Vis enkel innførsel

dc.contributor.authorSnekvik, Ingrid
dc.contributor.authorSmith, Catherine H.
dc.contributor.authorNilsen, Tom Ivar Lund
dc.contributor.authorLangan, Sinéad M.
dc.contributor.authorModalsli, Ellen Heilmann
dc.contributor.authorRomundstad, Pål Richard
dc.contributor.authorSaunes, Marit
dc.date.accessioned2018-01-23T09:49:28Z
dc.date.available2018-01-23T09:49:28Z
dc.date.created2017-12-22T10:10:27Z
dc.date.issued2017
dc.identifier.citationJournal of Investigative Dermatology. 2017, 137 (12), 2484-2490.nb_NO
dc.identifier.issn0022-202X
dc.identifier.urihttp://hdl.handle.net/11250/2478965
dc.description.abstractAlthough psoriasis has been associated with obesity, there are few prospective studies with objective measures. We prospectively examined the effect of body mass index, waist circumference, waist-hip ratio, and 10-year weight change on the risk of developing psoriasis among 33,734 people in the population-based Nord-Trøndelag Health Study (i.e., HUNT), Norway. During follow-up, 369 incident psoriasis cases occurred. Relative risk (RR) of psoriasis was estimated by Cox regression. One standard deviation higher body mass index, waist circumference, and waist-hip ratio gave RRs of 1.22 (95% confidence interval [CI] = 1.11–1.34), 1.26 (95% CI = 1.15–1.39), and 1.18 (95% CI = 1.07–1.31), respectively. Compared with normal weight participants, obese people had an RR of 1.87 (95% CI = 1.38–2.52), whereas comparing the fourth with the first quartile of waist circumference gave an RR of 1.95 (95% CI = 1.46–2.61). One standard deviation higher weight change gave an RR of 1.20 (95% CI = 1.07–1.35), and people who increased their body weight by 10 kg or more had an RR of 1.72 (95% CI = 1.15–2.58) compared with being weight stable. In conclusion, obesity and high abdominal fat mass doubles the risk of psoriasis, and long-term weight gain substantially increases psoriasis risk. Preventing weight gain and promoting maintenance of a normal body weight could reduce incidence of psoriasis.nb_NO
dc.language.isoengnb_NO
dc.publisherElseviernb_NO
dc.rightsNavngivelse 4.0 Internasjonal*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/deed.no*
dc.titleObesity, waist circumference, weight change, and risk of incident psoriasis: prospective data from the HUNT studynb_NO
dc.typeJournal articlenb_NO
dc.typePeer reviewednb_NO
dc.description.versionpublishedVersionnb_NO
dc.source.pagenumber2484-2490nb_NO
dc.source.volume137nb_NO
dc.source.journalJournal of Investigative Dermatologynb_NO
dc.source.issue12nb_NO
dc.identifier.doi10.1016/j.jid.2017.07.822
dc.identifier.cristin1531364
dc.description.localcode© 2017 The Authors. Published by Elsevier, Inc. on behalf of the Society for Investigative Dermatology. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).nb_NO
cristin.unitcode194,65,20,0
cristin.unitcode194,65,15,0
cristin.unitnameInstitutt for samfunnsmedisin og sykepleie
cristin.unitnameInstitutt for klinisk og molekylær medisin
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode2


Tilhørende fil(er)

Thumbnail

Denne innførselen finnes i følgende samling(er)

Vis enkel innførsel

Navngivelse 4.0 Internasjonal
Med mindre annet er angitt, så er denne innførselen lisensiert som Navngivelse 4.0 Internasjonal