• A cross-sectional study examining the prevalence of cachexia and areas of unmet need in patients with cancer 

      Vagnildhaug, Ola Magne; Balstad, Trude Rakel; Almberg, Sigrun Saur; Brunelli, Cinzia; Knudsen, Anne Kari; Kaasa, Stein; Thronæs, Morten; Laird, Barry J; Solheim, Tora Skeidsvoll (Journal article; Peer reviewed, 2017)
      Purpose The semantics of defining cancer cachexia over the last decade has resulted in uncertainty as to the prevalence. This has further hindered the recognition and subsequent treatment of this condition. Following the ...
    • A prospective study examining cachexia predictors in patients with incurable cancer 

      Vagnildhaug, Ola Magne; Brunelli, Cinzia; Hjermstad, Marianne Jensen; Strasser, Florian; Baracos, Vickie; Wilcock, Andrew; Nabal, María; Kaasa, Stein; Laird, Barry J; Solheim, Tora Skeidsvoll (Journal article; Peer reviewed, 2019)
      Background Early intervention against cachexia necessitates a predictive model. The aims of this study were to identify predictors of cachexia development and to create and evaluate accuracy of a predictive model based ...
    • Combining optimal nutrition and exercise in a multimodal approach for patients with active cancer and risk for losing weight: Rationale and practical approach 

      Solheim, Tora Skeidsvoll; Vagnildhaug, Ola Magne; Laird, Barry J; Balstad, Trude Rakel (Journal article; Peer reviewed, 2019)
      Weight loss and functional decline is a common and detrimental consequence of cancer. The interventions that are offered to patients with weight loss and functional decline often seem haphazard and varying from center to ...
    • Is it possible to detect an improvement in cancer pain management? A comparison of two Norwegian cross-sectional studies conducted 5 years apart. 

      Thronæs, Morten; Raj, Sunil; Brunelli, Cinzia; Almberg, Sigrun Saur; Vagnildhaug, Ola Magne; Bruheim, Susanna; Helgheim, Birgit; Kaasa, Stein; Knudsen, Anne Kari (Journal article; Peer reviewed, 2016)
      Purpose: Cancer pain (CP) management is challenging. In recent years, efforts were undertaken to achieve better CP management, e.g. clinical research, new treatment modalities, development of guidelines, education, and ...
    • Pain management index (PMI)-does it reflect cancer patients? wish for focus on pain? 

      Thronæs, Morten; Balstad, Trude Rakel; Brunelli, Cinzia; Løhre, Erik Torbjørn; Klepstad, Pål; Vagnildhaug, Ola Magne; Kaasa, Stein; Knudsen, Anne Kari; Solheim, Tora Skeidsvoll (Journal article; Peer reviewed, 2019)
      Background The pain management index (PMI) was developed to combine information about the prescribed analgesics and the self-reported pain intensity in order to assess physicians’ response to patients’ pain. However, ...
    • Physical function endpoints in cancer cachexia clinical trials: Systematic Review 1 of the cachexia endpoints series 

      McDonald, James; Sayers, Judith; Anker, Stefan D.; Arends, Jann; Balstad, Trude Rakel; Baracos, Vickie; Brown, Leo; Bye, Asta; Dajani, Olav; Dolan, Ross; Fallon, Marie T.; Fraser, Eilidh; Griel, Christine; Grzyb, Aleksandra; Hjermstad, Marianne Jensen; Jamal-Hanjani, Mariam; Jakobsen, Gunnhild; Kaasa, Stein; McMillan, Donald; Maddocks, Matthew; Philips, Iain; Ottestad, Inger; Reid, Kieran F.; Sousa, Mariana S.; Simpson, Melanie Rae; Vagnildhaug, Ola Magne; Skipworth, Richard J. E.; Solheim, Tora S; Laird, Barry J (Peer reviewed; Journal article, 2023)
      In cancer cachexia trials, measures of physical function are commonly used as endpoints. For drug trials to obtain regulatory approval, efficacy in physical function endpoints may be needed alongside other measures. However, ...
    • Prevalence, early detection and classification of cancer cachexia 

      Vagnildhaug, Ola Magne (Doktoravhandlinger ved NTNU;2019:334, Doctoral thesis, 2019)
      Cancer cachexia is characterized by loss of muscle mass accompanied by a variable loss of fat mass. It leads to a decline in physical function and quality of life, and an increase in psychological distress and mortality. ...
    • The applicability of a weight loss grading system in cancer cachexia: a longitudinal analysis 

      Vagnildhaug, Ola Magne; Blum, David; Wilcock, Andrew; Fayers, Peter; Strasser, Florian; Baracos, Vickie E.; Hjermstad, Marianne Jensen; Kaasa, Stein; Laird, Barry J; Solheim, Tora Skeidsvoll (Journal article; Peer reviewed, 2017)
      Background A body mass index (BMI) adjusted weight loss grading system (WLGS) is related to survival in patients with cancer. The aim of this study was to examine the applicability of the WLGS by confirming its prognostic ...
    • The Palliative Radiotherapy and Inflammation Study (PRAIS) - Protocol for a longitudinal observational multicenter study on patients with cancer induced bone pain 11 Medical and Health Sciences 1103 Clinical Sciences 

      Habberstad, Ragnhild H; Frøseth, Trude Camilla Salvesen; Aass, Nina Kathrine; Abramova, Tatiana Mikhailovna; Baas, Theo; Mørkeset, Siri Tessem; Caraceni, Augusto; Laird, Barry J; Boland, Jason W.; Rossi, Romina; Garcia-Alonso, Elena; Stensheim, Hanne; Loge, Jon Håvard; Hjermstad, Marianne Jensen; Bjerkeset, Ellen; Bye, Asta; Lund, Jo-Åsmund; Solheim, Tora Skeidsvoll; Vagnildhaug, Ola Magne; Brunelli, Cinzia; Damås, Jan Kristian; Mollnes, Tom Eirik; Kaasa, Stein; Klepstad, Pål (Journal article; Peer reviewed, 2018)
      Background Radiation therapy (RT) results in pain relief for about 6 of 10 patients with cancer induced bone pain (CIBP) caused by bone metastases. The high number of non-responders, the long median time from RT to pain ...
    • Top Ten Tips Palliative Care Clinicians Should Know About Cachexia 

      Blum, David; Vagnildhaug, Ola Magne; Stene, Guro Birgitte; Maddocks, Matthew; Sørensen, Jonas; Laird, Barry J; Prado, Carla M.; Solheim, Tora S; Arends, Jann; Hopkinson, Jane; Jones, Christopher A.; Schlögl, Mathias (Peer reviewed; Journal article, 2023)
      Cachexia is a multifactorial syndrome that is common in cancer and chronic disease. It is often underdiagnosed and therefore goes untreated or undertreated. Cachexia causes suffering across biopsychosocial domains and ...