Blar i Institutt for samfunnsmedisin og sykepleie på forfatter "Valla, Marit"

Viser treff 1-11 av 11

    • The association of women’s birth size with risk of molecular breast cancer subtypes: a cohort study 

      Sandvei, Marie Søfteland; Opdahl, Signe; Valla, Marit; Lagiou, Pagona; Vesterfjell, Ellen Veronika; Rise, Tor Vikan; Overrein, Tina Syvertsen; Skjervold, Anette Hansen; Engstrøm, Monica J; Bofin, Anna M.; Vatten, Lars J. (Peer reviewed; Journal article, 2021)
      Background: Because birth size appears to be positively associated with breast cancer risk, we have studied whether this risk may differ according to molecular breast cancer subtypes. Methods: A cohort of 22,931 women born ...

    • Basal markers and prognosis in luminal breast cancer 

      Engstrøm, Monica J; Valla, Marit; Bofin, Anna M. (Journal article; Peer reviewed, 2017)
      Purpose Basal marker expression in triple-negative breast cancers identifies basal-like tumours, and thus separates the TN group into two prognostic groups. However, the expression and prognostic significance of basal ...

    • Characterization of FGD5 expression in primary breast cancers and lymph node metastases 

      Valla, Marit; Mjønes, Patricia; Engstrøm, Monica J; Ytterhus, Borgny; Bordin, Diana Lilian; van Loon, Barbara; Akslen, Lars A.; Vatten, Lars Johan; Opdahl, Signe; Bofin, Anna M. (Journal article; Peer reviewed, 2018)
      Faciogenital dysplasia 5 (FGD5) amplification drives tumor cell proliferation, and is present in 9.5% of breast cancers. We describe FGD5 expression, assess associations between FGD5 amplification and FGD5 expression, and ...

    • DTX3 copy number increase in breast cancer: a study of associations to molecular subtype, proliferation and prognosis 

      Valla, Marit; Opdahl, Signe; Ytterhus, Borgny; Bofin, Anna M. (Journal article; Peer reviewed, 2021)
      Purpose The degree of cell proliferation is important for subclassifcation of breast cancers into prognostic and therapeutic groups. DTX3 has been identifed as a driver of proliferation in luminal breast cancer. In this ...

    • FGD5 amplification in breast cancer patients is associated with tumor proliferation and a poorer prognosis 

      Valla, Marit; Engstrøm, Monica J; Ytterhus, Borgny; Hansen, Åse Kristin Skain; Akslen, Lars A.; Vatten, Lars Johan; Opdahl, Signe; Bofin, Anna M. (Journal article; Peer reviewed, 2017)
      Purpose Proliferation is a hallmark of cancer. Using a combined genomic approach, FGD5 amplification has been identified as a driver of proliferation in Luminal breast cancer. We aimed to describe FGD5 copy number change ...

    • Long term trends of breast cancer incidence according to proliferation status 

      Klæstad, Elise; Opdahl, Signe; Raj, Sunil Xavier; Valla, Marit; Bofin, Anna M. (Peer reviewed; Journal article, 2022)
      Background Long-term breast cancer incidence trends according to proliferation status are poorly described. We studied time-trends in breast cancer incidence, using mitotic count and Ki-67 as markers of proliferation. ...

    • Molecular subtypes of breast cancer: incidence and prognosis 

      Valla, Marit (Doctoral theses at NTNU;2017:276, Doctoral thesis, 2017)
      Forekomsten av brystkreft har over flere tiår økt i den vestlige verden, og i Norge har det vært en dobling av insidensen siden Kreftregisteret startet sin overvåkning av antall krefttilfeller i Norge i 1952. I Norge har ...

    • Molecular Subtypes of Breast Cancer: Long-term Incidence Trends and Prognostic Differences 

      Valla, Marit; Vatten, Lars Johan; Engstrøm, Monica J; Haugen, Olav Anton; Akslen, Lars A.; Bjørngaard, Johan Håkon; Hagen, Anne Irene; Ytterhus, Borgny; Bofin, Anna M.; Opdahl, Signe (Journal article; Peer reviewed, 2016)
      Background: Secular trends in incidence and prognosis of molecular breast cancer subtypes are poorly described. We studied long-term trends in a population of Norwegian women born 1886–1977. Methods: A total of 52,949 ...

    • MRPS23 amplification and gene expression in breast cancer; association with proliferation and the non-basal subtypes 

      Klæstad, Elise; Opdahl, Signe; Engstrøm, Monica J; Ytterhus, Borgny; Wik, Elisabeth; Bofin, Anna Mary; Valla, Marit (Peer reviewed; Journal article, 2020)
      Purpose MRPS23 is recognized as a driver of proliferation in luminal breast cancer. The aims of the present study were to describe MRPS23 copy number change in breast cancer, and to assess associations between MRPS23 ...

    • The prognostic value of androgen receptors in breast cancer subtypes 

      Kraby, Maria Ryssdal; Valla, Marit; Opdahl, Signe; Haugen, Olav Anton; Sawicka, Joanna Ewa; Engstrøm, Monica J; Bofin, Anna M. (Journal article; Peer reviewed, 2018)
      Purpose Androgen receptor (AR) expression is frequent in breast cancer and has been associated with good prognosis in several studies. The present study investigates AR-expression in relation to molecular subtypes, ...

    • Visual and digital assessment of Ki-67 in breast cancer tissue - a comparison of methods 

      Skjervold, Anette Hansen; Pettersen, Henrik P Sahlin; Valla, Marit; Opdahl, Signe; Bofin, Anna Mary (Peer reviewed; Journal article, 2022)
      Background In breast cancer (BC) Ki-67 cut-off levels, counting methods and inter- and intraobserver variation are still unresolved. To reduce inter-laboratory differences, it has been proposed that cut-off levels for ...