dc.contributor.author | Bruzell, Ellen Merete | |
dc.contributor.author | Granum, Berit | |
dc.contributor.author | Hetland, Ragna Bogen | |
dc.contributor.author | Husøy, Trine | |
dc.contributor.author | Rohloff, Jens | |
dc.contributor.author | Wicklund, Trude | |
dc.contributor.author | Steffensen, Inger-Lise | |
dc.date.accessioned | 2017-10-20T06:11:15Z | |
dc.date.available | 2017-10-20T06:11:15Z | |
dc.date.created | 2017-10-19T12:51:57Z | |
dc.date.issued | 2015 | |
dc.identifier.isbn | 978-82-8259-179-9 | |
dc.identifier.uri | http://hdl.handle.net/11250/2461127 | |
dc.description.abstract | The Norwegian Scientific Committee for Food Safety (VKM) has, at the request of the Norwegian Food Safety Authority (NFSA), assessed the risk of 1500 mg/day of L-carnitine and 2250 mg/day of L-carnitine-L-tartrate in food supplements. L-carnitine occurs naturally in foods and is endogenously synthesised. L-carnitine-L-tartrate is synthesised commercially, and it dissociates into L-carnitine and tartaric acid in the gastrointestinal tract.
Based on the included literature there was no evidence indicating that age affects sensitivity towards L-carnitine, L-carnitine-L-tartrate or tartaric acid. Therefore, in this risk characterisation the same tolerance level as for adults was assumed for children and adolescents (adjusted for body weight).
VKM concludes that a dose of 1500 mg of L-carnitine per day, which is equivalent to a dose of 2250 mg of L-carnitine-L-tartrate per day, is unlikely to cause adverse health effects in adolescents (14 to <18 years), whereas intake at this level in children (10 to < 14 years) may represent a risk of adverse health effects. The tartaric acid exposure from this dose of L-carnitine-L-tartrate is unlikely to cause adverse health effects. | nb_NO |
dc.language.iso | eng | nb_NO |
dc.publisher | Norwegian Scientific Committee for Food Safety (VKM) | nb_NO |
dc.relation.ispartof | VKM Report | |
dc.relation.ispartofseries | VKM Report; | |
dc.relation.uri | https://vkm.no/risikovurderinger/allevurderinger/andrestoffer/lkarnitinogllarnitinltartratikosttilskudd.4.761cd04215dabef8a9e83d3b.html | |
dc.title | Risk assessment of "other substances" – L-Carnitine and L-Carnitine-L-tartrate. Opinion of the Panel on Food Additives, Flavourings, Processing Aids, Materials in Contact with Food and Cosmetics of the Norwegian Scientific Committee for Food Safety | nb_NO |
dc.type | Research report | nb_NO |
dc.description.version | publishedVersion | nb_NO |
dc.source.pagenumber | 47 | nb_NO |
dc.source.issue | 2015:24 | nb_NO |
dc.identifier.cristin | 1505919 | |
cristin.unitcode | 194,66,10,0 | |
cristin.unitname | Institutt for biologi | |
cristin.ispublished | true | |
cristin.fulltext | original | |