Synthesis of Novel Homo-N-Nucleoside Analogs Composed of a Homo-1,4-Dioxane Sugar Analog and Substituted 1,3,5-Triazine Base Equivalents
Journal article, Peer reviewed
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Date
2008Metadata
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- Institutt for kjemi [1345]
- Publikasjoner fra CRIStin - NTNU [36890]
Abstract
Enantioselective syntheses from dimethyl tartrate of 1,3,5-triazine homo-Nnucleoside
analogs, containing a 1,4-dioxane moiety replacing the sugar unit in natural
nucleosides, were accomplished. The triazine heterocycle in the nucleoside analogs was
further substituted with combinations of NH2, OH and Cl in the 2,4-triazine positions.