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dc.contributor.authorBetancor, Mónica B.
dc.contributor.authorLi, Keshuai
dc.contributor.authorBucerzan, Valentin S.
dc.contributor.authorSprague, Matthew
dc.contributor.authorSayanova, Olga
dc.contributor.authorUsher, Sarah
dc.contributor.authorHan, Lihua
dc.contributor.authorNorambuena, Fernando
dc.contributor.authorTorrissen, Ole
dc.contributor.authorNapier, Johnathan A.
dc.contributor.authorTocher, Douglas R.
dc.contributor.authorOlsen, Rolf Erik
dc.date.accessioned2019-02-26T13:30:21Z
dc.date.available2019-02-26T13:30:21Z
dc.date.created2018-07-02T16:08:18Z
dc.date.issued2018
dc.identifier.citationBritish Journal of Nutrition. 2018, 119 (12), 1378-1392.nb_NO
dc.identifier.issn0007-1145
dc.identifier.urihttp://hdl.handle.net/11250/2587530
dc.description.abstractFacing a bottleneck in the growth of aquaculture, and a gap in the supply and demand of the highly beneficial n-3 long-chain PUFA (LC-PUFA), sustainable alternatives to traditional marine-based feeds are required. Therefore, in the present trial, a novel oil obtained from a genetically engineered oilseed crop, Camelina sativa, that supplied over 25 % n-3 LC-PUFA was tested as a sole dietary-added lipid source in Atlantic salmon (Salmo salar) feed. Three groups of fish were fed three experimental diets for 12 weeks with the same basal composition and containing 20 % added oil supplied by either a blend of fish oil and rapeseed oil (1:3) (COM) reflecting current commercial formulations, wild-type Camelina oil (WCO) or the novel transgenic Camelina oil (TCO). There were no negative effects on the growth, survival rate or health of the fish. The whole fish and flesh n-3 LC-PUFA levels were highest in fish fed TCO, with levels more than 2-fold higher compared with those of fish fed the COM and WCO diets, respectively. Diet TCO had no negative impacts on the evaluated immune and physiological parameters of head kidney monocytes. The transcriptomic responses of liver and mid-intestine showed only mild effects on metabolism genes. Overall, the results clearly indicated that the oil from transgenic Camelina was highly efficient in supplying n-3 LC-PUFA providing levels double that obtained with a current commercial standard, and similar to those a decade ago before substantial dietary fishmeal and oil replacement.nb_NO
dc.language.isoengnb_NO
dc.publisherCambridgenb_NO
dc.titleOil from transgenic Camelina sativa containing over 25 % n-3 long-chain PUFA as the major lipid source in feed for Atlantic salmon (Salmo salar)nb_NO
dc.typeJournal articlenb_NO
dc.typePeer reviewednb_NO
dc.description.versionacceptedVersionnb_NO
dc.source.pagenumber1378-1392nb_NO
dc.source.volume119nb_NO
dc.source.journalBritish Journal of Nutritionnb_NO
dc.source.issue12nb_NO
dc.identifier.doi10.1017/S0007114518001125
dc.identifier.cristin1595280
dc.relation.projectNorges forskningsråd: 245327nb_NO
dc.description.localcodeThis article has been accepted for publication in British Journal of Nutrition . This version is free to view and download for private research and study only. Not for re-distribution, re-sale or use in derivative works. © The Authors 2018nb_NO
cristin.unitcode194,66,10,0
cristin.unitnameInstitutt for biologi
cristin.ispublishedtrue
cristin.fulltextpostprint
cristin.qualitycode1


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