• Are there predilection sites for intracranial meningioma? A population-based atlas 

      Hosainey, Sayied Abdol Mohieb; Bouget, David; Reinertsen, Ingerid; Sagberg, Lisa Millgård; Torp, Sverre Helge; Jakola, Asgeir Store; Solheim, Ole (Peer reviewed; Journal article, 2021)
      Meningioma is the most common benign intracranial tumor and is believed to arise from arachnoid cap cells of arachnoid granulations. We sought to develop a population-based atlas from pre-treatment MRIs to explore the ...
    • Brain atlas for assessing the impact of tumor location on perioperative quality of life in patients with high-grade glioma: A prospective population-based cohort study 

      Sagberg, Lisa Millgård; Iversen, Daniel Høyer; Fyllingen, Even Hovig; Jakola, Asgeir Store; Reinertsen, Ingerid; Solheim, Ole (Journal article; Peer reviewed, 2019)
      Background Tumor location is important for surgical decision making. Particular attention is paid to regions that contain sensorimotor and language functions, but it is unknown if these are the most important regions from ...
    • Comparative effectiveness of microdecompression and laminectomy for central lumbar spinal stenosis: Study protocol for an observational study 

      Nerland, Ulf Skule; Jakola, Asgeir Store; Solheim, Ole; Weber, Clemens; Rao, Vidar; Lønne, Greger; Solberg, Tore; Salvesen, Øyvind; Carlsen, Sven Magnus; Nygaard, Øystein Petter; Gulati, Sasha (Journal article; Peer reviewed, 2014)
      Introduction: This observational study is designed to test the equivalence between the clinical effectiveness of microdecompression and laminectomy in the surgical treatment of central lumbar spinal stenosis. Lumbar spinal ...
    • Depression and ability to work after vestibular schwannoma surgery: a nationwide registry-based matched cohort study on antidepressants, sedatives, and sick leave 

      Thurin, Erik; Förander, Petter; bartek, Jiri Jr.; Gulati, Sasha; Rydén, Isabelle; Smits, Anja; Hesselager, Göran; Salvesen, Øyvind; Jakola, Asgeir Store (Peer reviewed; Journal article, 2021)
      Background In patients with vestibular schwannomas (VS), tumor control is often achieved, and life expectancy is relatively good. The main risks of surgical treatment are hearing loss and facial nerve function. The occurrence ...
    • Does risk of brain cancer increase with intracranial volume? A population-based case control study 

      Fyllingen, Even Hovig; Hansen, Tor Ivar; Jakola, Asgeir Store; Håberg, Asta; Salvesen, Øyvind; Solheim, Ole (Journal article; Peer reviewed, 2018)
      Background Glioma is the most common primary brain tumor and is believed to arise from glial stem cells. Despite large efforts, there are limited established risk factors. It has been suggested that tissue with more ...
    • Effect of Disulfiram and Copper Plus Chemotherapy vs Chemotherapy Alone on Survival in Patients with Recurrent Glioblastoma: A Randomized Clinical Trial 

      Werlenius, Katja; Kinhult, Sara; Solheim, Tora S; Magelssen, Henriette; Löfgren, David; Mudaisi, Munila; Hylin, Sofia; Bartek, Jiri; Strandéus, Michael; Lindskog, Magnus; Rashid, Havyan Bahroz; Carstam, Louise; Gulati, Sasha; Solheim, Ole Skeidsvoll; Salvesen, Øyvind Olav; Jakola, Asgeir Store (Peer reviewed; Journal article, 2023)
      Importance Disulfiram has demonstrated broad antitumoral effect in several preclinical studies. One of the proposed indications is for the treatment of glioblastoma. Objective To evaluate the efficacy and safety of ...
    • Effect of Spinal Cord Burst Stimulation vs Placebo Stimulation on Disability in Patients With Chronic Radicular Pain After Lumbar Spine Surgery: A Randomized Clinical Trial 

      Hara, Sozaburo; Andresen, Hege; Solheim, Ole; Carlsen, Sven Magnus; Sundstrøm, Terje; Lønne, Greger; Vangen-Lønne, Vetle; Taraldsen, Kristin; Tronvik, Erling Andreas; Øie, Lise Rystad; Gulati, Agnete Malm; Sagberg, Lisa Millgård; Jakola, Asgeir Store; Solberg, Tore; Nygaard, Øystein Petter; Salvesen, Øyvind; Gulati, Sasha (Peer reviewed; Journal article, 2022)
      Importance: The use of spinal cord stimulation for chronic pain after lumbar spine surgery is increasing, yet rigorous evidence of its efficacy is lacking. Objective: To investigate the efficacy of spinal cord burst ...
    • Functional outcome and survival following spontaneous intracerebral hemorrhage: A retrospective population-based study 

      Øie, Lise Rystad; Madsbu, Mattis Aleksander; Solheim, Ole; Jakola, Asgeir Store; Giannadakis, Charalampis; Vorhaug, Anders; Padayachy, Llewellyn; Jensberg, Heidi; Dodick, David W.; Salvesen, Øyvind; Gulati, Sasha (Journal article; Peer reviewed, 2018)
      Background Accurate and reliable clinical and radiological predictors of intracerebral hemorrhage (ICH) outcomes are needed to optimize treatment of ICH. The aim of this study was to investigate functional outcome and ...
    • Impact of meningioma surgery on use of antiepileptic, antidepressant, and sedative drugs: A Swedish nationwide matched cohort study 

      Thurin, Erik; Rydén, Isabelle; Skoglund, Thomas; Smits, Anja; Gulati, Sasha; Hesselager, Göran; Bartek, Jiri Jr.; Henriksson, Roger; Salvesen, Øyvind; Jakola, Asgeir Store (Peer reviewed; Journal article, 2021)
      Background: Meningioma is the most common primary intracranial tumor and surgery is the main treatment modality. As death from lack of tumor control is rare, other outcome measures like anxiety, depression and post-operative ...
    • Is intracranial volume a risk factor for IDH-mutant low-grade glioma? A case-control study 

      Sagberg, Lisa Millgård; Fyllingen, Even Hovig; Hansen, Tor Ivar; Strand, Per Sveino; Håvik, Aril Løge; Sundstrøm, Terje; Corell, Alba; Jakola, Asgeir Store; Salvesen, Øyvind; Solheim, Ole (Peer reviewed; Journal article, 2022)
      Purpose Risk of cancer has been associated with body or organ size in several studies. We sought to investigate the relationship between intracranial volume (ICV) (as a proxy for lifetime maximum brain size) and risk of ...
    • Long-term follow up of patients with WHO grade 2 oligodendroglioma 

      Carstam, Louise; Latini, Francesco; Solheim, Ole Skeidsvoll; Bartek, Jiri; Pedersen, Lars Kjelsberg; Zetterling, Maria; Beniaminov, Stanislav; Sjåvik, Kristin; Ryttlefors, Mats; Jensdottir, Margret; Rydenhag, Bertil; Smits, Anja; Jakola, Asgeir Store (Peer reviewed; Journal article, 2023)
      Purpose Since the introduction of the molecular definition of oligodendrogliomas based on isocitrate dehydrogenase (IDH)-status and the 1p19q-codeletion, it has become increasingly evident how this glioma entity differs ...
    • Neurosurgical treatment and outcome patterns of meningioma in Sweden: a nationwide registry-based study 

      Corell, Alba; Thurin, Erik; Skoglund, Thomas; Farahmand, Dan; Henriksson, Roger; Rydenhag, Bertil; Gulati, Sasha; Bártek, Jiří; Jakola, Asgeir Store (Peer reviewed; Journal article, 2019)
      Background Surgery is the main treatment modality for intracranial meningiomas, but data on short-term surgical outcome are limited. The aim of this Swedish nationwide registry-based study was to benchmark the 30-day ...
    • Psychotropic and anti-epileptic drug use, before and after surgery, among patients with low-grade glioma: a nationwide matched cohort study 

      Rydén, Isabelle; Thurin, Erik; Carstam, Louise; Smits, Anja; Gulati, Sasha; Henriksson, Roger; Salvesen, Øyvind; Jakola, Asgeir Store (Journal article; Peer reviewed, 2021)
      Background: Low-grade glioma (LGG) is a relatively rare type of brain tumour. The use of antidepressant, sedative and anti-epileptic drugs can reflect the burden of the disease. While epilepsy is well-described in patients ...
    • Quantitative texture analysis in the prediction of IDH status in low-grade gliomas 

      Jakola, Asgeir Store; Zang, YH; Skjulsvik, Anne Jarstein; Solheim, Ole; Bø, Hans Kristian; Berntsen, Erik Magnus; Reinertsen, Ingerid; Gulati, Sasha; Förander, Petter; Brismar, Torkel B. (Journal article; Peer reviewed, 2017)
      Objectives Molecular markers provide valuable information about treatment response and prognosis in patients with low-grade gliomas (LGG). In order to make this important information available prior to surgery the aim of ...
    • Return to work following meningioma surgery: a Swedish nationwide registry-based matched cohort study 

      Thurin, Erik; Corell, Alba; Gulati, Sasha; Smits, Anja; Henriksson, Roger; Bartek, Jiri Jr.; Salvesen, Øyvind; Jakola, Asgeir Store (Peer reviewed; Journal article, 2020)
      Background Meningioma is the most common primary intracranial tumor. It is usually slow growing and benign, and surgery is the main treatment modality. There are limited data on return to work following meningioma ...
    • Risk of intracranial hemorrhage (RICH) in users of oral antithrombotic drugs: Nationwide pharmacoepidemiological study 

      Gulati, Sasha; Solheim, Ole; Carlsen, Sven Magnus; Øie, Lise Rystad; Jensberg, Heidi; Gulati, Agnete Malm; Madsbu, Mattis Aleksander; Giannadakis, Charalampis; Jakola, Asgeir Store; Salvesen, Øyvind (Journal article; Peer reviewed, 2018)
      Background The risks of intracranial haemorrhage (ICH) associated with antithrombotic drugs outside clinical trials are gaining increased attention. The aim of this nationwide study was to investigate the risk of ICH ...
    • Risks and benefits of brain tumor surgery: A balancing act 

      Jakola, Asgeir Store (Doktoravhandlinger ved NTNU, 1503-8181; 2013:158, Doctoral thesis, 2013)
    • Segmentation of glioblastomas in early post-operative multi-modal MRI with deep neural networks 

      Helland, Ragnhild Holden; Ferles, Alexandros; Pedersen, Andre; Kommers, Ivar; Ardon, Hilko; Barkhof, Frederik; Bello, Lorenzo; Berger, Mitchel S.; Dunås, Tora; Nibali, Marco Conti; Furtner, Julia; Hervey-Jumper, Shawn; Idema, Albert J. S.; Kiesel, Barbara; Tewari, Rishi Nandoe; Mandonnet, Emmanuel; Müller, Domenique M. J.; Robe, Pierre A.; Rossi, Marco; Sagberg, Lisa Millgård; Sciortino, Tommaso; Aalders, Tom; Wagemakers, Michiel; Widhalm, Georg; Witte, Marnix G.; Zwinderman, Aeilko H.; Majewska, Paulina Luiza; Jakola, Asgeir Store; Solheim, Ole Skeidsvoll; Hamer, Philip C. De Witt; Reinertsen, Ingerid; Eijgelaar, Roelant S.; Bouget, David Nicolas Jean-Marie (Peer reviewed; Journal article, 2023)
      Extent of resection after surgery is one of the main prognostic factors for patients diagnosed with glioblastoma. To achieve this, accurate segmentation and classification of residual tumor from post-operative MR images ...
    • Stemness and clinical features in relation to the subventricular zone in diffuse lower-grade glioma: An exploratory study 

      Corell, Alba; Gómez Vecchio, Tomás; Ferreyra Vega, Sandra; Dénes, Anna; Neimantaite, Alice; Hagerius, Alexander; Barchéus, Hanna; Solheim, Ole; Lindskog, Cecilia; Bontell, Thomas Olsson; Carén, Helena; Jakola, Asgeir Store; Smits, Anja (Peer reviewed; Journal article, 2022)
      Background The subventricular zone (SVZ) of the human brain is a site of adult stem cell proliferation and a microenvironment for neural stem cells (NSCs). It has been suggested that NSCs in the SVZ are potential cells ...
    • Survival of glioblastoma in relation to tumor location: a statistical tumor atlas of a population-based cohort 

      Fyllingen, Even Hovig; Bø, Lars Eirik; Reinertsen, Ingerid; Jakola, Asgeir Store; Sagberg, Lisa Millgård; Berntsen, Erik Magnus; Salvesen, Øyvind; Solheim, Ole (Peer reviewed; Journal article, 2021)
      Purpose Previous studies on the effect of tumor location on overall survival in glioblastoma have found conflicting results. Based on statistical maps, we sought to explore the effect of tumor location on overall survival ...