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dc.contributor.authorGong, Yi
dc.contributor.authorWang, Mao
dc.contributor.authorHe, Jianying
dc.date.accessioned2018-11-21T06:57:27Z
dc.date.available2018-11-21T06:57:27Z
dc.date.created2016-10-03T10:16:43Z
dc.date.issued2016
dc.identifier.citationRSC Advances. 2016, 6 (97), 95067-95072.nb_NO
dc.identifier.issn2046-2069
dc.identifier.urihttp://hdl.handle.net/11250/2574035
dc.description.abstractA bottom-up approach was empolyed to prepare colloidosomes with dual-level controlled permeability. Starting from the monodisperse poly-2,2,2-trilfuoroethyl methacrylate (PTFMA) core, different size of microgels were obtained by introducing varying thickness of the Poly(N-isopropylacrylamide) (P(NIPAM-co-AAc)) shell. The effects of core on the mechanical property of microgels and their behavior at oil/water interface in Mickering emulsion were carefully studied. The colloidosomes were then obtained by the “locking” the interfaical microgels in the Mickering emulsion. The release of model drug FITC-Dex from colloidosomes was examined in selected media and the controllable release was achieved by pH (coarse level) and the ratio of the shell to core in the microgels (fine level). The dual-level controlled permeability of colloidosomes enables the high precision for pH triggered drug release system. It is the first demonstration on the permeability control of colloidosomes can be achieved by size control on shell and core of microgels owing to the core hydrophobicity and the shell hydrophilicity. Both convenience and precision on permeability control of colloidosomes were improved in this way due to the mature size control technology in the microgels synthesis.nb_NO
dc.language.isoengnb_NO
dc.publisherRoyal Society of Chemistrynb_NO
dc.titleThe behavior of hydrophobic-core/hydrophilic-shell structured microgels at an interface: From Mickering emulsion to colloidosomes with dual-level controlled permeabilitynb_NO
dc.typeJournal articlenb_NO
dc.typePeer reviewednb_NO
dc.description.versionpublishedVersionnb_NO
dc.source.pagenumber95067-95072nb_NO
dc.source.volume6nb_NO
dc.source.journalRSC Advancesnb_NO
dc.source.issue97nb_NO
dc.identifier.doi10.1039/c6ra18215a
dc.identifier.cristin1388920
dc.relation.projectNorges forskningsråd: 245963nb_NO
dc.relation.projectNorges forskningsråd: 234626nb_NO
dc.relation.projectNorges forskningsråd: 228599nb_NO
dc.description.localcodeOpen Access. Published by Royal Society of Chemistry.nb_NO
cristin.unitcode194,64,45,0
cristin.unitnameInstitutt for konstruksjonsteknikk
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode1


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