• Animal models to study the role of long-term hypergastrinemia in gastric carcinogenesis 

      Fossmark, Reidar; Qvigstad, Gunnar; Martinsen, Tom Christian; Hauso, Øyvind; Waldum, Helge (Journal article; Peer reviewed, 2011)
      Patients with chronic hypergastrinemia due to chronic atrophic gastritis or gastrinomas have an increased risk of developing gastric malignancy, and it has been questioned whether also patients with hypergastrinemia caused ...
    • The central role of gastrin in gastric cancer 

      Waldum, Helge; Mjønes, Patricia Gjertrud (Peer reviewed; Journal article, 2023)
      The prevalence of gastric cancer has markedly declined, but due to the high mortality rates associated with gastric cancer, it is still a serious disease. The preferred classification of gastric cancer is according to ...
    • Chronic diseases: what about infections of virus and prions via the gut? 

      Waldum, Helge; Martinsen, Tom Christian (Peer reviewed; Journal article, 2021)
    • Gastritis, Gastric Polyps and Gastric Cancer 

      Waldum, Helge; Fossmark, Reidar (Peer reviewed; Journal article, 2021)
      Gastric cancer is still an important disease causing many deaths worldwide, although there has been a marked reduction in prevalence during the last few decades. The decline in gastric cancer prevalence is due to a reduction ...
    • Role of Autoimmune Gastritis in Gastric Cancer 

      Waldum, Helge; Fossmark, Reidar (Journal article; Peer reviewed, 2019)
      It has been known for 70 years that gastric cancer occurs mainly in a stomach with gastritis. Gastritis was previously so prevalent that it was regarded as an aging phenomenon. Since the description of Helicobacter pylori ...
    • Serotonin—A Driver of Progressive Heart Valve Disease 

      Waldum, Helge; Wahba, Alexander (Peer reviewed; Journal article, 2022)
      It is well known that some serotoninergic drugs and neuroendocrine tumors producing serotonin (5-HT) may induce valvular heart disease by stimulation of proliferation of valvular cells via interaction with a 5-HT receptor ...
    • Time to classify tumours of the stomach and the kidneys according to cell of origin 

      Waldum, Helge; Mjønes, Patricia (Peer reviewed; Journal article, 2021)
      Abstract: Malignant tumours are traditionally classified according to their organ of origin and whether they are of epithelial (carcinomas) or mesenchymal (sarcomas) origin. By histological appearance the site of origin ...