Blar i Institutt for klinisk og molekylær medisin på forfatter "Balluff, Benjamin"
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An optimized MALDI MSI protocol for spatial detection of tryptic peptides in fresh frozen prostate tissue
Høiem, Therese Stork; Andersen, Maria Karoline; Martin-Lorenzo, Marta; Longuespée, Rémi; Claes, Britt S.R.; Nordborg, Anna; Dewez, Frédéric; Balluff, Benjamin; Giampà , Marco; Sharma, Animesh; Hagen, Lars; Heeren, Ron M.A.; Bathen, Tone Frost; Giskeødegård, Guro F.; Krossa, Sebastian; Tessem, May-Britt (Peer reviewed; Journal article, 2022)MALDI MS imaging (MSI) is a powerful analytical tool for spatial peptide detection in heterogeneous tissues. Proper sample preparation is crucial to achieve high quality, reproducible measurements. Here we developed an ... -
Simultaneous Detection of Zinc and Its Pathway Metabolites Using MALDI MS Imaging of Prostate Tissue
Andersen, Maria Karoline; Krossa, Sebastian; Høiem, Therese Stork; Buchholz, Rebecca; Claes, Britt S.R.; Balluff, Benjamin; Ellis, Shane; Richardsen, Elin; Bertilsson, Helena; Heeren, Ron M.A.; Bathen, Tone Frost; Karst, Uwe; Giskeødegård, Guro F.; Tessem, May-Britt (Journal article; Peer reviewed, 2020)Levels of zinc, along with its mechanistically related metabolites citrateand aspartate, are widely reported as reduced in prostate cancer compared to healthytissue and are therefore pointed out as potential cancer biomarkers. ... -
Spatial differentiation of metabolism in prostate cancer tissue by MALDI-TOF MSI
Andersen, Maria Karoline; Høiem, Therese Stork; Claes, Britt S.R.; Balluff, Benjamin; Marta, Martin-Lorenzo; Richardsen, Elin; Krossa, Sebastian; Bertilsson, Helena; Heeren, Ron M.A.; Rye, Morten Beck; Giskeødegård, Guro F.; Bathen, Tone Frost; Tessem, May-Britt (Peer reviewed; Journal article, 2021)Background Prostate cancer tissues are inherently heterogeneous, which presents a challenge for metabolic profiling using traditional bulk analysis methods that produce an averaged profile. The aim of this study was ...