Browsing Publikasjoner fra Cristin - St. Olavs hospital by Author "Abdollahi, Pegah"
Now showing items 1-3 of 3
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Highly expressed genes in multiple myeloma cells – what can they tell us about the disease?
Børset, Magne; Elsaadi, Samah; Vandsemb, Esten Nymoen; Hess, Eli Svorkdal; Steiro, Ida Johnsen; Cócera Fernández, Miguel; Sponaas, Anne-Marit; Abdollahi, Pegah (Peer reviewed; Journal article, 2022)Cancer cells can convert proto-oncoproteins into oncoproteins by increasing the expression of genes that are oncogenic when expressed at high levels. Such genes can promote oncogenesis without being mutated. To find ... -
Phosphatases of regenerating liver are key regulators of metabolism in cancer cells - role of Serine/Glycine metabolism
Abdollahi, Pegah; Vandsemb, Esten Nymoen; Børset, Magne (Peer reviewed; Journal article, 2022)Purpose of review Phosphatases of regenerating liver (PRL) are dual-specificity phosphatases and comprise three members, PRL-1, -2 and -3. Despite the importance of PRLs as oncoproteins, there is no consensus function ... -
PRL-3 induces a positive signaling circuit between glycolysis and activation of STAT1/2
Vandsemb, Esten; Rye, Morten Beck; Steiro, Ida Johnsen; Elsaadi, Samah; Rø, Torstein Baade; Slørdahl, Tobias Schmidt; Sponaas, Anne-Marit; Børset, Magne; Abdollahi, Pegah (Peer reviewed; Journal article, 2021)Multiple myeloma (MM) is an incurable hematologic malignancy resulting from the clonal expansion of plasma cells. MM cells are interacting with components of the bone marrow microenvironment such as cytokines to survive ...