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dc.contributor.authorHoydal, Katrin Sunniva
dc.contributor.authorStyrishave, Bjarne
dc.contributor.authorCiesielski, Tomasz Maciej
dc.contributor.authorLetcher, Robert J.
dc.contributor.authorDam, Maria
dc.contributor.authorJenssen, Bjørn Munro
dc.date.accessioned2017-12-07T08:51:50Z
dc.date.available2017-12-07T08:51:50Z
dc.date.created2017-10-09T11:05:23Z
dc.date.issued2017
dc.identifier.citationEnvironmental Research. 2017, 159 613-621.nb_NO
dc.identifier.issn0013-9351
dc.identifier.urihttp://hdl.handle.net/11250/2469495
dc.description.abstractPersistent organic pollutants (POPs) are known to have endocrine disruptive effects, interfering with endogenous steroid hormones. The present study examined nine steroid hormones and their relationships with the concentrations of selected POPs in pilot whales (Globicephala melas) from the Faroe Islands, NE Atlantic. The different steroids were detected in 15 to all of the 26 individuals. High concentrations of progesterone (83.3–211.7 pmol/g) and pregnenolone (PRE; 4.68–5.69 pmol/g) were found in three adult females indicating that they were pregnant or ovulating. High androgen concentrations in two of the males reflected that one was adult and that one (possibly) had reached puberty. In males a significant positive and strong correlation between body length and testosterone (TS) levels was identified. Furthermore, positive and significant correlations were found between 4-OH-CB107/4’-OH-CB108 and 17β-estradiol in males. In adult females significant positive correlations were identified between PRE and CB149 and t-nonachlor, between estrone and CB138, -149, -187 and p,p’-DDE, between androstenedione and CB187, and between TS and CB-99 and -153. Although relationships between the POPs and the steroid hormones reported herein are not evidence of cause-effect relationships, the positive correlations between steroids and POPs, particularly in females, suggest that POPs may have some endocrine disrupting effects on the steroid homeostasis in this species.nb_NO
dc.language.isoengnb_NO
dc.publisherElseviernb_NO
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internasjonal*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/deed.no*
dc.titleSteroids hormones and persistent organic pollutants in plasma from North-eastern Atlantic pilot whalesnb_NO
dc.typeJournal articlenb_NO
dc.typePeer reviewednb_NO
dc.description.versionacceptedVersionnb_NO
dc.source.pagenumber613-621nb_NO
dc.source.volume159nb_NO
dc.source.journalEnvironmental Researchnb_NO
dc.identifier.doi10.1016/j.envres.2017.09.003
dc.identifier.cristin1503277
dc.description.localcode© 2017. This is the authors’ accepted and refereed manuscript to the article. LOCKED until 14.9.2019 due to copyright restrictions. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/nb_NO
cristin.unitcode194,66,10,0
cristin.unitnameInstitutt for biologi
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode2


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Attribution-NonCommercial-NoDerivatives 4.0 Internasjonal
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