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dc.contributor.authorThomsen, Per Hove
dc.contributor.authorTorp, Nor Christian
dc.contributor.authorDahl, Kitty
dc.contributor.authorChristensen, K
dc.contributor.authorEnglyst, Inger
dc.contributor.authorMelin, Karin
dc.contributor.authorNissen, Judith Becker
dc.contributor.authorValderhaug, Robert
dc.contributor.authorWeidle, Bernhard
dc.contributor.authorSkarphedinsson, Gudmundur Águst
dc.contributor.authorvon bahr, p.l.
dc.contributor.authorIvarsson, Tord
dc.contributor.authorHybel, Katja A.
dc.date.accessioned2015-09-29T11:17:47Z
dc.date.accessioned2015-10-15T08:22:59Z
dc.date.available2015-09-29T11:17:47Z
dc.date.available2015-10-15T08:22:59Z
dc.date.issued2013
dc.identifier.citationChild and Adolescent Psychiatry and Mental Health 2013, 7(1)nb_NO
dc.identifier.issn1753-2000
dc.identifier.urihttp://hdl.handle.net/11250/2356207
dc.description-nb_NO
dc.description.abstractBACKGROUND: This paper describes and discusses the methodology of the Nordic long-term OCD-treatment study (NordLOTS). The purpose of this effectiveness study was to study treatment outcome of CBT, to identify CBT non- or partial responders and to investigate whether an increased number of CBT-sessions or sertraline treatment gives the best outcome; to identify treatment refractory patients and to investigate the outcome of aripiprazole augmentation; to study the outcome over a three year period for each responder including the risk of relapse, and finally to study predictors, moderators and mediators of treatment response. METHODS: Step 1 was an open and uncontrolled clinical trial with CBT, step 2 was a controlled, randomised non-blinded study of CBT non-responders from step 1. Patients were randomized to receive either sertraline plus CBT-support or continued and modified CBT. In step 3 patients who did not respond to either CBT or sertraline were treated with aripiprazole augmentation to sertraline. CONCLUSIONS: This multicenter trial covering three Scandinavian countries is going to be the largest CBT-study for paediatric OCD to date. It is not funded by industry and tries in the short and long-term to answer the question whether further CBT or SSRI is better in CBT non-responders.nb_NO
dc.language.isoengnb_NO
dc.publisherBioMed Centralnb_NO
dc.titleThe Nordic long-term OCD treatment study (NordLOTS): rationale, design, and methodsnb_NO
dc.typeJournal articlenb_NO
dc.typePeer revieweden_GB
dc.date.updated2015-09-29T11:17:47Z
dc.source.volume7nb_NO
dc.source.journalChild and Adolescent Psychiatry and Mental Healthnb_NO
dc.source.issue1nb_NO
dc.identifier.doi10.1186/1753-2000-7-41
dc.identifier.cristin1151830
dc.description.localcode© 2013 Thomsen et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.nb_NO


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