Blar i Institutt for sirkulasjon og bildediagnostikk på tidsskrift "PLOS ONE"
Viser treff 1-20 av 27
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A balanced tissue composition reveals new metabolic and gene expression markers in prostate cancer
(Journal article; Peer reviewed, 2016)Molecular analysis of patient tissue samples is essential to characterize the in vivo variability in human cancers which are not accessible in cell-lines or animal models. This applies particularly to studies of tumor ... -
Accuracy of heart rate watches: Implications for weight management
(Peer reviewed; Journal article, 2016)Background Wrist-worn monitors claim to provide accurate measures of heart rate and energy expenditure. People wishing to lose weight use these devices to monitor energy balance, however the accuracy of these devices ... -
Airway segmentation and centerline extraction from thoracic CT - Comparison of a new method to state of the art commercialized methods
(Peer reviewed; Journal article, 2015)Introduction Our motivation is increased bronchoscopic diagnostic yield and optimized preparation, for navigated bronchoscopy. In navigated bronchoscopy, virtual 3D airway visualization is often used to guide a bronchoscopic ... -
The association between normal lung function and peak oxygen uptake in patients with exercise intolerance and coronary artery disease
(Peer reviewed; Journal article, 2020)In coronary artery disease (CAD), exercise intolerance with reduced oxygen uptake at peak exercise (VO2peak) is assumed to primarily reflect cardiovascular limitation. However, oxygen transport and utilization depends on ... -
The bidirectional association between depressive symptoms, assessed by the HADS, and albuminuria-A longitudinal population-based cohort study with repeated measures from the HUNT2 and HUNT3 Study
(Peer reviewed; Journal article, 2022)Background Both albuminuria and depression are associated with cardiovascular disease, reflecting low-grade systemic inflammation and endothelial dysfunction. They share risk factors including weight, blood pressure, ... -
Can functional walk tests add value to the prediction of cardiorespiratory fitness after stroke? A prospective cohort study
(Journal article; Peer reviewed, 2021)Background Cardiorespiratory fitness is often impaired following stroke, and peak oxygen consumption (VO2peak) is an important prognostic value of all-cause mortality. The primary objective was to investigate whether ... -
Comparing the impact of vaccination strategies on the spread of COVID-19, including a novel household-targeted vaccination strategy
(Peer reviewed; Journal article, 2022)With limited availability of vaccines, an efficient use of the limited supply of vaccines in order to achieve herd immunity will be an important tool to combat the wide-spread prevalence of COVID-19. Here, we compare a ... -
Consent is a confounding factor in a prospective observational study of critically ill elderly patients
(Peer reviewed; Journal article, 2022)During analysis of a prospective multinational observation study of critically ill patients ≥80 years of age, the VIP2 study, we also studied the effects of differences in country consent for study inclusion. This is a ... -
Do weather changes influence physical activity level among older adults? – The Generation 100 study
(Journal article; Peer reviewed, 2018)Introduction Understanding how individual and environmental factors impact physical activity (PA) level is important when building strategies to improve PA of older adults. No studies have examined how hour-to-hour weather ... -
Early diagnosis of sepsis in emergency departments, time to treatment, and association with mortality: An observational study
(Journal article; Peer reviewed, 2020)Background Early recognition of sepsis is critical for timely initiation of treatment. The first objective of this study was to assess the timeliness of diagnostic procedures for recognizing sepsis in emergency departments. ... -
Exploring the diagnostic potential of adding T2 dependence in diffusion-weighted MR imaging of the prostate
(Peer reviewed; Journal article, 2021)Background: Magnetic resonance imaging (MRI) is essential in the detection and staging of prostate cancer. However, improved tools to distinguish between low-risk and high-risk cancer are needed in order to select the ... -
FunHoP analysis reveals upregulation of mitochondrial genes in prostate cancer
(Peer reviewed; Journal article, 2022)Mitochondrial activity in cancer cells has been central to cancer research since Otto Warburg first published his thesis on the topic in 1956. Although Warburg proposed that oxidative phosphorylation in the tricarboxylic ... -
Incidence and risk factors for major bleeding among patients undergoing percutaneous coronary intervention: Findings from the Norwegian Coronary Stent Trial (NORSTENT)
(Peer reviewed; Journal article, 2021)Introduction Bleeding is a concern after percutaneous coronary intervention (PCI) and subsequent dual antiplatelet therapy (DAPT). We herein report the incidence and risk factors for major bleeding in the Norwegian Coronary ... -
Incidence, recurring admissions and mortality of severe bacterial infections and sepsis over a 22-year period in the population-based HUNT study
(Peer reviewed; Journal article, 2022)Purpose Severe bacterial infections are important causes of hospitalization and loss of health worldwide. In this study we aim to characterize the total burden, recurrence and severity of bacterial infections in the ... -
Inhaled nitric oxide as temporary respiratory stabilization in patients with COVID-19 related respiratory failure (INOCOV): Study protocol for a randomized controlled trial
(Peer reviewed; Journal article, 2022)Background In March 2020, WHO announced the COVID-19 a pandemic and a major global public health emergency. Mortality from COVID-19 is rapidly increasing globally, with acute respiratory failure as the predominant cause ... -
Innate immune signalling genetics of pain, cognitive dysfunction and sickness symptoms in cancer pain patients treated with transdermal fentanyl
(Peer reviewed; Journal article, 2015)Common adverse symptoms of cancer and chemotherapy are a major health burden; chief among these is pain, with opioids including transdermal fentanyl the mainstay of treatment. Innate immune activation has been implicated ... -
Lipoprotein subfraction profiling in the search of new risk markers for myocardial infarction: The HUNT study
(Peer reviewed; Journal article, 2023)Background Traditional biomarkers used to measure risk of myocardial infarction (MI) only explain a modest proportion of the incidence. Lipoprotein subfractions have the potential to improve risk prediction of MI. Aim We ... -
Lung function and peak oxygen uptake in chronic obstructive pulmonary disease phenotypes with and without emphysema
(Journal article; Peer reviewed, 2021)Previous studies of associations of forced expiratory lung volume in one second (FEV1) with peak oxygen uptake (VO2peak) in chronic obstructive pulmonary disease (COPD) have not taken sex, age and height related variance ... -
Non-Smoking tobacco affects endothelial function in healthy men in one of the largest health studies ever performed; the nord-trøndelag health study in Norway; HUNT3
(Peer reviewed; Journal article, 2016)Background Oral tobacco (snuff) is taking a large market share in Scandinavia, especially with young users. However, long-term health effects are unknown. Small studies show association between snuff and reduced endothelial ... -
Predicting VO2peak from Submaximal- and Peak Exercise Models: The HUNT 3 Fitness Study, Norway
(Peer reviewed; Journal article, 2016)Purpose Peak oxygen uptake (VO2peak) is seldom assessed in health care settings although being inversely linked to cardiovascular risk and all-cause mortality. The aim of this study was to develop VO2peak prediction ...