (1) To analyse the employment levels of people of working age with SCI, ...
    • Gene expression studies and targeted metabolomics reveal disturbed serine, methionine, and tyrosine metabolism in early hypertensive nephrosclerosis 

      Øvrehus, Marius Altern; Bruheim, Per; Ju, Wenjun; Zelnick, Leila R.; Langlo, Knut Asbjørn Rise; Sharma, Kumar; de Boer, Ian H.; Hallan, Stein (Journal article; Peer reviewed, 2019)
      Introduction Hypertensive nephrosclerosis is among the leading causes of end-stage renal disease, but its pathophysiology is poorly understood. We wanted to explore early metabolic changes using gene expression and targeted ...
    • Gene signatures ESC, MYC and ERG-fusion are early markers of a potentially dangerous subtype of prostate cancer 

      Rye, Morten Beck; Bertilsson, Helena; Drabløs, Finn; Angelsen, Anders; Bathen, Tone Frost; Tessem, May-Britt (Journal article; Peer reviewed, 2014)
      Background Good prognostic tools for predicting disease progression in early stage prostate cancer (PCa) are still missing. Detection of molecular subtypes, for instance by using microarray gene technology, can give new ...
    • General and alcohol-related social media use and mental health: A large-sample longitudinal study 

      Erevik, Eilin K.; Pallesen, Ståle; Vedaa, Øystein; Andreassen, Cecilie Schou; Dhir, Amandeep; Torsheim, Torbjørn (Peer reviewed; Journal article, 2020)
      The current study aimed to investigate if general and alcohol-related social media use predicts symptoms of depression and anxiety. Students in Bergen, Norway, participated in a Web-based survey during fall 2015 (T1) and ...
    • General Health, Vitality, and Social Function After Sinus Surgery in Chronic Rhinosinusitis 

      Nilsen, Ann Helen; Helvik, Anne-Sofie; Thorstensen, Wenche Moe; Salvesen, Øyvind; Bugten, Vegard (Journal article; Peer reviewed, 2019)
      Objectives Chronic rhinosinusitis (CRS) has an impact on health‐related quality of life (HRQOL). The objective of this study was to examine generic and disease‐specific HRQOL and symptoms in CRS patients with (CRSwNP) ...
    • Generation of a Mouse Model Lacking the Non-Homologous End-Joining Factor Mri/Cyren 

      Castaneda Zegarra, Sergio Miguel; Huse, Camilla; Røsand, Øystein; Sarno, Antonio; Xing, Mengtan; Zhang, Qindong; Alirezaylavasani, Amin; Werner, Julia; Ji, Ping; Liabakk, Nina-Beate; Wang, Wei; Bjørås, Magnar; Oksenych, Valentyn (Journal article; Peer reviewed, 2019)
      Classical non-homologous end joining (NHEJ) is a molecular pathway that detects, processes, and ligates DNA double-strand breaks (DSBs) throughout the cell cycle. Mutations in several NHEJ genes result in neurological ...
    • Genetic architecture of subcortical brain structures in 38,851 individuals 

      Satizabal, Claudia L.; Adams, Hieab H.H.; Hibar, Derrek; White, Charles C.; Knol, Maria J.; Stein, Jason L.; Scholz, Markus; Sargurupremraj, Muralidharan; Jahanshad, Neda; Roshchupkin, Gennady V.; Smith, Albert V.; Bis, Joshua C.; Jian, Xueqiu; Luciano, Michelle; Hofer, Edith; Teumer, Alexander; van der Lee, Sven J.; Yang, Jingyun; Yanek, Lisa R.; Lee, Tom V.; Li, Shuo; Hu, Yanhui; Koh, Jia Yu; Eicher, John D.; Desrivières, Sylvane; Arias-Vasquez, Alejandro; Chauhan, Ganesh; Athanasiu, Lavinia; Rentería, Miguel E.; Kim, Sungeun; Hoehn, David; Armstrong, Nicola J.; Chen, Qiang; Holmes, Avram J.; den Braber, Anouk; Kloszewska, Iwona; Andersson, Micael; Espeseth, Thomas; Grimm, Oliver; Abramovic, Lucija; Alhusaini, Saud; Milaneschi, Yuri; Papmeyer, Martina; Axelsson, Tomas; Ehrlich, Stefan; Roiz-Santiáñez, Roberto; Kraemer, Bernd; Håberg, Asta; Jones, Hannah J; Pike, G. Bruce; Stein, Dan J.; Stevens, Allison; Bralten, Janita; Vernooij, Meike W.; Harris, Tamara B.; Filippi, Irina; Witte, A Veronica; Guadalupe, Tulio; Wittfeld, Katharina; Mosley, Thomas H.; Becker, James T.; Doan, Nhat Trung; Hagenaars, Saskia P.; Saba, Yasaman; Cuellar-Partida, Gabriel; Amin, Najaf; Hilal, Saima; Nho, Kwangsik; Mirza-Schreiber, Nazanin; Arfanakis, Konstantinos; Becker, Diane M.; Ames, David; Goldman, Aaron L.; Lee, Phil H.; Boomsma, Dorret I.; Lovestone, Simon; Giddaluru, Sudheer; Le Hellard, Stephanie; Mattheisen, Manuel; Bohlken, Marc M.; Kasperaviciute, Dalia; Schmaal, Lianne; Lawrie, Stephen M.; Agartz, Ingrid; Walton, Esther; Tordesillas-Gutierrez, Diana; Davies, Gareth E.; Shin, Jean; Ipser, Jonathan C.; Vinke, Louis N.; Hoogman, Martine; Jia, Tianye; Burkhardt, Ralph; Klein, Marieke; Crivello, Fabrice; Janowitz, Deborah; Carmichael, Owen; Haukvik, Unn Kristin H.; Aribisala, Benjamin S.; Schmidt, Helena; Strike, Lachlan T.; Cheng, Ching-Yu; Risacher, Shannon L.; Putz, Benno; Fleischman, Debra A.; Assareh, Amelia A.; Mattay, Venkata S.; Buckner, Randy L.; Mecocci, Patrizia; Dale, Anders; Cichon, Sven; Boks, Marco P.; Matarin, Mar; Penninx, Brenda W.J.H.; Calhoun, Vince D.; Chakravarty, M. Mallar; Marquand, André F.; Macare, Christine; Kharabian Masouleh, Shahrzad; Oosterlaan, Jaap; Amouyel, Philippe; Hegenscheid, Katrin; Rotter, Jerome I.; Schork, Andrew J.; Liewald, David C.M.; de Zubicaray, Greig I.; Wong, Tien Yin; Shen, Li; Sämann, Philipp G.; Brodaty, Henry; Roffman, Joshua L.; de Geus, Eco J.C.; Tsolaki, Magda; Erk, Susanne; van Eijk, Kristel R.; Cavalleri, Gianpiero L.; Van Der Wee, Nic J.A.; McIntosh, Andrew M.; Gollub, Randy L.; Bulayeva, Kazima B.; Bernard, Manon; Richards, Jennifer S.; Himali, Jayandra J.; Loeffler, Markus; Rommelse, Nanda; Hoffmann, Wolfgang; Westlye, Lars Tjelta; Valdés Hernández, Maria C.; Hansell, Narelle K.; van Erp, Theo G.M.; Wolf, Christiane; Kwok, John B.J.; Vellas, Bruno; Heinz, Andreas; Olde Loohuis, Loes M.; Delanty, Norman; Ho, Beng-Choon; Ching, Christopher R.K.; Shumskaya, Elena; Singh, Baljeet; Hofman, Albert; van der Meer, Dennis; Homuth, Georg; Psaty, Bruce M.; Bastin, Mark E.; Montgomery, Grant W.; Foroud, Tatiana M.; Reppermund, Simone; Hottenga, Jouke-Jan; Simmons, Andrew; Meyer-Lindenberg, Andreas; Cahn, Wiepke; Whelan, Christopher D; van Donkelaar, Marjolein M.J.; Yang, Qiong; Hosten, Norbert; Green, Robert C.; Thalamuthu, Anbupalam; Mohnke, Sebastian; Hulshoff Pol, Hilleke E.; Lin, Honghuang; Jack, Clifford R.; Schofield, Peter R.; Mühleisen, Thomas W.; Maillard, Pauline; Potkin, Steven G.; Wen, Wei; Fletcher, Evan; Toga, Arthur W.; Gruber, Oliver; Huentelman, Matthew; Davey Smith, George; Launer, Lenore J.; Nyberg, Lars; Jönsson, Erik Gunnar; Crespo-Facorro, Benedicto; Koen, Nastassja; Greve, Douglas N.; Uitterlinden, André G.; Weinberger, Daniel R.; Steen, Vidar Martin; Fedko, Iryna O.; Groenewold, Nynke A.; Niessen, Wiro J.; Toro, Roberto; Tzourio, Christophe; Longstreth, William T.; Ikram, M. Kamran; Smoller, Jordan W.; van Tol, Marie-Jose; Sussmann, Jessika E.; Paus, Tomáš; Lemaître, Hervé; Schroeter, Matthias L.; Mazoyer, Bernard; Andreassen, Ole Andreas; Holsboer, Florian; Depondt, Chantal; Veltman, Dick J.; Turner, Jessica A.; Pausova, Zdenka; Schumann, Gunter; van Rooij, Daan; Djurovic, Srdjan; Deary, Ian J.; McMahon, Katie L; Müller-Myhsok, Bertram; Brouwer, Rachel M.; Soininen, Hilkka; Pandolfo, Massimo; Wassink, Thomas H.; Cheung, Joshua W.; Wolfers, Thomas; Martinot, Jean-Luc; Zwiers, Marcel P.; Nauck, Matthias; Melle, Ingrid; Martin, Nicholas G.; Kanai, Ryota; Westman, Eric; Kahn, René S.; Sisodiya, Sanjay M.; White, Tonya; Saremi, Arvin; van Bokhoven, Hans; Brunner, Han G.; Völzke, Henry; Wright, Margaret J.; van `t Ent, Dennis; Nöthen, Markus M.; Ophoff, Roel A.; Buitelaar, Jan K.; Fernandéz, Guillén; Sachdev, Perminder S.; Rietschel, Marcella; van Haren, Neeltje E.M.; Fisher, Simon E.; Beiser, Alexa S.; Francks, Clyde; Saykin, Andrew J.; Mather, Karen A.; Romanczuk-Seiferth, Nina; Hartman, Catharina A.; DeStefano, Anita L; Heslenfeld, Dirk J.; Weiner, Michael W.; Walter, Henrik; Hoekstra, Pieter J.; Nyquist, Paul A.; Franke, Barbara; Bennett, David A.; Grabe, Hans J.; Johnson, Andrew D.; Chen, Christopher; van Duijn, Cornelia M.; Lopez, Oscar L.; Fornage, Myriam; Wardlaw, Joanna M.; Schmidt, Reinhold; DeCarli, Charles; De Jager, Philip L.; Villringer, Arno; Debette, Stéphanie; Gudnason, Vilmundur; Medland, Sarah E.; Shulman, Joshua M.; Thompson, Paul M.; Seshadri, Sudha; Ikram, M. Arfan (Journal article, 2019)
      Subcortical brain structures are integral to motion, consciousness, emotions and learning. We identified common genetic variation related to the volumes of the nucleus accumbens, amygdala, brainstem, caudate nucleus, globus ...
    • Genetic associations with temporal shifts in obesity and severe obesity during the obesity epidemic in Norway: A longitudinal population-based cohort (the HUNT Study) 

      Brandkvist, Maria Charlotta; Bjørngaard, Johan Håkon; Ødegård, Rønnaug; Brumpton, Ben Michael; Smith, George Davey; Åsvold, Bjørn Olav; Sund, Erik; Kvaløy, Kirsti; Willer, Cristen J.; Vie, Gunnhild Åberge (Peer reviewed; Journal article, 2020)
      Background Obesity has tripled worldwide since 1975 as environments are becoming more obesogenic. Our study investigates how changes in population weight and obesity over time are associated with genetic predisposition ...
    • Genetic control of variability in subcortical and intracranial volumes 

      Còrdova Palomera, Aldo; van der Meer, Dennis; Kaufmann, Tobias; Bettella, Francesco; Wang, Yunpeng; Alnæs, Dag; Doan, Nhat Trung; Agartz, Ingrid; Bertolino, Alessandro; Buitelaar, Jan; Coynel, David; Djurovic, Srdjan; Dørum, Erlend Solberg; Espeseth, Thomas; Fazio, Leonardo; Franke, Barbara; Frei, Oleksandr; Håberg, Asta; Le Hellard, Stephanie; Jönsson, Erik Gunnar; Kolskår, Knut-Kristian; Lund, Martina Jonette; Moberget, Torgeir; Nordvik, Jan; Nyberg, Lars; Papassotiropoulos, Andreas; Pergola, Giulio; de Quervain, Dominique; Rampino, Antonio; Richard, Geneviève; Rokicki, Jaroslav; Sanders, Anne-Marthe; Schwarz, Emanuel; Smeland, Olav Bjerkehagen; Steen, Vidar Martin; Starrfelt, Jostein; Sønderby, Ida Elken; Ulrichsen, Kristine Moe; Andreassen, Ole Andreas; Westlye, Lars Tjelta (Peer reviewed; Journal article, 2020)
      Sensitivity to external demands is essential for adaptation to dynamic environments, but comes at the cost of increased risk of adverse outcomes when facing poor environmental conditions. Here, we apply a novel methodology ...
    • Genetic interaction between the non‐homologous end joining factors during B and T lymphocyte development: in vivo mouse models 

      Castaneda Zegarra, Sergio Miguel; Fernandez Berrocal, Marion Silvana; Tkachev, Max; Yao, Rouan; Esnardo Upfold, Nikki Lyn; Oksenych, Valentyn (Peer reviewed; Journal article, 2020)
      Non-homologous end joining (NHEJ) is the main DNA repair mechanism for the repair of double-strand breaks (DSBs) throughout the course of the cell cycle. DSBs are generated in developing B and T lymphocytes during V(D)J ...
    • Genetic polymorphisms associated with sleep-related phenotypes; relationships with individual nocturnal symptoms of insomnia in the HUNT study 

      Bragantini, Daniela; Sivertsen, Børge; Gehrman, Philip; Lydersen, Stian; Guzey, Ismail Cuneyt (Journal article; Peer reviewed, 2019)
      Background In recent years, several GWAS (genome wide association studies) of sleep-related traits have identified a number of SNPs (single nucleotides polymorphism) but their relationships with symptoms of insomnia are ...
    • Genetic risk score associations for myocardial infarction are comparable in persons with and without rheumatoid arthritis: the population-based HUNT study 

      Rostami, Sina; Hoff, Mari; Dalen, Håvard; Hveem, Kristian; Videm, Vibeke (Peer reviewed; Journal article, 2020)
      Persons with rheumatoid arthritis (RA) have increased risk of myocardial infarction (MI). Overlapping associations with MI of weighted genetic risk scores (wGRS) for coronary artery disease (CAD) and RA is unknown in a ...
    • Genetic variation and cognitive dysfunction in opioid-treated patients with cancer 

      Kurita, Geana Paula; Ekholm, Ola; Kaasa, Stein; Klepstad, Pål; Skorpen, Frank; Sjøgren, Per (Peer reviewed; Journal article, 2016)
      Background and purpose The effects of single‐nucleotide polymorphisms (SNPs) on the cognitive function of opioid‐treated patients with cancer until now have not been explored, but they could potentially be related to ...
    • Genetically-controlled Vesicle-Associated Membrane Protein 1 expression may contribute to Alzheimer's pathophysiology and susceptibility 

      Sevlever, Daniel; Zou, Fang Geng; Ma, Li; Carrasquillo, Sebastian; Crump, Michael G; Culley, Oliver J; Hunter, Talisha A; Bisceglio, Gina; Younkin, Linda; Allen, Mariet; Carrasquillo, Minerva; Sando, Sigrid Botne; Aasly, Jan; Dickson, Dennis W; Graff-Radford, Neill; Petersen, Ronald C.; Morgan, Kevin; Belbin, Olivia (Journal article; Peer reviewed, 2015)
      Background Alzheimer’s disease is a neurodegenerative disorder in which extracellular deposition of β-amyloid (Aβ) oligomers causes synaptic injury resulting in early memory loss, altered homeostasis, accumulation of ...