Browsing Publikasjoner fra Cristin - St. Olavs hospital by Author "Kaasa, Stein"
Now showing items 1-16 of 16
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An in-hospital clinical care pathway with integrated decision support for cancer pain management reduced pain intensity and needs for hospital stay
Løhre, Erik Torbjørn; Thronæs, Morten; Brunelli, Cinzia; Kaasa, Stein; Klepstad, Pål (Journal article; Peer reviewed, 2019)Purpose A clinical care pathway for pain management in a palliative care unit was studied with outcomes related to patients, physicians, and health care service. Mandatory use of patient-reported outcome measures (PROMs) ... -
Development and course of chronic widespread pain: the role of time and pain characteristics (the HUNT pain study)
Landmark, Tormod; Romundstad, Pål Richard; Butler, Stephen; Kaasa, Stein; Borchgrevink, Petter Chr. (Journal article; Peer reviewed, 2019)Chronic widespread pain (CWP) is common and associated with loss of functioning and health. Subjects with chronic nonwidespread pain (CnWP) are at increased risk of developing CWP, but few studies have described the nature ... -
ESPEN practical guideline: Clinical Nutrition in cancer
Muscaritoli, Maurizio; Arends, Jann; Bachmann, Patrick; Baracos, Vickie E.; Barthelemy, Nicole; Bertz, Hartmut; Bozzetti, Federico; Hütterer, Elisabeth; Isenring, Elizabeth; Kaasa, Stein; Krznaric, Zeljko; Laird, Barry J.A.; Larsson, Maria; Laviano, Alessandro; Mühlebach, Stefan; Oldervoll, Line Merethe; Ravasco, Paula; Solheim, Tora S; Strasser, Florian; van Bokhorst- De van der Schue, M; Preiser, Jean-Charles; Bischoff, Stephan C. (Peer reviewed; Journal article, 2021)Background This practical guideline is based on the current scientific ESPEN guidelines on nutrition in cancer patients. Methods ESPEN guidelines have been shortened and transformed into flow charts for easier use in ... -
An exploratory study examining the relationship between performance status and systemic inflammation frameworks and cytokine profiles in patients with advanced cancer
Dolan, Ross D.; Laird, Barry J.A.; Klepstad, Pål; Kaasa, Stein; Horgan, Paul G.; Paulsen, Ørnulf; McMillan, Donald C. (Peer reviewed; Journal article, 2019)The role of cytokines in the systemic inflammatory response (SIR) is now well established. This is in keeping with the role of the SIR in tumorigenesis, malignant spread, and the development of cachexia. However, the ... -
Food intake by Patient-Generated Subjective Global Assessment (PG-SGA) corresponds to energy and protein intake as well as weight change in patients with advanced cancer
Bye, Asta; Meli, Kari; Solheim, Tora Skeidsvoll; Laird, Barry J; Kaasa, Stein; Stene, Guro Birgitte; Balstad, Trude Rakel (Journal article; Peer reviewed, 2019)Background & aims The aim of this study was to test how well the Patient-Generated Subjective Global Assessment (PG-SGA) question about food intake correlates with a well-established measurement of food intake. Furthermore, ... -
Fully Integrated Oncology and Palliative Care Services at a Local Hospital in Mid-Norway: Development and Operation of an Innovative Care Delivery Model
Brenne, Anne-Tove; Knudsen, Anne Kari; Raj, Sunil Xavier; Skjelvan, Laila Strand; Lund, Jo-Åsmund; Thronæs, Morten; Løhre, Erik Torbjørn; Hågensen, Liv Ågot; Brunelli, Cinzia; Kaasa, Stein (Peer reviewed; Journal article, 2020)Introduction Early access to cancer palliative care is recommended. Descriptions of structures and processes of outpatient palliative care clinics operated within smaller hospitals are scarce. This paper presents the ... -
Implementing a Standardized Care Pathway Integrating Oncology, Palliative Care and Community Care in a Rural Region of Mid-Norway
Brenne, Anne-Tove; Løhre, Erik T; Knudsen, Anne Kari; Thronæs, Morten; Lund, Jo-Åsmund; Kongshaug, Nina; Neverdal, Marte Nilssen; Rystad, Kristina Edvardsen; Johansen, Marianne Haug; Braseth, Tone Inga; Kaasa, Stein (Peer reviewed; Journal article, 2021)Introduction To improve quality across levels of care, we developed a standardized care pathway (SCP) integrating palliative and oncology services for hospitalized and home-dwelling palliative cancer patients in a rural ... -
Is there a genetic cause of appetite loss? - An explorative study in 1853 cancer patients
Solheim, Tora Skeidsvoll; Fayers, Peter; Fladvad, Torill; Tan, Ben; Skorpen, Frank; Fearon, Kenneth C.; Baracos, Vickie; Klepstad, Pål; Strasser, Florian; Kaasa, Stein (Journal article; Peer reviewed, 2012)Background Appetite loss has a major impact on cancer patients. It is exceedingly prevalent, is a prognostic indicator and is associated with inferior quality of life. Cachexia is a multi‐factorial syndrome defined by a ... -
Mild to Moderate Cognitive Impairment Does Not Affect the Ability to Self-Report Important Symptoms in Patients With Cancer: A Prospective Longitudinal Multinational Study (EPCCS)
Ekström, Magnus P.; Palmqvist, Sebastian; Currow, David C.; Sjøgren, Per; Kurita, Geana Paula; Jakobsen, Gunnhild; Kaasa, Stein; Hjermstad, Marianne Jensen (Peer reviewed; Journal article, 2020)Context Patients with advanced cancer commonly suffer from both distressing symptoms and cognitive impairment, but the effect of cognitive impairment on the reliability and validity of symptom self-report is unknown. ... -
PALLiON - PALLiative care Integrated in ONcology: Study protocol for a Norwegian national cluster-randomized control trial with a complex intervention of early integration of palliative care
Hjermstad, Marianne Jensen; Aass, Nina Kathrine; Andersen, Sigve; Brunelli, Cinzia; Dajani, Olav; Ahmed, Herish; Hamre, Hanne Mari; Haukland, Ellinor Christin; Holmberg, Mats; Jordal, Frode; Krogstad, Hilde; Lundeby, Tonje; Løhre, Erik T; Mjåland, Svein; Nordbø, Arve; Paulsen, Ørnulf; Staff, Erik Schistad; Wester, Torunn; Kaasa, Stein; Loge, Jon Håvard (Peer reviewed; Journal article, 2020)Background - Several publications have addressed the need for a systematic integration of oncological care focused on the tumor and palliative care (PC) focused on the patient with cancer. The exponential increase in ... -
Physical function endpoints in cancer cachexia clinical trials: Systematic Review 1 of the cachexia endpoints series
McDonald, James; Sayers, Judith; Anker, Stefan D.; Arends, Jann; Balstad, Trude Rakel; Baracos, Vickie; Brown, Leo; Bye, Asta; Dajani, Olav; Dolan, Ross; Fallon, Marie T.; Fraser, Eilidh; Griel, Christine; Grzyb, Aleksandra; Hjermstad, Marianne Jensen; Jamal-Hanjani, Mariam; Jakobsen, Gunnhild; Kaasa, Stein; McMillan, Donald; Maddocks, Matthew; Philips, Iain; Ottestad, Inger; Reid, Kieran F.; Sousa, Mariana S.; Simpson, Melanie Rae; Vagnildhaug, Ola Magne; Skipworth, Richard J. E.; Solheim, Tora S; Laird, Barry J (Peer reviewed; Journal article, 2023)In cancer cachexia trials, measures of physical function are commonly used as endpoints. For drug trials to obtain regulatory approval, efficacy in physical function endpoints may be needed alongside other measures. However, ... -
Physical rehabilitation in patients with head and neck cancer: Impact on health-related quality of life and suitability of a post-treatment program
Sandmæl, Jon Arne; Bye, Asta; Solheim, Tora S; Balstad, Trude Rakel; Thorsen, Lene; Skovlund, Eva; Kaasa, Stein; Lund, Jo-Åsmund; Oldervoll, Line Merethe (Peer reviewed; Journal article, 2020)Objective: Physical rehabilitation programs hold the potential to mitigate deterioration in health-related quality of life (HRQoL) in patients with head and neck cancer. The objective was to assess development in relevant ... -
Power comparisons and clinical meaning of outcome measures in assessing treatment effect in cancer cachexia: secondary analysis from a randomised pilot multimodal intervention trial
Balstad, Trude Rakel; Brunelli, Cinzia; Pettersen, Caroline Hild; Schønberg, Svanhild Margrethe Arentz; Skorpen, Frank; Fallon, Marie T.; Kaasa, Stein; Bye, Asta; Laird, Barry J. A.; Stene, Guro Birgitte; Solheim, Tora Skeidsvoll (Peer reviewed; Journal article, 2020)Background: New clinical trials in cancer cachexia are essential and outcome measures with high responsiveness to detect meaningful changes are crucial. This secondary analysis from a multimodal intervention trial estimates ... -
Supporting carers: health care professionals in need of system improvements and education - a qualitative study
Røen, Ingebrigt; Stifoss-Hanssen, Hans; Grande, Gunn; Kaasa, Stein; Sand, Kari; Knudsen, Anne Kari (Journal article; Peer reviewed, 2019)Background: Health care professionals should prevent and relieve suffering in carers of patients with advanced cancer. Despite known positive effects of systematic carer support, carers still do not receive sufficient ... -
Trajectory of health-related quality of life during the last year of life in patients with advanced non-small–cell lung cancer
Kristensen, Are Korsnes; Grønberg, Bjørn Henning; Fløtten, Øystein; Kaasa, Stein; Solheim, Tora S (Peer reviewed; Journal article, 2022)Background The aims of this study were to assess the trajectory of health-related quality of life (HRQOL) during the last year of life in patients with advanced non-small–cell lung cancer (NSCLC) and to explore when and ... -
Zopiclone versus placebo for short-term treatment of insomnia in patients with advanced cancer-a double-blind, randomized placebo-controlled clinical multicenter phase IV trial
Jakobsen, Gunnhild; Sjue, Karin; Paulsen, Ørnulf; Kaasa, Stein; Hjermstad, Marianne Jensen; Klepstad, Pål (Peer reviewed; Journal article, 2022)Purpose: Insomnia is frequent in patients with advanced cancer, and a variety of pharmacological agents is used to treat this condition. Still, few clinical trials have investigated the effectiveness of pharmacological ...