Blar i Institutt for klinisk og molekylær medisin på forfatter "Saito, Takaya"
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A two-step site and mRNA-level model for predicting microRNA targets
Saito, Takaya; Sætrom, Pål (Journal article; Peer reviewed, 2010)Background: Despite experiments showing that the number of microRNA (miRNA) target sites is critical for miRNA targeting, most existing methods focus on identifying individual miRNA target sites and do not model contributions ... -
Computational analysis of regulatory mechanism and interactions of microRNAs
Saito, Takaya (Doktoravhandlinger ved NTNU, 1503-8181; 2011:314, Doctoral thesis, 2011)For years, RNAs were thought to have only two broad functions in cells, transmitting information between DNA and protein as messenger RNA (mRNA), and playing structural, catalytic, information decoding roles in protein ... -
Inferring causative variants in microRNA target sites
Thomas, Laurent; Saito, Takaya; Sætrom, Pål (Journal article; Peer reviewed, 2011)MicroRNAs (miRNAs) regulate genes post transcription by pairing with messenger RNA (mRNA). Variants such as single nucleotide polymorphisms (SNPs) in miRNA regulatory regions might result in altered protein levels and ...