Blar i Institutt for nevromedisin og bevegelsesvitenskap på tidsskrift "Frontiers in Neurology"

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    • A European perspective on auditory processing disorder-current knowledge and future research focus 

      Iliadou, Vasiliki; Ptok, Martin; Grech, Helen; Pedersen, Ellen Raben; Brechmann, Andre; Deggouj, Naima; Kiese-Himmel, Christiane; Sliwinska-Kowalska, Mariola; Nickisch, Andreas; Demanez, Laurent; Veuillet, Evelyne; Thai-Van, Hung; Sirimanna, Tony; Callimachou, Marina; Santarelli, Rosamaria; Kuske, Sandra; Barajas, Jose; Hedjever, Mladen; Konukseven, Ozlem; Veraguth, Dorothy; Mattsson, Tone Stokkereit; Martins, Jorge Humberto; Bamiou, Doris-Eva (Journal article; Peer reviewed, 2017)
      Current notions of “hearing impairment,” as reflected in clinical audiological practice, do not acknowledge the needs of individuals who have normal hearing pure tone sensitivity but who experience auditory processing ...

    • Clinical and Imaging Markers of Prodromal Parkinson's Disease 

      Hustad, Eldbjørg; Aasly, Jan (Peer reviewed; Journal article, 2020)
      The diagnosis of Parkinson's disease (PD) relies on the clinical effects of dopamine deficiency, including bradykinesia, rigidity and tremor, usually manifesting asymmetrically. Misdiagnosis is common, due to overlap of ...

    • Developing Cognition Endpoints for the CENTER-TBI Neuropsychological Test Battery 

      Stenberg, Jonas; Karr, Justin E.; Terry, Douglas P.; Saksvik, Simen Berg; Vik, Anne; Skandsen, Toril; Silverberg, Noah D.; Iverson, Grant L. (Peer reviewed; Journal article, 2020)
      Background: Measuring cognitive functioning is common in traumatic brain injury (TBI) research, but no universally accepted method for combining several neuropsychological test scores into composite, or summary, scores ...

    • Ecological validity of a deep learning algorithm to detect gait events from real-life walking bouts in mobility-limiting diseases 

      Romijnders, Robbin; Salis, Francesca; Hansen, Clint; Küderle, Arne; Paraschiv-Ionescu, Anisoara; Cereatti, Andrea; Alcock, Lisa; Aminian, Kamiar; Becker, Clemens; Bertuletti, Stefano; Bonci, Tecla; Brown, Philip; Buckley, Ellen; Cantu, Alma; Carsin, Anne-Elie; Caruso, Marco; Caulfield, Brian; Chiari, Lorenzo; D'Ascanio, Ilaria; Del Din, Silvia; Eskofier, Björn; Fernstad, Sara Johansson; Fröhlich, Marceli Stanislaw; Garcia Aymerich, Judith; Gazit, Eran; Hausdorff, Jeffrey M.; Hiden, Hugo; Hume, Emily; Keogh, Alison; Kirk, Cameron; Kluge, Felix; Koch, Sarah; Mazzà, Claudia; Megaritis, Dimitrios; Micó-Amigo, Encarna; Müller, Arne; Palmerini, Luca; Rochester, Lynn; Schwickert, Lars; Scott, Kirsty; Sharrack, Basil; Singleton, David; Soltani, Abolfazl; Ullrich, Martin; Vereijken, Beatrix; Vogiatzis, Ioannis; Yarnall, Alison; Schmidt, Gerhard; Maetzler, Walter (Peer reviewed; Journal article, 2023)
      Introduction: The clinical assessment of mobility, and walking specifically, is still mainly based on functional tests that lack ecological validity. Thanks to inertial measurement units (IMUs), gait analysis is shifting ...

    • The Effect of Increased Gait Speed on Asymmetry and Variability in Children With Cerebral Palsy 

      Brændvik, Siri Merete; Goihl, Tobias; Braaten, Ragnhild Sunde; Vereijken, Beatrix (Journal article; Peer reviewed, 2020)
      Gait of children and adolescents with cerebral palsy (CP) is often reported to be more asymmetric and variable than gait of typically developing (TD) peers. As this may lead to less stable and less efficient gait, a relevant ...

    • Examining Test-Retest Reliability and Reliable Change for Cognition Endpoints for the CENTER-TBI Neuropsychological Test Battery 

      Stenberg, Jonas; Karr, Justin E.; Karlsen, Rune Hatlestad; Skandsen, Toril; Silverberg, Noah D.; Iverson, Grant L. (Peer reviewed; Journal article, 2020)
      Objective: Seven candidate cognition composite scores have been developed and evaluated as part of a research program designed to validate a cognition endpoint for traumatic brain injury (TBI) research and clinical trials, ...

    • The Human Brain Representation of Odor Identification in Amnestic Mild Cognitive Impairment and Alzheimer's Dementia of Mild Degree 

      Kjelvik, Grete; Evensmoen, Hallvard Røe; Hummel, Thomas; Engedal, Knut; Selbæk, Geir; Saltvedt, Ingvild; Håberg, Asta (Peer reviewed; Journal article, 2020)
      Background: Odor identification (OI) ability is a suggested early biomarker of Alzheimer’s disease. In this study, we investigated brain activity within the brain’s olfactory network associated with OI in patients with ...

    • The Impact of Vascular Risk Factors on Post-stroke Cognitive Impairment: The Nor-COAST Study 

      Aam, Stina; Gynnild, Mari Nordbø; Munthe-Kaas, Ragnhild; Saltvedt, Ingvild; Lydersen, Stian; Knapskog, Anne Brita; Ihle-Hansen, Hege; Ellekjær, Hanne; Eldholm, Rannveig Sakshaug; Fure, Brynjar (Peer reviewed; Journal article, 2021)
      Introduction: Post-stroke cognitive impairment (PSCI) is common, but evidence on the impact of vascular risk factors is lacking. We explored the association between pre-stroke vascular risk factors and PSCI and studied the ...

    • Incidence of mild traumatic brain injury: A prospective hospital, emergency room and general practitioner-based study 

      Skandsen, Toril; Nilsen, Tom Ivar Lund; Einarsen, Cathrine Elisabeth; Normann, Ingunn; McDonagh, David; Håberg, Asta; Vik, Anne (Peer reviewed; Journal article, 2019)
      Background: There are no recent estimates of incidence rates of mild traumatic brain injury (MTBI) from Norway. Moreover, reported incidence rates rarely comprise cases of MTBI evaluated in the primary care setting. In ...

    • Injury Causes and Severity in Pediatric Traumatic Brain Injury Patients Admitted to the Ward or Intensive Care Unit: A Collaborative European Neurotrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) Study 

      Riemann, Lennart; Zweckberger, Klaus; Unterberg, Andreas; El Damaty, , Ahmed; Younsi, Alexander; Andelic, Nada; Andreassen, Lasse; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Skandsen, Toril; Vik, Anne (Journal article; Peer reviewed, 2020)
      Background: Traumatic brain injury (TBI) is the leading cause of death and disability in children. It includes a range of different pathologies that differ considerably from adult TBI. Analyzing and understanding injury ...

    • Longitudinal Brain Changes After Stroke and the Association With Cognitive Decline 

      Aamodt, Eva Birgitte; Lydersen, Stian; Alnæs, Dag; SCHELLHORN, TILL; Saltvedt, Ingvild; Beyer, Mona K.; Håberg, Asta (Peer reviewed; Journal article, 2022)
      Background: Cognitive impairment is common after stroke. So is cortical- and subcortical atrophy, with studies reporting more atrophy in the ipsilesional hemisphere than the contralesional hemisphere. The current study ...

    • Longitudinal Monitoring of Parkinson's Disease in Different Ethnic Cohorts: The DodoNA and LONG-PD Study 

      Markopoulou, Katerina; Aasly, Jan; Ju Chung, Sun; Dardiotis, Efthimios; Wirdefeldt, Karin; Premkumar, Ashvini; Schoneburg, Bernadette; Kartha, Ninith; Wilk, Gary; Wei, Jun Rong; Simon, Kelly Claire; Tideman, Samuel; Epshteyn, Alexander; Hadsell, Bryce; Garduno, Lisette; Pham, Anna; Frigerio, Roberta; Maraganore, Demetrius M. (Peer reviewed; Journal article, 2020)
      Background: Different factors influence severity, progression, and outcomes in Parkinson's disease (PD). Lack of standardized clinical assessment limits comparison of outcomes and availability of well-characterized cohorts ...

    • Mitochondrial Mechanisms of LRRK2 G2019S Penetrance 

      Delcambre, Sylvie; Ghelfi, Jenny; Ouzren, Nazzima; Grandmougin, Lea; Delbrouck, Catherine; Seibler, Philip; Wasner, Kobi; Aasly, Jan; Klein, Christine; Trinh, Joanne; Pereira, Sandro L; Grünewald, Anne (Peer reviewed; Journal article, 2020)
      Several mutations in leucine-rich repeat kinase-2 (LRRK2) have been associated with Parkinson's disease (PD). The most common substitution, G2019S, interferes with LRRK2 kinase activity, which is regulated by autophosphorylation. ...

    • Neurodegenerative interplay of cardiovascular autonomic dysregulation and the retina in early multiple sclerosis 

      Benavent, Sigrid Aune de Rodez; Nygaard, Gro Owren; Nilsen, Kristian Bernhard; Etholm, Lars; Sowa, Piotr; Gustavsen, Marte Wendel; Harbo, Hanne Flinstad; Drolsum, Liv; Laeng, Bruno; Kerty, Emilia; Celius, Elisabeth Gulowsen (Journal article; Peer reviewed, 2019)
      Introduction: Autonomic nervous system (ANS) symptoms are prevalent in multiple sclerosis (MS) as is neurodegeneration. Our aim was to explore the occurrence of ANS symptoms and retinal neurodegeneration in a newly diagnosed ...

    • One-Year Prospective Study of Plasma Biomarkers From CNS in Patients With Mild Traumatic Brain Injury 

      Clarke, Gerard Janez Brett; Clarke, Gerard; Skandsen, Toril; Zetterberg, Henrik; Einarsen, Cathrine Elisabeth; Feyling, Casper Kongstein; Follestad, Turid; Vik, Anne; Blennow, Kaj; Håberg, Asta (Peer reviewed; Journal article, 2021)
      Objective: To investigate the longitudinal evolution of three blood biomarkers: neurofilament light (NFL), glial fibrillary acidic protein (GFAP) and tau, in out-patients and hospitalized patients with mild traumatic brain ...

    • An open-label observational study and meta-analysis of non-invasive vagus nerve stimulation in medically refractory chronic cluster headache 

      Simmonds, Lucy; Lagrata, Susie; Stubberud, Anker; Cheema, Sanjay; Tronvik, Erling Andreas; Matharu, Manjit; Kamourieh, Salwa (Peer reviewed; Journal article, 2023)
      Background: Many patients with cluster headache (CH) are inadequately controlled by current treatment options. Non-invasive vagus nerve stimulation (nVNS) is reported to be effective in the management of CH though some ...

    • Post-stroke Cognitive Impairment—Impact of Follow-Up Time and Stroke Subtype on Severity and Cognitive Profile: The Nor-COAST Study 

      Aam, Stina; Einstad, Marte Stine; Munthe-Kaas, Ragnhild; Lydersen, Stian; Ihle-Hansen, Hege; Knapskog, Anne Brita; Ellekjær, Hanne; Seljeseth, Yngve Müller; Saltvedt, Ingvild (Peer reviewed; Journal article, 2020)
      Background: Post-stroke cognitive impairment (PSCI) is common, but evidence of cognitive symptom profiles, course over time, and pathogenesis is scarce. We investigated the significance of time and etiologic stroke subtype ...

    • Preoperative Brain Tumor Imaging: Models and Software for Segmentation and Standardized Reporting 

      Bouget, David Nicolas Jean-Mar; Pedersen, André; Jakola, Asgeir S.; Kavouridis, Vasileios; Emblem, Kyrre Eeg; Eijgelaar, Roelant S; Kommers, Ivar; Ardon, Hilko; Barkhof, Frederik; Bello, Lorenzo; Berger, Mitchel S.; Nibali, Marco Conti; Furtner, Julia; Hervey-Jumper, Shawn; Idema, Albert J. S.; Kiesel, Barbara; Kloet, Alfred; Mandonnet, Emmanuel; Müller, Domenique M. J.; Robe, Pierre A; Rossi, Marco; Sciortino, Tommaso; van den Brink, Wimar A.; Wagemakers, Michiel; Widhalm, Georg; Witte, Marnix G.; Zwinderman, Aeilko H.; Hamer, Philip C De Witt; Solheim, Ole; Reinertsen, Ingerid (Peer reviewed; Journal article, 2022)
      For patients suffering from brain tumor, prognosis estimation and treatment decisions are made by a multidisciplinary team based on a set of preoperative MR scans. Currently, the lack of standardized and automatic methods ...

    • Resilience and Its Association With Activities of Daily Living 3 Months After Stroke 

      Norvang, Ole Petter; Dahl, Anne Eitrem; Thingstad, Pernille; Askim, Torunn (Peer reviewed; Journal article, 2022)
      Independence in basic activities of daily living (ADL) is an important outcome after stroke. Identifying factors associated with independence can contribute to improve post-stroke rehabilitation. Resilience, which is the ...

    • Self-reported cognitive and psychiatric symptoms at 3 months predict single-item measures of fatigue and daytime sleep 12 months after ischemic stroke 

      Kliem, Elisabeth; Labberton, Angela Susan; Barra, Mathias; Olsen, Alexander; Thommessen, Bente; Thomas, Owen Matthew Truscott; Gjestad, Elise Ødegård; Indredavik, Bent; Grambaite, Ramune (Peer reviewed; Journal article, 2022)
      Introduction: Post-stroke fatigue and increased need for daytime sleep are multidimensional and insufficiently understood sequelae. Our aim was to study the relationships of self-reported cognitive and psychiatric symptoms ...