Vis enkel innførsel

dc.contributor.authorHabberstad, Ragnhild H
dc.contributor.authorHjermstad, Marianne Jensen
dc.contributor.authorBrunelli, Cinzia
dc.contributor.authorKaasa, Stein
dc.contributor.authorBennett, Michael I
dc.contributor.authorPardon, Koen
dc.contributor.authorKlepstad, Pål
dc.date.accessioned2019-01-17T11:55:58Z
dc.date.available2019-01-17T11:55:58Z
dc.date.created2018-09-26T15:31:28Z
dc.date.issued2018
dc.identifier.citationSupportive Care in Cancer. 2018, 1-9.nb_NO
dc.identifier.issn0941-4355
dc.identifier.urihttp://hdl.handle.net/11250/2581057
dc.description.abstractPurpose Explore clinical factors associated with higher pain intensity and future pain in patients with bone metastases to identify patients who can benefit from closer follow-up or pain-modifying interventions. Methods This is a secondary analysis of 606 patients with bone metastases included in a multicenter longitudinal study. The dependent variables were “average pain” and “worst pain” in the last 24 h (0–10 NRS). Twenty independent variables with potential association to pain intensity were selected based on previous literature. Cross-sectional analyses were performed with multiple linear regression to explore factors associated with pain intensity at baseline. Longitudinal data were analyzed with a generalized equation models to explore current factors associated with pain intensity at the next visit in 1 month. Results Current pain intensity (p < 0.001), sleep disturbances (p 0.01 and 0.006), drowsiness (p 0.003 and 0.033) and male gender (p 0.045 and 0.001) were associated with higher average and worst pain intensity in 1 month. In addition, breakthrough pain was related to higher worst pain intensity (p 0.003) in 1 month. The same variables were also associated with higher average pain intensity at baseline. Conclusion Higher current pain intensity, sleep disturbances, drowsiness, male gender, and breakthrough pain are factors associated with higher pain intensity in patients with bone metastases at the next follow-up in 1 month. These factors should be assessed in clinical practice and may aid clinicians in identifying patients that can benefit from closer follow-up or interventions to prevent lack of future pain control.nb_NO
dc.language.isoengnb_NO
dc.publisherSpringer Verlagnb_NO
dc.titleWhich factors can aid clinicians to identify a risk of pain during the following month in patients with bone metastases? A longitudinal analysesnb_NO
dc.typeJournal articlenb_NO
dc.typePeer reviewednb_NO
dc.description.versionacceptedVersionnb_NO
dc.source.pagenumber1-9nb_NO
dc.source.journalSupportive Care in Cancernb_NO
dc.identifier.doi10.1007/s00520-018-4405-9
dc.identifier.cristin1614206
dc.description.localcodeThis is a post-peer-review, pre-copyedit version of an article published in [Supportive Care in Cancer] Locked until 13.8.2019 due to copyright restrictions. The final authenticated version is available online at: https://doi.org/10.1007/s00520-018-4405-9nb_NO
cristin.unitcode194,65,15,0
cristin.unitcode194,65,25,0
cristin.unitnameInstitutt for klinisk og molekylær medisin
cristin.unitnameInstitutt for sirkulasjon og bildediagnostikk
cristin.ispublishedtrue
cristin.fulltextpostprint
cristin.qualitycode1


Tilhørende fil(er)

Thumbnail

Denne innførselen finnes i følgende samling(er)

Vis enkel innførsel