Blar i Institutt for sirkulasjon og bildediagnostikk på tidsskrift "OncoTarget"
Viser treff 1-4 av 4
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A novel non-canonical Wnt signature for prostate cancer aggressiveness
(Journal article; Peer reviewed, 2016)Activation of the Canonical Wnt pathway (CWP) has been linked to advanced and metastatic prostate cancer, whereas the Wnt5a-induced non-canonical Wnt pathway (NCWP) has been associated with both good and poor prognosis. A ... -
APIM-peptide targeting PCNA improves the efficacy of docetaxel treatment in the TRAMP mouse model of prostate cancer
(Journal article; Peer reviewed, 2018)Docetaxel is the chemotherapeutic choice for metastatic hormone-refractory prostate cancer, however, it only marginally improves the survival rate. The purpose of the present study was to examine if a peptide ... -
Inhibition of O-GlcNAc transferase activity reprograms prostate cancer cell metabolism
(Journal article; Peer reviewed, 2016)Metabolic networks are highly connected and complex, but a single enzyme, O-GlcNAc transferase (OGT) can sense the availability of metabolites and also modify target proteins. We show that inhibition of OGT activity inhibits ... -
Presence of TMPRSS2-ERG is associated with alterations of the metabolic profile in human prostate cancer
(Journal article; Peer reviewed, 2016)TMPRSS2-ERG has been proposed to be a prognostic marker for prostate cancer. The aim of this study was to identify changes in metabolism, genes and biochemical recurrence related to TMPRSS2-ERG by using an integrated ...