Now showing items 873-892 of 1631

    • Large scale plasma proteomics identifies novel proteins and protein networks associated with heart failure development 

      Shah, Amil M.; Myhre, Peder Langeland; Arthur, Victoria; Dorbala, Pranav; Rasheed, Humaira; Buckley, Leo F.; Claggett, Brian; Liu, Guning; Ma, Jianzhong; Nguyen, Ngoc Quynh; Matsushita, Kunihiro; Ndumele, Chiadi; Tin, Adrienne; Hveem, Kristian; Jonasson, Christian; Dalen, Håvard; Boerwinkle, Eric; Hoogeveen, Ron C.; Ballantyne, Christie; Coresh, Josef; Omland, Torbjørn; Yu, Bing (Peer reviewed; Journal article, 2024)
      Heart failure (HF) causes substantial morbidity and mortality but its pathobiology is incompletely understood. The proteome is a promising intermediate phenotype for discovery of novel mechanisms. We measured 4877 plasma ...
    • Late-onset sepsis in very preterm infants in Norway in 2009-2018: A population-based study 

      Huncikova, Zuzana; Vatne, Anlaug; Stensvold, Hans Jørgen; Lang, Astri Maria; Støen, Ragnhild; Brigtsen, Anne Karin; Salvesen, Bodil; Øymar, Knut Asbjørn Alexander; Rønnestad, Arild Erland; Klingenberg, Claus Andreas (Peer reviewed; Journal article, 2023)
      Objective To evaluate epidemiology and outcomes among very preterm infants (<32 weeks’ gestation) with culture-positive and culture-negative late-onset sepsis (LOS). Design Cohort study using a nationwide, population-based ...
    • Learning the effects of psychotropic drugs during pregnancy using real-world safety data: a paradigm shift toward modern pharmacovigilance 

      Lupattelli, Angela; Spigset, Olav; Nordeng, Hedvig Marie Egeland (Peer reviewed; Journal article, 2018)
      The growing evidence on psychotropic drug safety in pregnancy has been possible thanks to the increasing availability of real-world data, i.e. data not collected in conventional randomised controlled trials. Use of these ...
    • Left-Ventricular Volume Estimation in Contrast-Enhanced Echocardiography Using Deep Learning 

      Hu, Jieyu; Smistad, Erik; Grenne, Bjørnar Leangen; Holte, Espen; Dalen, Håvard; Løvstakken, Lasse (Chapter, 2023)
      Accurate estimation of left ventricular (LV) volume is important for the diagnosis and management of cardiac disease. Contrast-enhanced ultrasound (CEUS) helps improve the visualization of the endocardial borders and is ...
    • Legemiddelavvik hos pasienter innlagt i sykehus. 

      Skeie, Hanne Robbestad; Nordlund, Ragnhild; Slørdal, Lars; Spigset, Olav (Peer reviewed; Journal article, 2021)
      BAKGRUNN Avvik i bruk og håndtering av legemidler er ikke uvanlig. Det finnes lite oppdatert informasjon om legemiddelavvik i norske sykehus. MATERIALE OG METODE Alle uønskede hendelser ved St. Olavs hospital er pålagt ...
    • Leishmaniasis i Norge 

      Muller, Karl Erik; Blomberg, Bjørn; Tellevik, Marit Gjerde; Jensenius, Mogens; Fladeby, Cathrine; Lier, Tore; Sand, Geir; Hannula, Raisa; Langeland, Nina; Mørch, Kristine (Peer reviewed; Journal article, 2021)
      BAKGRUNN - Leishmaniasis er en sjelden, men potensielt alvorlig tropisk infeksjonssykdom. Norske klinikere er lite kjent med diagnostikk og behandling av denne sykdommen. Formålet med studien var å undersøke forekomst, ...
    • Levator ani muscle morphology and function in women with obstetric anal sphincter injury 

      Volløyhaug, Ingrid; Taithongchai, Annika; van Gruting, Isabelle; Sultan, Abdul; Thakar, Ranee (Peer reviewed; Journal article, 2019)
      Objectives To estimate the prevalence of, and explore the risk factors for, levator ani muscle (LAM) injury in women with clinically diagnosed obstetric anal sphincter injury (OASI). The secondary aim was to assess the ...
    • Lifestyle predictors of successful aging: A 20-year prospective HUNT study 

      Bosnes, Ingunn; Nordahl, Hans Morten; Stordal, Eystein; Bosnes, Ole; Myklebust, Tor Åge; Almkvist, Ove (Journal article; Peer reviewed, 2019)
      Background Lifestyle factors predicting successful aging as a unified concept or as separate components of successful aging are important for understanding healthy aging, interventions and preventions. The main objective ...
    • The liminal landscape of mentoring - Stories of physicians becoming mentors 

      Valestrand, Eivind Alexander; Hokstad, Leif Martin; Schei, Edvin; Ofstad, Eirik Hugaas; Stenfors, Terese; Kvernenes, Monika (Peer reviewed; Journal article, 2023)
      Introduction This study explores narratives of physicians negotiating liminality while becoming and being mentors for medical students. Liminality is the unstable phase of a learning trajectory in which one leaves behind ...
    • Limited effect of red blood cell transfusion on long-term mortality among anaemic cardiac surgery patients 

      Tran, Long; Greiff, Guri; Wahba, Alexander; Pleym, Hilde; Videm, Vibeke (Peer reviewed; Journal article, 2020)
      OBJECTIVES Our goal was to investigate long-term mortality associated with red blood cell (RBC) transfusion among patients with anaemia undergoing cardiac surgery when adjusting for known risk factors. METHODS Adults with ...
    • Lipid Levels During Adult Lifetime in Men and Women With and Without a Subsequent Incident Myocardial Infarction: A Longitudinal Analysis of Data From the Tromsø Study 1974 to 2016 

      Albrektsen, Grethe; Wilsgaard, Tom; Heuch, Ivar; Løchen, Maja-Lisa; Thelle, Dag Steinar; Njølstad, Inger; Grimsgaard, Sameline; Bønaa, Kaare Harald (Peer reviewed; Journal article, 2023)
      Background The atherosclerotic effect of an adverse lipid profile is assumed to accumulate throughout life, leading to increased risk of myocardial infarction (MI). Still, little is known about age at onset and duration ...
    • Lipoprotein subfraction profiling in the search of new risk markers for myocardial infarction: The HUNT study 

      Sperstad, Sigri Bakken; Sæther, Julie Caroline; Klevjer, Marie; Giskeødegård, Guro F.; Bathen, Tone Frost; Røsbjørgen, Ragnhild; Dalen, Håvard; Bye, Anja (Peer reviewed; Journal article, 2023)
      Background Traditional biomarkers used to measure risk of myocardial infarction (MI) only explain a modest proportion of the incidence. Lipoprotein subfractions have the potential to improve risk prediction of MI. Aim We ...
    • Liquid Biopsies in Solid Cancers: Implementation in a Nordic Healthcare System 

      Nordgård, Oddmund; Forthun, Rakel Brendsdal; Lapin, Morten; Grønberg, Bjørn Henning; Kalland, Karl Henning; Kopperud, Reidun Kristin; Thomsen, Liv Cecilie Vestrheim; Tjensvoll, Kjersti; Gilje, Bjørnar; Gjertsen, Bjørn Tore; Hovland, Randi (Peer reviewed; Journal article, 2021)
      Liquid biopsies have emerged as a potential new diagnostic tool, providing detailed information relevant for characterization and treatment of solid cancers. We here present an overview of current evidence supporting the ...
    • Livestock-Associated MRSA CC1 in Norway; Introduction to Pig Farms, Zoonotic Transmission, and Eradication 

      Elstrøm, Petter; Grøntvedt, Carl Andreas; Gabrielsen, Christina; Stegger, Marc; Angen, Øystein; Åmdal, Solfrid; Enger, Hege; Urdahl, Anne Margrete; Jore, Solveig; Steinbakk, Martin; Sunde, Marianne (Peer reviewed; Journal article, 2019)
      Farm animals have been identified as an emerging reservoir for transmission of livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) to humans. The low incidence of MRSA in humans and farm animals in ...
    • Livmorhalsprøvetaking i primærhelsetjenesten 

      Gjerde, Priyanthi Borgen; Tollånes, Mette Christophersen; Tropé, Ameli Ellen Claesdotter; Eide, Maj Liv; Natvik, Marianne; Puntervoll, Hanne Eknes (Peer reviewed; Journal article, 2023)
      BAKGRUNN I Norge ble det i 2020 tatt ca. 360 000 screeningprøver fra livmorhals, hvorav 11 000 ble registrert som uegnede. Vi ønsket derfor å undersøke kunnskap om livmorhalsprøvetaking blant leger i primærhelsetjeneste ...
    • Lokal bruk av traneksamsyre som blødningsprofylakse 

      Ausen, Kjersti; Pleym, Hilde; Spigset, Olav (Peer reviewed; Journal article, 2023)
    • Long term effects of an integrated care intervention on hospital utilization in patients with severe COPD: A single centre controlled study 

      Titova, Elena Valerevna; Steinshamn, Sigurd Loe; Indredavik, Bent; Henriksen, Anne Hildur (Journal article; Peer reviewed, 2015)
      Chronic obstructive pulmonary disease (COPD) is one of the main causes of morbidity and mortality globally. In Trondheim in 2008 an integrated care model (COPD-Home) consisting of an education program, self-management plan, ...
    • Long term survival and local control outcomes from single dose targeted intraoperative radiotherapy during lumpectomy (TARGIT-IORT) for early breast cancer: TARGIT-A randomised clinical trial 

      Vaidya, Jayant S; Bulsara, Max; Baum, Michael; Wenz, Frederik; Massarut, Samuele; Pigorsch, Steffi; Alvarado, Michael; Douek, Michael; Saunders, Christobel; Flyger, Henrik; Eiermann, Wolfgang; Brew-Graves, Chris; Williams, Norman R; Potyka, Ingrid; Roberts, Nicholas; Bernstein, Marcelle; Brown, Douglas; Sperk, Elena; Laws, Siobhan; Sütterlin, Marc; Corica, Tammy; Lundgren, Steinar; Holmes, Dennis; Vinante, Lorenzo; Bozza, Fernando; Pazos, Montserrat; Le Blanc-Onfroy, Magali; Gruber, Günther; Polkowski, Wojciech; Dedes, Konstantin J; Niewald, Marcus; Blohmer, Jens; McCready, David; Hoefer, Richard; Kelemen, Pond; Petralia, Gloria; Falzon, Mary; Joseph, David J; Tobias, Jeffrey S (Peer reviewed; Journal article, 2020)
      Objective To determine whether risk adapted intraoperative radiotherapy, delivered as a single dose during lumpectomy, can effectively replace postoperative whole breast external beam radiotherapy for early breast ...
    • Long term trends of breast cancer incidence according to proliferation status 

      Klæstad, Elise; Opdahl, Signe; Raj, Sunil Xavier; Valla, Marit; Bofin, Anna M. (Peer reviewed; Journal article, 2022)
      Background Long-term breast cancer incidence trends according to proliferation status are poorly described. We studied time-trends in breast cancer incidence, using mitotic count and Ki-67 as markers of proliferation. ...
    • Long-term cardiac effects of modern treatment for Hodgkin’s lymphoma 

      Bjerring, Anders W.; Smeland, Knut Bjøro; Stokke, Thomas Muri; Haugaa, Kristina Ingrid Helena Hermann; Holte, Espen; Rösner, Assami; Kiserud, Cecilie E.; Edvardsen, Thor; Sarvari, Sebastian (Journal article; Peer reviewed, 2024)
      Background Hodgkin’s lymphoma (HL) is a hematological malignancy that affects both children and young adults. Traditional treatment is associated with a life-time prevalence of cardiac disease exceeding 50%. In the late ...