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Scientific Opinion on application (EFSA-GMO-NL-2010-77) for the placing on the market of herbicide-tolerant genetically modified cotton GHB614 × LLCotton25 for food and feed uses, import and processing under Regulation (EC) No 1829/2003 from Bayer CropScience

Arpaia, Salvatore; Birch, Nicholas; Chesson, Andrew; du Jardin, Patrick; Gathmann, Achim; Gropp, Jürgen; Herman, Lieve; Hoen-Sorteberg, Hilde-Gunn; Jones, Huw; Kiss, József; Kleter, Gijs; Løvik, Martinus; Messean, Antoine; Naegeli, Hanspeter; Nielsen, Kåre Magne; Ovesna, Jaroslava; Perry, Joe; Rostoks, Nils; Tebbe, Christoph
Peer reviewed
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article78094.pdf (382.2Kb)
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http://hdl.handle.net/11250/2381882
Utgivelsesdato
2014
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  • Institutt for klinisk og molekylær medisin [2072]
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Originalversjon
EFSA Journal 2014, 12(5):3680   10.2903/j.efsa.2014.3680
Sammendrag
Cotton GHB614 × LLCotton25 was produced by conventional crossing. The EFSA GMO Panel previously

assessed the two single cotton events GHB614 and LLCotton25 and did not identify safety concerns. Integrity of

the inserts was retained in the two -event stack cotton. No differences requiring further food and feed safety

assessment were identified in the compositional analysis of cotton GHB614 × LLCotton25 except for a higher

level of gossypol. The EFSA GMO Panel further assessed this difference and considers that it is of no safety

relevance for animals and humans. Expression analysis and safety assessment of the newly express ed proteins

identified no concerns regarding their potential toxicity and allergenicity. No indications of safety issues

regarding the overall allergenicity of cotton GHB614 × LLCotton25 were identified. There are no indications of

an increased likelihood of establishment and spread of feral cotton plants. Considering the scope of the

application, potential interactions of cotton GHB614 × LLCotton25 with the biotic and abiotic environment were

not considered a relevant issue. Environmental risks associated with an unlikely but theoretically possible

horizontal gene transfer from cotton GHB614 × LLCotton25 to bacteria have not been identified. The postmarket environmental monitoring plan and reporting intervals are in line with the intended uses of cotton

GHB614 × LLCotton25.
Utgiver
European Food Safety Authority (EFSA)
Tidsskrift
EFSA Journal

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