Blar i Institutt for klinisk og molekylær medisin på forfatter "Sakshaug, Teri"
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Age- and sex-dependent effects of DNA glycosylase Neil3 on amyloid pathology, adult neurogenesis, and memory in a mouse model of Alzheimer's disease
Egiazarian, Milena Armenovna; Strømstad, Silje; Sakshaug, Teri; Nunez-Nescolarde, Ana; Bethge, Nicole; Bjørås, Magnar; Scheffler, Katja (Peer reviewed; Journal article, 2022)Oxidative stress generating DNA damage has been shown to be a key characteristic in Alzheimer's disease (AD). However, how it affects the pathogenesis of AD is not yet fully understood. Neil3 is a DNA glycosylase initiating ... -
The regulation of neuroinflammation by oxidative DNA base lesion repair
Sakshaug, Teri (Master thesis, 2020)Current research shows that altered microglia activity and persistent neuroinflammation are underlying factors to neurological diseases such as Alzheimer's, Parkinson's, multiple sclerosis and psychiatric illnesses. ...