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dc.contributor.authorOlsen, Grethe Mari
dc.contributor.authorOhara, Shinya
dc.contributor.authorIijima, Toshio
dc.contributor.authorWitter, Menno
dc.date.accessioned2018-01-18T13:31:13Z
dc.date.available2018-01-18T13:31:13Z
dc.date.created2017-12-12T14:45:26Z
dc.date.issued2017
dc.identifier.citationHippocampus. 2017, 27 (4), 335–358.nb_NO
dc.identifier.issn1050-9631
dc.identifier.urihttp://hdl.handle.net/11250/2478173
dc.description.abstractThe posterior parietal cortex has been implicated in spatial functions, including navigation. The hippocampal and parahippocampal region and the retrosplenial cortex are crucially involved in navigational processes and connections between the parahippocampal/retrosplenial domain and the posterior parietal cortex have been described. However, an integrated account of the organization of these connections is lacking. Here, we investigated parahippocampal connections of each posterior parietal subdivision and the neighboring secondary visual cortex using conventional retrograde and anterograde tracers as well as transsynaptic retrograde tracing with a modified rabies virus. The results show that posterior parietal as well as secondary visual cortex entertain overall sparse connections with the parahippocampal region but not with the hippocampal formation. The medial and lateral dorsal subdivisions of posterior parietal cortex receive sparse input from deep layers of all parahippocampal areas. Conversely, all posterior parietal subdivisions project moderately to dorsal presubiculum, whereas rostral perirhinal cortex, postrhinal cortex, caudal entorhinal cortex and parasubiculum all receive sparse posterior parietal input. This indicated that the presubiculum might be a major liaison between parietal and parahippocampal domains. In view of the close association of the presubiculum with the retrosplenial cortex, we included the latter in our analysis. Our data indicate that posterior parietal cortex is moderately connected with the retrosplenial cortex, particularly with rostral area 30. The relative sparseness of the connectivity with the parahippocampal and retrosplenial domains suggests that posterior parietal cortex is only a modest actor in forming spatial representations underlying navigation and spatial memory in parahippocampal and retrosplenial cortex.nb_NO
dc.language.isoengnb_NO
dc.publisherWileynb_NO
dc.titleParahippocampal and retrosplenial connections of rat posterior parietal cortexnb_NO
dc.typeJournal articlenb_NO
dc.typePeer reviewednb_NO
dc.description.versionacceptedVersionnb_NO
dc.source.pagenumber335–358nb_NO
dc.source.volume27nb_NO
dc.source.journalHippocampusnb_NO
dc.source.issue4nb_NO
dc.identifier.doi10.1002/hipo.22701
dc.identifier.cristin1526338
dc.description.localcode© 2017 Wiley Periodicals, Inc.This is the peer reviewed version of the article, which has been published in final form at http://dx.doi.org/10.1002/hipo.22701. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.nb_NO
cristin.unitcode194,65,60,0
cristin.unitnameKavliinstitutt for nevrovitenskap
cristin.ispublishedtrue
cristin.fulltextpostprint
cristin.qualitycode1


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