• Associations between Measured and Patient-Reported Physical Function and Survival in Advanced NSCLC 

      Stokke, Kristin; Halvorsen, Tarje Onsøien; Grønberg, Bjørn Henning; Saltvedt, Ingvild; Jordhøy, Marit Slaaen; Kirkevold, Øyvind; Killingberg, Kristin Toftaker; Sandvei, Marie Søfteland (Peer reviewed; Journal article, 2022)
      Background: There is a lack of tools for selecting patients with advanced lung cancer who benefit the most from systemic treatment. Patient-reported physical function (PRPF) has been identified as a prognostic factor in ...
    • Associations between post-stroke motor and cognitive function: a cross-sectional study 

      Einstad, Marte Stine; Saltvedt, Ingvild; Lydersen, Stian; Ursin, Marie Helene; Munthe-Kaas, Ragnhild; Ihle-Hansen, Hege; Askim, Torunn; Beyer, Mona K.; Næss, Halvor; Seljeseth, Yngve Müller; Ellekjær, Hanne; Thingstad, Pernille (Peer reviewed; Journal article, 2021)
      Background Motor and cognitive impairments are frequently observed following stroke, but are often managed as distinct entities, and there is little evidence regarding how they are related. The aim of this study was to ...
    • Cerebrospinal fluid sTREM2 in Alzheimer’s disease: comparisons between clinical presentation and AT classification 

      Knapskog, Anne Brita; Henjum, Kristi; Idland, Ane-Victoria; Eldholm, Rannveig Sakshaug; Persson, Karin Ester Torun; Saltvedt, Ingvild; Watne, Leiv; Engedal, Knut; Nilsson, Lars N.G. (Peer reviewed; Journal article, 2020)
      Triggering receptor expressed on myeloid cells 2 (TREM2) is an innate immune receptor expressed by microglia. Its cleaved fragments, soluble TREM2 (sTREM2), can be measured in the cerebrospinal fluid (CSF). Previous studies ...
    • Client, caregiver, volunteer, and therapist views on a voluntary supported group exercise programme for older adults with dementia 

      Taraldsen, Kristin; Boulton, Elisabeth; Helbostad, Jorunn L.; Saltvedt, Ingvild; Granbo, Randi (Peer reviewed; Journal article, 2020)
      Background: Existing group exercise programmes, or other services offered to maintain physical activity levels, are typically not developed specifically for older adults with dementia. The aim of this study was to gain ...
    • Delirium og kognitiv svikt blant eldre i norske akuttmottak 

      Evensen, Sigurd; Saltvedt, Ingvild; Ranhoff, Anette Hylen; Myrstad, Marius; Myrstad, Christian; Mellingsæter, Marte; Wang-Hansen, Marte Sofie; Neerland, Bjørn Erik (Journal article; Peer reviewed, 2019)
      BAKGRUNN Delirium er vanlig og underdiagnostisert blant pasienter på sykehus og er assosiert med komplikasjoner, økt dødelighet, demensutvikling og behov for sykehjemsplass. Kognitiv svikt av andre årsaker er også vanlig ...
    • The delirium screening tool 4AT in routine clinical practice: prediction of mortality, sensitivity and specificity 

      Evensen, Sigurd; Hylen Ranhoff, Anette; Lydersen, Stian; Saltvedt, Ingvild (Peer reviewed; Journal article, 2021)
      Purpose Delirium is common and associated with poor outcomes, partly due to underdetection. We investigated if the delirium screening tool 4 A’s test (4AT) score predicts 1 year mortality and explored the sensitivity and ...
    • Development and delivery of patient treatment in the Trondheim Hip Fracture Trial. A new geriatric in-hospital pathway for elderly patients with hip fracture 

      Saltvedt, Ingvild; Prestmo, Anders; Einarsen, Elin Kristin; Johnsen, Lars Gunnar; Helbostad, Jorunn L.; Sletvold, Olav (Journal article; Peer reviewed, 2012)
      Background Hip fractures are common among frail elderly persons and often have serious consequences on function, mobility and mortality. Traditional treatment of these patients is performed in orthopedic departments without ...
    • Effect of in-hospital comprehensive geriatric assessment (CGA) in older people with hip fracture. The protocol of the Trondheim Hip Fracture Trial 

      Sletvold, Olav; Helbostad, Jorunn L.; Thingstad, Pernille; Taraldsen, Kristin; Prestmo, Anders; Lamb, SE; Aamodt, Arild; Johnsen, Roar; Magnussen, Jon; Saltvedt, Ingvild (Journal article; Peer reviewed, 2011)
      Background Hip fractures in older people are associated with high morbidity, mortality, disability and reduction in quality of life. Traditionally people with hip fracture are cared for in orthopaedic departments without ...
    • Genome-wide association identifies the first risk loci for psychosis in Alzheimer disease 

      DeMichele-Sweet, Mary Ann A.; Klei, Lambertus; Creese, Byron; Harwood, Janet C.; Weamer, Elise A.; McClain, Lora; Sims, Rebekka; Hernández, Isabel; Moreno-Grau, Sonia; Tárraga, Lluís; Boada, Mercè; Alarcón-Martín, Emilio; Valero, Sergi; Liu, Yushi; Hooli, Basavaraj; Aarsland, Dag; Selbæk, Geir; Bergh, Sverre; Rongve, Arvid; Saltvedt, Ingvild; Skjellegrind, Håvard; Engdahl, Bo Lars; Stordal, Eystein; Andreassen, Ole Andreas; Djurovic, Srdjan; Athanasiu, Lavinia; Seripa, Davide; Borroni, Barbara; Albani, Diego; Forloni, Gianluigi; Mecocci, Patrizia; Seretti, Alessandro; De Ronchi, Diana; Politis, Antonis; Williams, Julie; Mayeux, Richard; Foroud, Tatiana; Ruiz, Agustin; Ballard, Clive; Holmans, Peter; Lopez, Oscar L.; Kamboh, M. Ilyas; Devlin, Bernie; Sweet, Robert A. (Peer reviewed; Journal article, 2021)
      Psychotic symptoms, defined as the occurrence of delusions or hallucinations, are frequent in Alzheimer disease (AD with psychosis, AD + P). AD + P affects ~50% of individuals with AD, identifies a subgroup with poor ...
    • Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk 

      Jansen, Iris E.; Savage, Jeanne E.; Watanabe, Kyoko; Bryois, Julien; Williams, Dylan M.; Steinberg, Stacy; Sealock, Julia; Karlsson, Ida K.; Hägg, Sara; Athanasiu, Lavinia; Voyle, Nicola; Proitsi, Petroula; Witoelar, Aree; Stringer, Sven; Aarsland, Dag; Almdahl, Ina Selseth; Andersen, Fred; Bergh, Sverre; Bettella, Francesco; Björnsson, Sigurbjörn; Brækhus, Anne; Bråthen, Geir; de Leeuw, Christiaan A.; Desikan, Rahul S.; Djurovic, Srdjan; Dumitrescu, Logan; Fladby, Tormod; Hohman, Timothy J.; Jónsson, Pálmi V.; Kiddle, Steven J; Rongve, Arvid; Saltvedt, Ingvild; Sando, Sigrid Botne; Selbæk, Geir; Shoai, Maryam; Skene, Nathan G.; Snædal, Jón G.; Stordal, Eystein; Ulstein, Ingun; Wang, Yunpeng; White, Linda Rosemary; Hardy, John; Hjerling-Leffler, Jens; Sullivan, Patrick; van der Flier, Wiesje M.; Dobson, Richard; Davis, Lea K; Stefánsson, Hreinn; Stefánsson, Kári; Pedersen, Nancy L; Ripke, Stephan; Andreassen, Ole Andreas; Posthuma, Danielle (Journal article; Peer reviewed, 2019)
      Alzheimer’s disease (AD) is highly heritable and recent studies have identified over 20 disease-associated genomic loci. Yet these only explain a small proportion of the genetic variance, indicating that undiscovered loci ...
    • Interdisciplinary care of hip fractures: Orthogeriatric models, alternative models, interdisciplinary teamwork 

      Ranhoff, Anette Hylen; Saltvedt, Ingvild; Frihagen, Frede Jon; Ræder, Johan; Maini, Sameer; Sletvold, Olav (Journal article; Peer reviewed, 2019)
      Hip fractures are common among older people, and the prognosis is serious in terms of mobility, independence in daily life activities, and cognition, with 42% of patients never achieving the same function as before the ...
    • Investigating novel biomarkers of immune activation and modulation in the context of sedentary behaviour: a multicentre prospective ischemic stroke cohort study 

      Alme, Katinka Nordheim; Askim, Torunn; Assmus, Jörg; Mollnes, Tom Eirik; Naik, Mala; Næss, Halvor; Saltvedt, Ingvild; Ueland, Per-Magne; Ulvik, Arve; Knapskog, Anne-Brita (Peer reviewed; Journal article, 2021)
      Background Sedentary behaviour is associated with disease, but the molecular mechanisms are not understood. Valid biomarkers with predictive and explanatory properties are required. Therefore, we have investigated traditional ...
    • Is long-bout sedentary behaviour associated with long-Term glucose levels 3 months after acute ischaemic stroke? A prospective observational cohort study 

      Alme, Katinka Nordheim; Knapskog, Anne Brita; Næss, Halvor; Naik, Mala; Beyer, Mona K.; Ellekjær, Hanne; English, Coralie; Ihle-Hansen, Hege; Kummeneje, Camilla S.; Munthe-Kaas, Ragnhild; Saltvedt, Ingvild; Seljeseth, Yngve Müller; Tan, Xiang chun; Thingstad, Pernille; Askim, Torunn (Peer reviewed; Journal article, 2020)
      Background and purpose Sedentary behaviour is a risk factor for vascular disease and stroke patients are more sedentary than their age-matched peers. The association with glucose levels, as a potential mediator, is unclear, ...
    • Longitudinal Brain Changes After Stroke and the Association With Cognitive Decline 

      Aamodt, Eva Birgitte; Lydersen, Stian; Alnæs, Dag; SCHELLHORN, TILL; Saltvedt, Ingvild; Beyer, Mona K.; Håberg, Asta (Peer reviewed; Journal article, 2022)
      Background: Cognitive impairment is common after stroke. So is cortical- and subcortical atrophy, with studies reporting more atrophy in the ipsilesional hemisphere than the contralesional hemisphere. The current study ...
    • My husband is not ill; He has memory loss - Caregivers perspectives on health care services for persons with dementia 

      Granbo, Randi; Boulton, Elisabeth; Saltvedt, Ingvild; Helbostad, Jorunn L.; Taraldsen, Kristin (Journal article; Peer reviewed, 2019)
      Background To explore informal caregivers’ perspectives and perceived needs related to health care services/activities for older adults with dementia, in order to understand barriers and facilitators to participation. The ...
    • Neopterin and kynurenic acid as predictors of stroke recurrence and mortality: a multicentre prospective cohort study on biomarkers of inflammation measured three months after ischemic stroke 

      Alme, Katinka Nordheim; Ulvik, Arve; Askim, Torunn; Assmus, Jörg; Mollnes, Tom Eirik; Naik, Mala; Næss, Halvor; Saltvedt, Ingvild; Ueland, Per-Magne; Knapskog, Anne Brita (Peer reviewed; Journal article, 2021)
      Background Chronic low-grade inflammation is associated with both ischemic stroke and sedentary behaviour. The aim of this study was to investigate the predictive abilities of biomarkers of inflammation and immune modulation ...
    • Physical Performance and Cognition as Predictors of Instrumental Activities of Daily Living After Stroke: A Prospective Multicenter Cohort Study 

      Einstad, Marte Stine; Thingstad, Pernille; Lydersen, Stian; Gunnes, Mari; Saltvedt, Ingvild; Askim, Torunn (Journal article; Peer reviewed, 2022)
      Objective: To investigate whether cognition and physical performance, both separately and combined, 3 months post stroke predict change in instrumental activities of daily living (IADL) up to 18 months and whether different ...
    • Predicting the Emergence of Major Neurocognitive Disorder Within Three Months After a Stroke 

      Aamodt, Eva Birgitte; SCHELLHORN, TILL; Stage, Edwin; Sanjay, Apoorva Bharthur; Logan, Paige E.; Svaldi, Diana Otero; Apostolova, Liana G.; Saltvedt, Ingvild; Beyer, Mona Kristiansen (Peer reviewed; Journal article, 2021)
      Background: Neurocognitive disorder (NCD) is common after stroke, with major NCD appearing in about 10% of survivors of a first-ever stroke. We aimed to classify clinical- and imaging factors related to rapid development ...
    • Team approach: Multidisciplinary treatment of hip fractures in elderly patients: Orthogeriatric care 

      Figved, Wender; Myrstad, Marius; Saltvedt, Ingvild; Finjarn, Merete; Odland, Liv Marie Flaten; Frihagen, Frede Jon (Journal article; Peer reviewed, 2019)
      Patients with hip fractures are best managed by a multidisciplinary team. The multidisciplinary team consists of an orthogeriatrician, orthopaedic surgeon, aanesthesiologist, orthopaedic and/or geriatric nurse, occupational ...
    • The association between vascular factors and subjective memory impairment in older people : the HUNT study, Norway 

      Langballe, Ellen Melbye; Tambs, Kristian; Saltvedt, Ingvild; Midthjell, Kristian; Holmen, Jostein (Journal article; Peer reviewed, 2012)
      Objectives: Subjective memory impairment (SMI) is often considered an early sign of dementia. This study investigates the relationship between SMI and dementia-related vascular factors in older people. Method: This study ...