• Bidirectionality of antiseizure and antipsychotic treatment: A population-based study 

      Revdal, Eline; Morken, Gunnar; Bakken, Inger Johanne; Bråthen, Geir; Landmark, Cecilie Johannessen; Brodtkorb, Eylert (Peer reviewed; Journal article, 2022)
      Purpose To study the prevalence and directionality of comorbid epilepsy and psychosis in Norway. Methods The Norwegian Prescription Database (NorPD) provided individual-based information on all antiseizure medications ...
    • Clinical experience combined with therapeutic drug monitoring of lacosamide 

      Svendsen, Torleiv; Brodtkorb, Eylert; Baftiu, Arton; Lossius, Morten; Nakken, Karl Otto; Johannessen, Svein Ivar; Landmark, Cecilie Johannessen (Peer reviewed; Journal article, 2019)
      Objective Lacosamide (LCM) is an antiepileptic drug (AED) with insufficient clinical experience in patients with intellectual disability (ID). They often have more severe epilepsy with comorbidities. The objective was to ...
    • Efficacy, tolerability and pharmacokinetic variability of brivaracetam in adults with difficult-to-treat epilepsy 

      Svendsen, Torleiv; Brodtkorb, Eylert; Linge, Hanna Lande; Burns, Margrete Larsen; Johannessen, Svein Ivar; Nakken, Karl Otto; Lossius, Morten Ingvar; Landmark, Cecilie Johannessen (Peer reviewed; Journal article, 2022)
      Purpose: Brivaracetam (BRV) is one of our latest antiseizure medications (ASMs). It is an analogue of levetiracetam with limited real-life experience. The purpose of this study was to evaluate clinical experience with BRV ...
    • Pharmacokinetic data on brivaracetam, lacosamide and Perampanel during pregnancy and lactation 

      Landmark, Cecilie Johannessen; Rektorlie, Lene; Burns, Margrete Larsen; Revdal, Eline; Johannessen, Svein Ivar; Brodtkorb, Eylert (Peer reviewed; Journal article, 2021)
      We present pharmacokinetic data during pregnancy and lactation for brivaracetam, lacosamide and perampanel based on two case studies. Patient 1 used brivaracetam as monotherapy and gave birth to twins. Patient 2 used a ...
    • Reference ranges for antiepileptic drugs revisited: a practical approach to establish national guidelines 

      Reimers, Arne; Berg, Jon Andsnes; Burns, Margrete Larsen; Brodtkorb, Eylert; Johannessen, Svein Ivar; Landmark, Cecilie Johannessen (Journal article; Peer reviewed, 2018)
      Background and objective: Laboratories sometimes use different reference ranges for the same antiepileptic drug (AED), particularly for new and poorly investigated drugs. This may contribute to misunderstandings, concerns ...
    • The Impact of Pharmacokinetic Interactions with Eslicarbazepine Acetate Versus Oxcarbazepine and Carbamazepine in Clinical Practice 

      Landmark, Cecilie Johannessen; Svendsen, Torleiv; Dinarevic, Jasmin; Kufaas, Ruben F.; Reimers, Arne; Brodtkorb, Eylert; Baftiu, Arton; Burns, Margrete Larsen; Johannessen, Svein Ivar (Journal article; Peer reviewed, 2016)
      Background: Eslicarbazepine acetate (ESL) is a new anti-epileptic drug (AED) chemically related to oxcarbazepine (OXC) and carbamazepine (CBZ) and is increasingly used in clinical practice. The purpose of the study was to ...
    • Therapeutic Drug Monitoring of Lacosamide in Norway: Focus on Pharmacokinetic Variability, Efficacy and Tolerability. 

      Svendsen, Torleiv; Brodtkorb, Eylert; Baftiu, Arton; Burns, Margrete Larsen; Johannessen, Svein Ivar; Landmark, Cecilie Johannessen (Journal article; Peer reviewed, 2017)
      Lacosamide (LCM) is a new antiepileptic drug (AED). Experience from therapeutic drug monitoring (TDM) in clinical practice is limited. The purpose of this study is to evaluate the pharmacokinetic variability of LCM in ...