Institutt for nevromedisin og bevegelsesvitenskap: Recent submissions
Now showing items 1-20 of 3370
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Antibodies against SARS-CoV-2 spike protein in the cerebrospinal fluid of COVID‑19 patients and vaccinated controls: a multicentre study
(Peer reviewed; Journal article, 2024)Introduction SARS-CoV-2 antibodies in the cerebrospinal fluid (CSF) of COVID-19 patients possibly reflect blood-cerebrospinal fluid barrier (BCB) disruption due to systemic inflammation. However, some studies indicate ... -
Early systemic insults following traumatic brain injury: association with biomarker profiles, therapy for intracranial hypertension, and neurological outcomes-an analysis of CENTER-TBI data
(Peer reviewed; Journal article, 2024)Purpose: We analysed the impact of early systemic insults (hypoxemia and hypotension, SIs) on brain injury biomarker profiles, acute care requirements during intensive care unit (ICU) stay, and 6-month outcomes in patients ... -
One-year employment outcome prediction after traumatic brain injury: A CENTER-TBI study
(Peer reviewed; Journal article, 2024)Background Traumatic brain injury (TBI) can come with long term consequences for functional outcome that can complicate return to work. Objectives This study aims to make accurate patient-specific predictions on one-year ... -
What predicts citation counts and translational impact in headache research? A machine learning analysis
(Peer reviewed; Journal article, 2024)Background We aimed to develop the first machine learning models to predict citation counts and the translational impact, defined as inclusion in guidelines or policy documents, of headache research, and assess which ... -
Metacognitive Therapy for People Experiencing Persistent Post-Concussion Symptoms Following Mild Traumatic Brain Injury: A Preliminary Multiple Case-Series Study
(Peer reviewed; Journal article, 2024)After mild traumatic brain injury (mTBI), a subgroup of individuals experience persistent post-concussion symptoms (PPCS) that include headaches, cognitive difficulties, and fatigue. The aim of this preliminary study was ... -
Genomic 8-oxoguanine modulates gene transcription independent of its repair by DNA glycosylases OGG1 and MUTYH
(Peer reviewed; Journal article, 2024)8-oxo-7,8-dihydroguanine (OG) is one of the most abundant oxidative lesions in the genome and is associated with genome instability. Its mutagenic potential is counteracted by a concerted action of 8-oxoguanine DNA glycosylase ... -
Dissecting gene expression networks in the developing hippocampus through the lens of NEIL3 depletion
(Peer reviewed; Journal article, 2024)Gene regulation in the hippocampus is fundamental for its development, synaptic plasticity, memory formation, and adaptability. Comparisons of gene expression among different developmental stages, distinct cell types, and ... -
Enhanced glutathione levels confer resistance to apoptotic and ferroptotic programmed cell death in NEIL DNA glycosylase deficient HAP1 cells
(Peer reviewed; Journal article, 2024)The NTHL1 and NEIL1-3 DNA glycosylases are major enzymes in the removal of oxidative DNA base lesions, via the base excision repair (BER) pathway. It is expected that lack of these DNA glycosylases activities would render ... -
Arthroscopic meniscal surgery in Norway from 2010 to 2020: A paradigmatic shift
(Journal article; Peer reviewed, 2024)Purpose: Meniscal injuries in the knee are usually treated surgically with arthroscopic partial resection (APR) or arthroscopic repair (AR). APR has been shown to increase the risk of osteoarthritis and the focus has shifted ... -
Risk of first hip fracture under treatment with zoledronic acid versus alendronate: a NOREPOS cohort study of 88,000 Norwegian men and women in outpatient care
(Journal article; Peer reviewed, 2024)We aimed to investigate the risk of hip fracture associated with zoledronic acid treatment compared to alendronate on a population level. The risk of hip fracture was lower in women using zoledronic acid and higher in women ... -
Contrasting Characteristics and Outcomes of Sports-Related and Non-Sports-Related Traumatic Brain Injury
(Peer reviewed; Journal article, 2024)Importance: Exposure to traumatic brain injury (TBI) has raised widespread concern over participation in sports, particularly over possible long-term consequences. However, little is known about the outcomes of individuals ... -
Effect of a preconception lifestyle intervention, continued throughout pregnancy, on blood pressure in females at high risk of gestational diabetes: Secondary findings from a randomized controlled trial
(Master thesis, 2024)Bakgrunn: Det er viktig å forebygge høyt blodtrykk under graviditet, da dette kan føre til alvorlige komplikasjoner for mor og foster. Disse komplikasjonene inkluderer preeklampsi, svangerskapshypertensjon, eklampsi, for ... -
Change in physical performance during the season in semi-professional male handball players – a longitudinal study
(Master thesis, 2024)Abstrakt Bakgrunn For å prestere best mulig må håndballspillere inneha høye verdier av muskelstyrke, kraft, smidighet og utholdenhet. Imidlertid er kunnskapen om effektene håndballsesongen har på maksimalt oksygenopptak ... -
Is there an association between birth characteristics and fractures in young adults? The HUNT Study, Norway
(Peer reviewed; Journal article, 2025)Summary This population study investigated the association between birth characteristics and fracture risk in 11,099 young adults (aged 19–54 years). Our findings indicate that birth weight, gestational age, and birth ... -
Validation of the European visual field standards for driving: A driving simulator-based study
(Peer reviewed; Journal article, 2024)Purpose To determine whether we could establish evidence-based pass/fail criteria for perimetry in the context of the European visual field standards for driving. Methods This two-centre, cross-sectional study included ... -
Mind the intention-behavior gap: a qualitative study of post-myocardial infarction patients’ beliefs and experiences with long-term supervised and self-monitored physical exercise
(Journal article; Peer reviewed, 2024)Background Many post-myocardial infarction (MI) patients struggle with physical activity behavior change (BC) for life-long secondary prevention. There is limited knowledge about factors influencing long-term physical ... -
Repeat traumatic brain injury exacerbates acute thalamic hyperconnectivity in humans
(Peer reviewed; Journal article, 2024)Repeated mild traumatic brain injury is of growing interest regarding public and sporting safety and is thought to have greater adverse or cumulative neurological effects when compared with single injury. While epidemiological ... -
Clinical and Imaging Characteristics, Care Pathways, and Outcomes of Traumatic Epidural Hematomas: A Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury Study
(Peer reviewed; Journal article, 2024)BACKGROUND AND OBJECTIVES: Guideline recommendations for surgical management of traumatic epidural hematomas (EDHs) do not directly address EDHs that co-occur with other intracranial hematomas; the relative rates of isolated ... -
Early versus delayed cranioplasty after decompressive craniectomy in traumatic brain injury: a multicenter observational study within CENTER-TBI and Net-QuRe
(Peer reviewed; Journal article, 2024)OBJECTIVE The aim of this study was to compare the outcomes of early (≤ 90 days) and delayed (> 90 days) cranioplasty following decompressive craniectomy (DC) in patients with traumatic brain injury (TBI). METHODS The ...