• The fibro- and cyto-architecture demarcating the border between the dentate gyrus and CA3 in sheep (Ovis aries) and domestic pig (Sus scrofa domesticus) 

      Blackstad, Jan Sigurd Beddari; Osen, Kirsten Kjelsberg; Leergaard, Trygve Brauns (Peer reviewed; Journal article, 2022)
      The hippocampal formation is essential for spatial navigation and episodic memory. The anatomical structure is largely similar across mammalian species, apart from the deep polymorphic layer of the dentate gyrus and the ...
    • From the eye to the hippocampal formation: Neural networks as analysis and discovery tools 

      Frey, Markus (Doctoral theses at NTNU;2023:28, Doctoral thesis, 2023)
      Sammendrag Ønsket om å forstå hvordan menneskesinnet fungerer har nådd inn til mange tidligere adskilte fagfelt, som alle jobber sammen i søken etter å løse menneskehjernens mange mysterier. I denne avhandlingen fokuserer ...
    • Functional characterization of the antennal-lobe glomeruli constituting the macro glomerular complex and the posterior complex in the moth brain 

      Kvamvold, R. Eskil. (Master thesis, 2019)
      In order to understand how information is processed in a neural circuit, it is important to have an in-depth overview of all aspects of the circuit. For exploring the coding principles of the antennal lobe (AL), it is ...
    • Functional diversity along the transverse axis of hippocampal area CA1 

      Igarashi, Kei M; Ito, Hiroshi; Moser, Edvard Ingjald; Moser, May-Britt (Journal article; Peer reviewed, 2014)
      Decades of neuroscience research have shed lights on the hippocampus as a key structure for the formation of episodic memory. The hippocampus is divided into distinct subfields – CA1, CA2 and CA3. Whereas accumulating ...
    • Functional network topography of the medial entorhinal cortex 

      Obenhaus, Horst-Andreas; Zong, Weijian; Jacobsen, R. Irene; Rose, Tobias; Donato, Flavio; Chen, Liangyi; Cheng, Heping; Bonhoeffer, Tobias; Moser, May-Britt; Moser, Edvard Ingjald (Journal article; Peer reviewed, 2022)
      The medial entorhinal cortex (MEC) creates a map of local space,based on thefiring patterns of grid, head-direction (HD), border,and object-vector (OV) cells. How these cell types are organizedanatomically is debated. ...
    • Functional organization of the hippocampal longitudinal axis 

      Strange, B; Witter, Menno; Lein, Ed S.; Moser, Edvard Ingjald (Journal article; Peer reviewed, 2014)
      The precise functional role of the hippocampus remains a topic of much debate. The dominant view is that the dorsal (or posterior) hippocampus is implicated in memory and spatial navigation and the ventral (or anterior) ...
    • Functional properties of habenular neurons are determined by developmental stage and sequential neurogenesis 

      Fore, Stephanie Liesbeth; Acuna Hinrichsen, Francisca Daniela; Mutlu, Aytac Kadir; Bartoszek-Kandler, Ewelina Magdalena; Chau, Khac Thanh Phong; Diaz Verdugo, Carmen; Palumbo, Fabrizio; Ringers, Christa; Jurisch-Yaksi, Nathalie; Yaksi, Emre; Serneels, Bram (Peer reviewed; Journal article, 2020)
      The developing brain undergoes drastic alterations. Here, we investigated developmental changes in the habenula, a brain region that mediates behavioral flexibility during learning, social interactions, and aversive ...
    • Functional properties of stellate cells in medial entorhinal cortex layer II 

      Rowland, David Clayton; Obenhaus, Horst-Andreas; Skytøen, Emilie; Zhang, Qiangwei; Kentros, Clifford; Moser, Edvard Ingjald; Moser, May-Britt (Journal article; Peer reviewed, 2018)
      Layer II of the medial entorhinal cortex (MEC) contains two principal cell types: pyramidal cells and stellate cells. Accumulating evidence suggests that these two cell types have distinct molecular profiles, physiological ...
    • Functional segregation in the rat hippocampalentorhinal circuit 

      Lu, Li (Doctoral thesis at NTNU;2015:201, Doctoral thesis, 2015)
      NORSK SAMMENDRAG: Hippocampus-entorhinal systemet spiller en viktig rolle i romlig navigasjon og episodisk hukommelse hos rotter. Stedceller i hippocampus kan kode både romlig og kontekstuell informasjon. Som populasjon ...
    • GABAA receptor subunit α3 in network dynamics in the medial entorhinal cortex 

      Berggaard, Nina; Witter, Menno; van der Want, Johannes Jacobus Leendert (Journal article; Peer reviewed, 2019)
      Layer II of the medial entorhinal cortex (MEC LII) contains the largest number of spatially modulated grid cells and is one of the first regions in the brain to express Alzheimer’s disease (AD)-related pathology. The most ...
    • Generating Neural Networks from Ependymal Cells harvested after Spinal Cord Injury 

      Rem, Marit Trones (Master thesis, 2020)
      Traumatisk ryggmargsskader (tRMS) er preget av alvorlige, irreversible forstyrrelser av lokale og nevrale kretsløp i ryggmargen med ødeleggende effekt som når gjennom de supraspinale kanalene. Som svar på tRMS, blir ...
    • Glia-neuron interactions underlie state transitions to generalized seizures 

      Diaz Verdugo, Carmen; Myren-Svelstad, Sverre; Aydin, Ecem; Van Hoeymissen, Evelien; Deneubourg, Celine; Vanderhaeghe, Silke; Vancraeynest, Julie; Pelgrims, Robbrecht; Casacak, Mehmet Ilyas; Muto, Akira; Kawakami, Koichi; Jurisch-Yaksi, Nathalie; Yaksi, Emre (Journal article; Peer reviewed, 2019)
      Brain activity and connectivity alter drastically during epileptic seizures. The brain networks shift from a balanced resting state to a hyperactive and hypersynchronous state. It is, however, less clear which mechanisms ...
    • The Global Campaign turns 18: a brief review of its activities and achievements 

      Steiner, Timothy J.; Birbeck, Gretchen L.; Jensen, Rigmor H.; Martelletti, Paolo; Stovner, Lars Jacob; Uluduz, Derya; Leonardi, Matilde; Olesen, Jes; Katsarava, Zaza (Peer reviewed; Journal article, 2022)
    • Grid cell dynamics in the medial entorhinal cortex 

      Wernle, Tanja (Doctoral theses at NTNU;2018:206, Doctoral thesis, 2018)
      Gittercelledynamikk i mediale entorhinal cortex Gittercelleaktivitet oppstår momentant når dyr beveger seg gjennom et miljø, og kan dermed være ansvarlig for hjernens posisjonsberegning. For å beregne avstand må ...
    • Grid cells and cortical representation 

      Moser, Edvard Ingjald; Roudi, Yasser; Witter, Menno; Kentros, Clifford; Bonhoeffer, Tobias; Moser, May-Britt (Journal article; Peer reviewed, 2014)
      One of the grand challenges in neuroscience is to comprehend neural computation in the association cortices, the parts of the cortex that have shown the largest expansion and differentiation during mammalian evolution and ...
    • Grid-cell modules remain coordinated when neural activity is dissociated from external sensory cues 

      Waaga, Torgeir; Agmon, Haggai; Normand, Valentin; Nagelhus, Anne; Gardner, Richard; Moser, May-Britt; Moser, Edvard Ingjald; Burak, Yoram (Journal article; Peer reviewed, 2022)
      The representation of an animal’s position in the medial entorhinal cortex (MEC) is distributed across several modules of grid cells, each characterized by a distinct spatial scale. The population activity within each ...
    • Grid-cell representations in mental simulation 

      Bellmund, Jacob Lukas Sarid; Deuker, Lorena; Schröder, Tobias Navarro; Döller, Christian Fritz Andreas (Journal article; Peer reviewed, 2016)
      Anticipating the future is a key motif of the brain, possibly supported by mental simulation of upcoming events. Rodent single-cell recordings suggest the ability of spatially tuned cells to represent subsequent locations. ...
    • Growing gold nanostructures for shape-selective cellular uptake 

      Bandyopadhyay, Sulalit; McDonagh, Birgitte Hjelmeland; Singh, Gurvinder; Raghunathan, Karthik; Sandvig, Axel; Sandvig, Ioanna; Andreassen, Jens-Petter; Glomm, Wilhelm (Journal article; Peer reviewed, 2018)
      With development in the synthesis of shape- and size-dependent gold (Au) nanostructures (NSs) and their applications in nanomedicine, one of the biggest challenges is to understand the interaction of these shapes with ...
    • Gustatory-mediated avoidance of bacterial lipopolysaccharides via TRPA1 activation in Drosophila 

      Soldano, Alessia; Alpizar, Yeranddy A; Boonen, Brett; Franco, Luis; Lopez-Requena, Alejandro; Liu, Guangda; Mora, Natalia; Yaksi, Emre; Voets, Thomas; Vennekens, Rudi; Hassan, Bassem A; Talavera, Karel (Journal article; Peer reviewed, 2016)
      Detecting pathogens and mounting immune responses upon infection is crucial for animal health. However, these responses come at a high metabolic price (McKean and Lazzaro, 2011, Kominsky et al., 2010), and avoiding pathogens ...
    • Head direction maps remain stable despite grid map fragmentation 

      Whitlock, Jonathan Robert; Derdikman, Dori Moshe (Journal article; Peer reviewed, 2012)
      Areas encoding space in the brain contain both representations of position (place cells and grid cells) and representations of azimuth (head direction cells). Previous studies have already suggested that although grid cells ...