• Development and course of chronic pain over 4 years in the general population: The HUNT pain study 

      Landmark, Tormod; Dale, Ola; Romundstad, Pål Richard; Woodhouse, Astrid; Kaasa, Stein; Borchgrevink, Petter Chr. (Journal article; Peer reviewed, 2018)
      Background Epidemiological studies of chronic pain frequently report high prevalence estimates. However, there is little information about the development and natural course of chronic pain. Methods We followed a ...
    • Development and course of chronic widespread pain: the role of time and pain characteristics (the HUNT pain study) 

      Landmark, Tormod; Romundstad, Pål Richard; Butler, Stephen; Kaasa, Stein; Borchgrevink, Petter Chr. (Journal article; Peer reviewed, 2019)
      Chronic widespread pain (CWP) is common and associated with loss of functioning and health. Subjects with chronic nonwidespread pain (CnWP) are at increased risk of developing CWP, but few studies have described the nature ...
    • Effect of physical exercise on muscle mass and strength in cancer patients during treatment : A systematic review 

      Stene, Guro Birgitte; Helbostad, Jorunn; Balstad, Trude Rakel; Riphagen, Ingrid Ingeborg; Kaasa, Stein; Oldervoll, Line Merete (Journal article; Peer reviewed, 2013)
      Cancer treatment and its side effects may cause muscle wasting. Physical exercise has the potential to increase muscle mass and strength and to improve physical function in cancer patients undergoing treatment. A systematic ...
    • ESPEN guidelines on nutrition in cancer patients 

      Arends, Jann; Bachmann, Peter; Baracos, Vickie; Barthelemy, N; Bertz, H; Bozzetti, Frederico; Fearon, KC; Hütterer, E; Isenring, E; Kaasa, Stein; Krznaric, Z; Laird, Barry J.; Larsson, M; Laviano, A; Mühlebach, S; Muscaritoli, Maurizio; Oldervoll, Line Merethe; Ravasco, Paula; Solheim, Tora Skeidsvoll; Strasser, Florian; de van der Schueren, Marian; Preiser, JC (Journal article; Peer reviewed, 2017)
      Cancers are among the leading causes of morbidity and mortality worldwide, and the number of new cases is expected to rise significantly over the next decades. At the same time, all types of cancer treatment, such as ...
    • ESPEN practical guideline: Clinical Nutrition in cancer 

      Muscaritoli, Maurizio; Arends, Jann; Bachmann, Patrick; Baracos, Vickie E.; Barthelemy, Nicole; Bertz, Hartmut; Bozzetti, Federico; Hütterer, Elisabeth; Isenring, Elizabeth; Kaasa, Stein; Krznaric, Zeljko; Laird, Barry J.A.; Larsson, Maria; Laviano, Alessandro; Mühlebach, Stefan; Oldervoll, Line Merethe; Ravasco, Paula; Solheim, Tora S; Strasser, Florian; van Bokhorst- De van der Schue, M; Preiser, Jean-Charles; Bischoff, Stephan C. (Peer reviewed; Journal article, 2021)
      Background This practical guideline is based on the current scientific ESPEN guidelines on nutrition in cancer patients. Methods ESPEN guidelines have been shortened and transformed into flow charts for easier use in ...
    • Health-related quality of life in patients with advanced melanoma treated with ipilimumab: prognostic implications and changes during treatment 

      Aamdal, Elin; Skovlund, Eva; Jacobsen, Kari Dolven; Straume, Oddbjørn; Kersten, Christian; Herlofsen, Oluf; Karlsen, Jarle; Hussain, Israr; Amundsen, Anita; Dalhaug, Astrid; Nyakas, Marta Sølvi; Hagene, Kirsten Thorin; Holmsen, Kjersti; Aamdal, Steinar; Kaasa, Stein; Guren, Tormod Kyrre; Kyte, Jon A (Peer reviewed; Journal article, 2022)
      Background We have previously reported that the safety and efficacy of ipilimumab in real-world patients with metastatic melanoma were comparable to clinical trials. Few studies have explored health-related quality of ...
    • Ipilimumab in a real-world population: A prospective Phase IV trial with long-term follow-up 

      Aamdal, Elin; Jacobsen, Kari Dolven; Straume, Oddbjørn; Kersten, Christian; Herlofsen, Oluf; Karlsen, Jarle; Hussain, Israr; Amundsen, Anita; Dalhaug, Astrid; Nyakas, Marta Sølvi; Schuster, Cornelia; Hagene, Kirsten Thorin; Holmsen, Kjersti; Russnes, Hege Elisabeth Giercksky; Skovlund, Eva; Kaasa, Stein; Aamdal, Steinar; Kyte, Jon A.; Guren, Tormod Kyrre (Peer reviewed; Journal article, 2021)
      Ipilimumab was the first treatment that improved survival in advanced melanoma. Efficacy and toxicity in a real-world setting may differ from clinical trials, due to more liberal eligibility criteria and less intensive ...
    • Longitudinal Associations between Exercise and Pain in the General Population - The HUNT Pain Study 

      Landmark, Tormod; Romundstad, Pål Richard; Borchgrevink, Petter Chr.; Kaasa, Stein; Dale, Ola (Journal article; Peer reviewed, 2013)
      Background: Population-based studies have reported conflicting findings on the relationship between physical activity and pain, and most studies reporting a relationship are cross sectional. Temporal relationships are ...
    • Overall survival after initial radiotherapy for brain metastases; a population based study of 2140 patients with non-small cell lung cancer 

      Karlsson, Astrid Telhaug; Hjermstad, Marianne Jensen; Omdahl, Therese; Aass, Nina Kathrine; Skovlund, Eva; Hellebust, Taran Paulsen; Johansen, Safora; Kaasa, Stein; Yri, Olav Erich (Peer reviewed; Journal article, 2021)
      Background Brain metastases (BM) occur in about 30% of all patients with non-small cell lung cancer (NSCLC). BM treatment guidelines recommend more frequent use of stereotactic radiotherapy (SRT). Overall, studies report ...
    • Physical function endpoints in cancer cachexia clinical trials: Systematic Review 1 of the cachexia endpoints series 

      McDonald, James; Sayers, Judith; Anker, Stefan D.; Arends, Jann; Balstad, Trude Rakel; Baracos, Vickie; Brown, Leo; Bye, Asta; Dajani, Olav; Dolan, Ross; Fallon, Marie T.; Fraser, Eilidh; Griel, Christine; Grzyb, Aleksandra; Hjermstad, Marianne Jensen; Jamal-Hanjani, Mariam; Jakobsen, Gunnhild; Kaasa, Stein; McMillan, Donald; Maddocks, Matthew; Philips, Iain; Ottestad, Inger; Reid, Kieran F.; Sousa, Mariana S.; Simpson, Melanie Rae; Vagnildhaug, Ola Magne; Skipworth, Richard J. E.; Solheim, Tora S; Laird, Barry J (Peer reviewed; Journal article, 2023)
      In cancer cachexia trials, measures of physical function are commonly used as endpoints. For drug trials to obtain regulatory approval, efficacy in physical function endpoints may be needed alongside other measures. However, ...
    • Physical rehabilitation in patients with head and neck cancer: Impact on health-related quality of life and suitability of a post-treatment program 

      Sandmæl, Jon Arne; Bye, Asta; Solheim, Tora S; Balstad, Trude Rakel; Thorsen, Lene; Skovlund, Eva; Kaasa, Stein; Lund, Jo-Åsmund; Oldervoll, Line Merethe (Peer reviewed; Journal article, 2020)
      Objective: Physical rehabilitation programs hold the potential to mitigate deterioration in health-related quality of life (HRQoL) in patients with head and neck cancer. The objective was to assess development in relevant ...
    • Preoperative Prognostic Index for Patients with Brain Metastases—A Population-Based Multi-Centre Study 

      Winther, Rebecca Rootwelt; Skovlund, Eva; Andreassen, Joakim Stray; Arvidsson, Lisa; Halvardson, Jonathan; Solheim, Ole Skeidsvoll; Bartek, Jiri; Kaasa, Stein; Hjermstad, Marianne Jensen; Vik-Mo, Einar Osland (Peer reviewed; Journal article, 2023)
      Background: Brain metastases (BM) are common in cancer patients and are associated with high morbidity and mortality. Surgery is an option, but the optimal selection of patients for surgery is challenging and controversial. ...
    • Surgery for brain metastases – real-world prognostic factors’ association with survival 

      Rootwelt, Rebecca; Vik-Mo, Einar Osland; Yri, Olav Erich; Aass, Nina Kathrine; Kaasa, Stein; Skovlund, Eva; Helseth, Eirik; Hjermstad, Marianne Jensen (Journal article, 2021)
      Background Surgical resection of brain metastases (BM) improves overall survival (OS) in selected patients. Selecting those patients likely to benefit from surgery is challenging. The Graded Prognostic Assessment (GPA) ...
    • Surgery for brain metastases—impact of the extent of resection 

      Winther, Rebecca Rootwelt; Hjermstad, Marianne Jensen; Skovlund, Eva; Aass, Nina Kathrine; Helseth, Eirik; Kaasa, Stein; Yri, Olav Erich; Vik-Mo, Einar O. (Peer reviewed; Journal article, 2022)
      Background Surgical resection of brain metastases improves symptoms and survival in selected patients. The benefit of gross total resection is disputed, as most patients are believed to succumb from their non-CNS tumor ...
    • Symptoms in the general Norwegian adult population - prevalence and associated factors 

      Krogstad, Hilde; Loge, Jon Håvard; Grotmol, Kjersti S.; Kaasa, Stein; Kiserud, Cecilie E.; Salvesen, Øyvind; Hjermstad, Marianne Jensen (Peer reviewed; Journal article, 2020)
      Background Patients´ own perceptions and evaluations of symptoms, functioning and other health-related factors, i.e. Patient Reported Outcomes (PROs), are important elements for providing good patient care. Symptoms are ...
    • Usability testing of EirV3-a computer-based tool for patient-reported outcome measures in cancer 

      Krogstad, Hilde; Sundt-Hansen, Stine Marie; Hjermstad, Marianne Jensen; Hågensen, Liv Ågot; Kaasa, Stein; Loge, Jon Håvard; Raj, Sunil Xavier; Steinsbekk, Aslak; Sand, Kari (Journal article, 2018)
      Purpose Eir version 3 (V3) is an electronic tool for administration of patient-reported outcome measures (Eir-Patient) that immediately presents patient scores on the physician’s computer (Eir-Doctor). Perceived usability ...
    • Validation of Doloplus-2 among nonverbal nursing home patients--an evaluation of Doloplus-2 in a clinical setting. 

      Torvik, Karin; Kaasa, Stein; Kirkevold, Øyvind; Saltvedt, Ingvild; Hølen, Jacob C; Fayers, Peter; Rustøen, Tone (Journal article; Peer reviewed, 2010)
      In the present study, more patients were categorized as having pain while using Doloplus-2 compared with nurses' estimation of pain without using any tools. The fact that nurses could not report if the patients were in ...
    • Zopiclone versus placebo for short-term treatment of insomnia in patients with advanced cancer-a double-blind, randomized placebo-controlled clinical multicenter phase IV trial 

      Jakobsen, Gunnhild; Sjue, Karin; Paulsen, Ørnulf; Kaasa, Stein; Hjermstad, Marianne Jensen; Klepstad, Pål (Peer reviewed; Journal article, 2022)
      Purpose: Insomnia is frequent in patients with advanced cancer, and a variety of pharmacological agents is used to treat this condition. Still, few clinical trials have investigated the effectiveness of pharmacological ...