Vis enkel innførsel

dc.contributor.authorMoser, May-Britt
dc.contributor.authorRowland, David Clayton
dc.contributor.authorMoser, Edvard Ingjald
dc.date.accessioned2018-05-23T11:58:22Z
dc.date.available2018-05-23T11:58:22Z
dc.date.created2016-01-25T15:51:48Z
dc.date.issued2015
dc.identifier.issn1943-0264
dc.identifier.urihttp://hdl.handle.net/11250/2498921
dc.description.abstractThe hippocampal system is critical for storage and retrieval of declarative memories, including memories for locations and events that take place at those locations. Spatial memories place high demands on capacity. Memories must be distinct to be recalled without interference and encoding must be fast. Recent studies have indicated that hippocampal networks allow for fast storage of large quantities of uncorrelated spatial information. The aim of the this article is to review and discuss some of this work, taking as a starting point the discovery of multiple functionally specialized cell types of the hippocampal–entorhinal circuit, such as place, grid, and border cells. We will show that grid cells provide the hippocampus with a metric, as well as a putative mechanism for decorrelation of representations, that the formation of environment-specific place maps depends on mechanisms for long-term plasticity in the hippocampus, and that long-term spatiotemporal memory storage may depend on offline consolidation processes related to sharp-wave ripple activity in the hippocampus. The multitude of representations generated through interactions between a variety of functionally specialized cell types in the entorhinal–hippocampal circuit may be at the heart of the mechanism for declarative memory formation.nb_NO
dc.language.isoengnb_NO
dc.publisherCold Spring Harbor Laboratory Pressnb_NO
dc.titlePlace cells, grid cells, and memorynb_NO
dc.typeJournal articlenb_NO
dc.typePeer reviewednb_NO
dc.description.versionpublishedVersionnb_NO
dc.source.volume7nb_NO
dc.source.journalCold Spring Harbor Perspectives in Biologynb_NO
dc.source.issue2nb_NO
dc.identifier.doi10.1101/cshperspect.a021808
dc.identifier.cristin1322010
dc.relation.projectNorges forskningsråd: 10414800nb_NO
dc.description.localcodeCopyright (c) 2015 Cold Spring Harbor Laboratory Press; all rights reserved; doi: 10.1101/cshperspect.a021808 Cite this article as Cold Spring Harb Perspect Biol 2015;7:a021808nb_NO
cristin.unitcode194,65,60,0
cristin.unitnameKavliinstitutt for nevrovitenskap
cristin.ispublishedtrue
cristin.fulltextpostprint
cristin.qualitycode1


Tilhørende fil(er)

Thumbnail

Denne innførselen finnes i følgende samling(er)

Vis enkel innførsel