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dc.contributor.authorGade, Inger Lise
dc.contributor.authorBrækkan, Sigrid Kufaas
dc.contributor.authorNæss, Inger Anne
dc.contributor.authorHansen, John-Bjarne
dc.contributor.authorCannegieter, Suzanne C.
dc.contributor.authorRosendaal, Frits Richard
dc.contributor.authorOvervad, Kim
dc.contributor.authorHindberg, Kristian
dc.contributor.authorHammerstrøm, Jens
dc.contributor.authorGran, Olga Vikhammer
dc.contributor.authorTjønneland, Anne
dc.contributor.authorSeverinsen, Marianne T.
dc.contributor.authorKristensen, Søren R
dc.identifier.citationTH Open. 2018, 2 (2), .nb_NO
dc.description.abstractThe risk of venous thromboembolism (VTE) in patients who survive the first years after a cancer diagnosis after the acute effects of disease and treatment in comparison to a similar background population has been sparsely investigated. The aim of the study was to investigate if incidence rates (IRs) of VTE differed in patients who were alive at least 2 years after a cancer diagnosis without VTE compared with cancer-free references in a population-based cohort study. The study entry was 2 years after a first cancer diagnosis. For each cancer-exposed subject, five reference subjects were identified within the cohort. The IRs were calculated as number of VTEs per 1,000 person years (×10−3 p-y) in total and in distinct cancer types and corresponding reference subjects. Incidence rate ratios (IRRs) were calculated by Poisson's regression. During a mean follow-up of 5.3 years, 110 VTEs occurred among the 7,288 cancer-exposed subjects and 321 VTEs occurred among the 36,297 identified reference subjects. The IR of VTE was higher for cancer-exposed subjects compared with reference subjects, IRs 3.7 × 10−3 p-y, 95% CI: 3.1 to 4.5 and 1.9 × 10−3 p-y, 95% CI: 1.7 to 2.2, respectively. IRs of VTE in most solid cancer types declined to almost the same level as in the reference subjects 2 years after cancer diagnosis, but remained higher in hematological cancers, IRR 4.0, 95% CI: 2.0 to 7.8.nb_NO
dc.rightsNavngivelse 4.0 Internasjonal*
dc.titleLong-Term Incidence of Venous Thromboembolism in Cancer: The Scandinavian Thrombosis and Cancer Cohortnb_NO
dc.typeJournal articlenb_NO
dc.typePeer reviewednb_NO
dc.source.journalTH Opennb_NO
dc.description.localcode2018 Open Access. CC-BY 4.0nb_NO
cristin.unitnameInstitutt for klinisk og molekylær medisin

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Navngivelse 4.0 Internasjonal
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