Browsing Institutt for nevromedisin og bevegelsesvitenskap by Journals "Scientific Reports"
Now showing items 1-20 of 20
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A prospective three-year follow-up study on the clinical significance of anti-neuronal antibodies in acute psychiatric disorders
(Peer reviewed; Journal article, 2019)The clinical significance of anti-neuronal antibodies for psychiatric disorders is controversial. We investigated if a positive anti-neuronal antibody status at admission to acute psychiatric inpatient care was associated ... -
Acute effects of high intensity training on cardiac function: a pilot study comparing subjects with type 2 diabetes to healthy controls
(Peer reviewed; Journal article, 2022)This study evaluated acute cardiac stress after a high-intensity interval training session in patients with type 2 diabetes (T2D) versus healthy controls. High intensity aerobic exercise was performed by 4 × 4-min intervals ... -
Assessing mechanisms of frequency discrimination by comparison of different measures over a wide frequency range
(Peer reviewed; Journal article, 2023)It has been hypothesized that auditory detection of frequency modulation (FM) for low FM rates depends on the use of both temporal (phase locking) and place cues, depending on the carrier frequency, while detection of FM ... -
Cerebrospinal fluid sTREM2 in Alzheimer’s disease: comparisons between clinical presentation and AT classification
(Peer reviewed; Journal article, 2020)Triggering receptor expressed on myeloid cells 2 (TREM2) is an innate immune receptor expressed by microglia. Its cleaved fragments, soluble TREM2 (sTREM2), can be measured in the cerebrospinal fluid (CSF). Previous studies ... -
EEG-derived brain graphs are reliable measures for exploring exercise-induced changes in brain networks
(Peer reviewed; Journal article, 2021)The interaction of acute exercise and the central nervous system evokes increasing interest in interdisciplinary research fields of neuroscience. Novel approaches allow to monitor large-scale brain networks from mobile ... -
Evening light environments can be designed to consolidate and increase the duration of REM-sleep
(Peer reviewed; Journal article, 2022)Evening exposure to short-wavelength light has disruptive effects on circadian rhythms and sleep. These effects can be mitigated by blocking short-wavelength (blue) frequencies, which has led to the development of evening ... -
Functional metabolic interactions of human neuron-astrocyte 3D in vitro networks
(Peer reviewed; Journal article, 2016)The generation of human neural tissue-like 3D structures holds great promise for disease modeling, drug discovery and regenerative medicine strategies. Promoting the establishment of complex cell-cell interactions, 3D ... -
GBA and APOE ε4 associate with sporadic dementia with Lewy bodies in European genome wide association study
(Journal article; Peer reviewed, 2019)Dementia with Lewy Bodies (DLB) is a common neurodegenerative disorder with poor prognosis and mainly unknown pathophysiology. Heritability estimates exceed 30% but few genetic risk variants have been identified. Here we ... -
Genetic risk score associations for myocardial infarction are comparable in persons with and without rheumatoid arthritis: the population-based HUNT study
(Peer reviewed; Journal article, 2020)Persons with rheumatoid arthritis (RA) have increased risk of myocardial infarction (MI). Overlapping associations with MI of weighted genetic risk scores (wGRS) for coronary artery disease (CAD) and RA is unknown in a ... -
Inflammation mediates approximately one quarter of excess relative all-cause mortality in persons with rheumatoid arthritis: the Trøndelag Health Study
(Peer reviewed; Journal article, 2022)Inflammation may contribute to excess mortality in rheumatoid arthritis (RA) patients. We investigated associations to all-cause mortality of the inflammation markers high-sensitivity C-reactive protein (CRP), lactoferrin ... -
Long-term drug effectiveness and survival for reference rituximab in rheumatoid arthritis patients in an ordinary outpatient clinic
(Peer reviewed; Journal article, 2022)To explore the long-term drug effectiveness and survival of reference rituximab (ref-RTX)-treated rheumatoid arthritis (RA) patients in an ordinary outpatient clinic. Second, we explored baseline predictors of drug ... -
Measurement invariance of six language versions of the post-traumatic stress disorder checklist for DSM-5 in civilians after traumatic brain injury
(Peer reviewed; Journal article, 2022)Traumatic brain injury (TBI) is frequently associated with neuropsychiatric impairments such as symptoms of post-traumatic stress disorder (PTSD), which can be screened using self-report instruments such as the Post-Traumatic ... -
Meta-analysis of Alzheimer’s disease on 9,751 samples from Norway and IGAP study identifies four risk loci
(Journal article; Peer reviewed, 2018)A large fraction of genetic risk factors for Alzheimer’s Disease (AD) is still not identified, limiting the understanding of AD pathology and study of therapeutic targets. We conducted a genome-wide association study (GWAS) ... -
A nationwide study of patients operated for cervical degenerative disorders in public and private hospitals
(Peer reviewed; Journal article, 2022)During the last decades, there has been an increase in the rate of surgery for degenerative disorders of the cervical spine and in the use of supplementary private health insurance. Still, there is limited knowledge about ... -
Raidionics: an open software for pre- and postoperative central nervous system tumor segmentation and standardized reporting
(Peer reviewed; Journal article, 2023)For patients suffering from central nervous system tumors, prognosis estimation, treatment decisions, and postoperative assessments are made from the analysis of a set of magnetic resonance (MR) scans. Currently, the lack ... -
Segmentation of glioblastomas in early post-operative multi-modal MRI with deep neural networks
(Peer reviewed; Journal article, 2023)Extent of resection after surgery is one of the main prognostic factors for patients diagnosed with glioblastoma. To achieve this, accurate segmentation and classification of residual tumor from post-operative MR images ... -
Smoking is associated with impaired verbal learning and memory performance in women more than men
(Peer reviewed; Journal article, 2021)Vascular contributions to cognitive impairment and dementia (VCID) include structural and functional blood vessel injuries linked to poor neurocognitive outcomes. Smoking might indirectly increase the likelihood of cognitive ... -
The Direction of Tumour Growth in Glioblastoma Patients
(Journal article; Peer reviewed, 2018)Generating MR-derived growth pattern models for glioblastoma multiforme (GBM) has been an attractive approach in neuro-oncology, suggesting a distinct pattern of lesion spread with a tendency in growing along the white ... -
Trajectories of brain development in school-age children born preterm with very low birth weight
(Journal article; Peer reviewed, 2018)Preterm birth (gestational age < 37 weeks) with very low birth weight (VLBW, birth weight ≤ 1500 g) is associated with lifelong cognitive deficits, including in executive function, and persistent alterations in cortical ... -
Within-session verbal learning slope is predictive of lifespan delayed recall, hippocampal volume, and memory training benefit, and is heritable
(Journal article; Peer reviewed, 2020)Memory performance results from plasticity, the ability to change with experience. We show that benefit from practice over a few trials, learning slope, is predictive of long-term recall and hippocampal volume across a ...