Blar i Institutt for klinisk og molekylær medisin på forfatter "Xu, Shuang"
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Combinations of Host- and Virus-Targeting Antiviral Drugs Confer Synergistic Suppression of SARS-CoV-2
Wagoner, Jessica; Herring, Shawn; Hsiang, Tien-Ying; Ianevski, Aleksandr; Biering, Scott B.; Xu, Shuang; Hoffmann, Markus; Pöhlmann, Stefan; Gale, Michael; Aittokallio, Tero Antero; Schiffer, Joshua T.; White, Judith M.; Polyaka, Stephen J. (Peer reviewed; Journal article, 2022)Three directly acting antivirals (DAAs) demonstrated substantial reduction in COVID-19 hospitalizations and deaths in clinical trials. However, these agents did not completely prevent severe illness and are associated with ... -
Drug Combinations as a First Line of Defense against Coronaviruses and Other Emerging Viruses
White, Judith M.; Schiffer, Joshua T.; Bender Ignacio, Rachel A.; Xu, Shuang; Kainov, Denis; Ianevski, Aleksandr; Aittokallio, Tero Antero; Frieman, Matthew; Olinger, Gene G.; Polyak, Stephen J. (Journal article; Peer reviewed, 2021)The world was unprepared for coronavirus disease 2019 (COVID-19) and remains ill-equipped for future pandemics. While unprecedented strides have been made developing vaccines and treatments for COVID-19, there remains a ...