• Desflurane consumption with automated vapour control systems in two different anaesthesia machines. A randomized controlled study 

      Mostad, Dagmar; Klepstad, Pål; Follestad, Turid; Pleym, Hilde (Peer reviewed; Journal article, 2021)
      Background: In general anaesthesia practice a fresh gas flow (FGF) of ≥0.5 L/min is usually applied. Automated gas delivery devices are developed to reduce volatile anaesthetic consumption by limiting gas flow. This study ...
    • Effects of Adrenaline on maternal and fetal fentanyl absorption in epidural analgesia: a randomized trial 

      Haidl, Frans Felxi; Rosseland, Leiv Arne; Spigset, Olav; Dahl, Vegard (Journal article; Peer reviewed, 2018)
      Background The combination of low‐dose local anesthesia and lipophilic opioids such as fentanyl is established as a standard solution for labor epidural analgesia. Fentanyl increases efficacy, but may have negative effects ...
    • Open chest and pericardium facilitate transpulmonary passage of venous air emboli 

      Storm, Benjamin; Halvorsen, Per Steinar; Skulstad, Helge; Dybwik, Knut Gustav; Schjalm, Camilla; Christiansen, Dorte; Wisløff-Aase, Kristin; Fosse, Erik; Braaten, Tonje Bjørndal; Nielsen, Erik Waage; Mollnes, Tom Eirik (Peer reviewed; Journal article, 2021)
      Background Transpulmonary passage of air emboli can lead to fatal brain- and myocardial infarctions. We studied whether pigs with open chest and pericardium had a greater transpulmonary passage of venous air emboli than ...
    • A survey of anaesthesia practices at all hospitals performing caesarean sections in Sierra Leone 

      Lonnee, Herman; Taule, Katinka; Sandvand, Johannes Knoph; Koroma, Michael M.; Dumbuya, Abubakar; Jusu, Kakpama S.K.; Shour, Mohamed A.; van Duinen, Aalke Johan (Peer reviewed; Journal article, 2020)
      Background Providing safe anaesthesia is essential when performing caesarean sections, one of the most commonly performed types of surgery. Anaesthesia-related causes of maternal mortality are generally considered ...
    • The rare Arg181Cys mutation in the μ opioid receptor can abolish opioid responses 

      Skorpen, Frank; von Hofacker, Sebastian; Bjørngaard, Mads; Skogholt, Anne Heidi; Dale, Ola; Kaasa, Stein; Klepstad, Pål (Journal article; Peer reviewed, 2016)
      BACKGROUND: Genetic variability contributes to variable clinical response to opioids. This study emerged from the observation of three Norwegian patients who showed no or extraordinary poor response to very high doses of ...