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Risk assessment of "other substances" – L-phenylalanine and DL-phenylalanine. Opinion of the Panel on Nutrition, Dietetic Products, Novel Food and Allergy of the Norwegian Scientific Committee for Food Safety

Frøyland, Livar; Haugen, Margaretha; Holvik, Kristin; Løvik, Martinus; Strand, Tor A; Tell, Grethe S.; Iversen, Per Ole
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Fr%C3%B8yland_2016_Ris.pdf (925.6Kb)
URI
http://hdl.handle.net/11250/2461198
Date
2016
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  • Institutt for klinisk og molekylær medisin [2072]
  • Publikasjoner fra CRIStin - NTNU [21000]
Abstract
At the request from the Norwegian Food Safety Authority (NFSA), the Norwegian Scientific Committee on Food Safety (VKM) has characterised the risk of specified doses of Lphenylalanine and DL-phenylalanine in food supplements. VKM concludes that:

• In adults (≥ 18 years), the specified doses 100, 250, 500, 750 and 1000 mg/day Lphenylalanine in food supplements are considered unlikely to cause adverse health effects.

• In adolescents (14 to < 18 years), the specified doses 100, 250, 500, 750 and 1000 mg/day L-phenylalanine in food supplements are considered unlikely to cause adverse health effects.

• In children (10 to < 14 years), the specified doses 100, 250, 500, 750 and 1000 mg/day L-phenylalanine in food supplements are considered unlikely to cause adverse health effects. Although the highest dose provides 23 mg/kg bw per day which slightly exceeds 22.4 mg/kg bw per day, it is considered unlikely to cause adverse health effects in healthy children 10 to < 14 years.

• None of the above conclusions are applicable for patients with phenylketonuria (PKU).

• No conclusion can be made regarding DL-phenylalanine
Publisher
Norwegian Committee for Food Safety
Series
VKM Report;

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