Blar i Institutt for klinisk og molekylær medisin på tittel
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Effects of doxorubicin on cell death and the transcriptome in human AC16 cardiomyocytes
(Master thesis, 2022)Bakgrunn: Kreft og hjarte- og karsjukdom er leiande dødsårsaker i verda. Doxorubicin er mykje nytta som cellegift i kreftbehandling, men utvikling av kardiotoksisitet avgrensar bruken. Faktorar som bidreg til doxorubicin-indusert ... -
Effects of duodenal switch alone or in combination with sleeve gastrectomy on body weight and lipid metabolism in rats
(Journal article; Peer reviewed, 2014)Background: A combined procedure of sleeve gastrectomy and duodenal switch (SG+DS) has been applied to the treatment of super obesity. The aim of the present study was to test whether duodenal switch alone (DS) leads to ... -
Effects of exercise intensity and nutrition advice on myocardial function in obese children and adolescents: a multicentre randomised controlled trial study protocol.
(Journal article; Peer reviewed, 2016)Introduction The prevalence of paediatric obesity is increasing, and with it, lifestyle-related diseases in children and adolescents. High-intensity interval training (HIIT) has recently been explored as an alternate to ... -
Effects of FKBP12-degrading PROTACs on receptor-specific TGF-β signaling in multiple myeloma
(Master thesis, 2021)Abstract Background and aims: Multiple myeloma (MM) is a form of cancer caused by the proliferation of aberrant plasma cells. Myeloma cells are addicted to the MYC oncogene, and this research group has previously shown ... -
Effects of gamma radiation sterilization on the structural and biological properties of decellularized corneal xenografts
(Journal article; Peer reviewed, 2019)To address the shortcomings associated with corneal transplants, substantial efforts have been focused on developing new modalities such as xenotransplantion. Xenogeneic corneas are anatomically and biomechanically similar ... -
Effects of hexyl aminolevulinate and Amphinex based photodynamic therapy and photochemical internalization - in vitro studies using rat bladder cancer cells
(Master thesis, 2011)Photodynamic therapy (PDT) is a treatment modality which involves application of photosensitizers and their ability to accumulate selectively and damage cancer cells in presence of light. Light induced damage to cancer ... -
Effects of High Intensity Interval Training and Strenght Training on Metabolic, Cardiovascular and Hormonal Outcomes in Women with Polycystic Ovary Syndrome: A Pilot Study
(Journal article; Peer reviewed, 2015)Background: Polycystic ovary syndrome is a common endocrinopathy in reproductive-age women, and associates with insulin resistance. Exercise is advocated in this disorder, but little knowledge exists on the optimal ... -
Effects of hypoxia/reoxygenation and miR-24-3p in human cardiomyocyte models
(Master thesis, 2020)Background: Effective cardioprotective therapies targeting the reperfusion phase of ischemia/reperfusion (I/R) injury are lacking, which remain one of the top unmet clinical needs in cardiology. MicroRNAs (miRNAs) are a ... -
Effects of lost microRNA regulation at the global and single gene level in mammalian cells
(Doctoral thesis at NTNU;2014:307, Doctoral thesis, 2014) -
Effects of overexpressing NOR-1 on cell death and cell viability in human cardiomyocytes during doxorubicin-induced stress
(Master thesis, 2021)Koronar hjertesykdom er den ledende dødsårsaken i verden, karakterisert av redusert blodforsyning til hjertet. Ubehandlet kan dette føre til en fullstendig blokkering av koronararteriene, kjent som et hjerteinfarkt. ... -
Effects of photodynamic therapy by TPCS2a on glioma cell lines - in vitro and in vivo studies
(Master thesis, 2021)Ondartet glioma er en alvorlig sykdom som ofte er forbundet med en dårlig prognose. Fotodynamisk terapi (PDT) og fotokjemisk internalisering (PCI) er lovende terapeutiske prinsipper for økende eekt av gliomabehandling, ... -
Effects of Photodynamic Therapy on Protein Expressionin Rat Bladder Cancer Cells
(Master thesis, 2010)Photodynamic therapy (PDT) is an effective treatment involving light and a photosensitizer used in conjunction with molecular oxygen to elicit cell death. The purpose of this study is search for changes in protein expression ... -
Effects of Probiotic Supplementation on the Gut Microbiota and Antibiotic Resistome Development in Preterm Infants
(Journal article; Peer reviewed, 2018)Objectives: In 2014 probiotic supplementation (Lactobacillus acidophilus and Bifidobacterium longum subspecies infantis; Infloran®) was introduced as standard of care to prevent necrotizing enterocolitis (NEC) in extremely ... -
Effects of Purple Coneflower (Echinacea purpurea) on CYP3A4 Metabolism and P-glycoprotein Mediated Transport in Vitro
(Doctoral Theses at NTNU, 1503-8181; 2012:365, Doctoral thesis, 2012)Solhatt har blitt et av de vanligste urtepreparatene på verdensmarkedet, og markedsføres for sin effekt mot luftveisinfeksjoner og forkjølelse. Sambruk av naturpreparater og legemidler forekommer ofte, og det er kjent at ... -
Effects of race and ethnicity on perinatal outcomes in high-income and upper-middle-income countries: an individual participant data meta-analysis of 2 198 655 pregnancies
(Peer reviewed; Journal article, 2022)Background Existing evidence on the effects of race and ethnicity on pregnancy outcomes is restricted to individual studies done within specific countries and health systems. We aimed to assess the impact of race and ... -
The Effects of Shift Work on the Immune System: A Narrative Review
(Peer reviewed; Journal article, 2023)Working a shift work schedule has been hypothesized to have negative effects on health. One such described consequence is altered immune response and increased risk of infections. Former reviews have concluded that more ... -
Effects of Single-nucleotide Polymorphisms on microRNA-Based Gene Regulation and Their Association With Disease
(Doktoravhandlinger ved NTNU, 1503-8181; 2012:307, Doctoral thesis, 2012)Effekter av enkeltnukleotidpolymorfismer på mikroRNA-basert genregulering og deres assosiasjon med sykdom DNA-et inneholder variasjoner mellom individer, og DNA-varianter slik som enkeltnukleotidpolymorfismer (SNP) kan ... -
Effects of supervised exercise training during pregnancy on psychological well-being among overweight and obese women: secondary analyses of the ETIP-trial, a randomised controlled trial
(Journal article; Peer reviewed, 2019)Objectives Women with high body mass index (BMI) have increased risk for symptoms of anxiety and depression during pregnancy and postpartum. In this prespecified secondary analysis from the exercise training in pregnancy ... -
Effects of vitamin D supplementation on bone turnover markers and other bone-related substances in subjects with vitamin D deficiency
(Journal article; Peer reviewed, 2019)In observational studies, vitamin D deficiency is a risk factor for low bone density and future fractures, whereas a causal relation has been difficult to show in randomized controlled trials (RCTs). Similarly, vitamin D ... -
Effects of “exercised plasma” on adult neurogenesis in the hippocampus of a rat model of Alzheimer’s disease
(Master thesis, 2021)Forekomsten av demens øker i sammenheng med den økende andelen eldre befolkning. I dag finnes det ingen behandlingsmuligheter for demenssykdommen med høyest prevalens, Alzheimers sykdom. For å hindre en potensiell internasjonal ...