Blar i Institutt for klinisk og molekylær medisin på tittel
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DNA repair enzyme NEIL3 enables a stable neural representation of space by shaping transcription in hippocampal neurons
(Peer reviewed; Journal article, 2021)DNA repair enzymes are essential for the maintenance of the neuronal genome and thereby proper brain functions. Emerging evidence links DNA repair to epigenetic gene regulation; however, its contribution to different ... -
DNA Repair Mechanisms are Activated in Circulating Lymphocytes of Hospitalized Covid-19 Patients
(Peer reviewed; Journal article, 2022)Purpose: Reactive oxygen species (ROS) are an important part of the inflammatory response during infection but can also promote DNA damage. Due to the sustained inflammation in severe Covid-19, we hypothesized that ... -
DNA repair protein complexes, functionality and significance for repair efficiency and cell survival
(Doktoravhandlinger ved NTNU, 1503-8181; 2010:146, Doctoral thesis, 2010)DNA‐reparasjons‐protein‐komplekser, funksjonalitet og signifikans for reparasjonseffektivitet og skadetoleranse All informasjon om en organisme er lagret i vår arvestoff, DNA. DNA er et relativt ustabilt makromolekyl som ... -
DNA topoisomerase IIα and mitosin expression predict meningioma recurrence better than histopathological grade and MIB-1 after initial surgery
(Journal article; Peer reviewed, 2017)Background: The 2016 WHO histopathological grade or conventional biomarker MIB-1 is insufficient for predicting meningioma recurrence after initial treatment and alternative strategies are required. In this study, we ... -
DNA-basert overvåking av den skandinaviske jervbestanden 2008-2011
(NINI rapport;843, Research report, 2012)Genetiske analyser er de siste årene blitt implementert som et viktig verktøy i rovviltovervåkingen i Skandinavia. I særlig grad har antallet DNA-analyser av ekskrementer økt betydelig. Det siste tiåret er det gjennomført ... -
Do changes in persistent organic pollutants after bariatric surgery cause endocrine disruption?
(Peer reviewed; Journal article, 2022)Do changes in persistent organic pollutants after bariatric surgery cause endocrine disruption? -
Do children with cerebral palsy benefit from computerized working memory training? Study protocol for a randomized controlled trial
(Journal article; Peer reviewed, 2014)Background Cerebral palsy (CP) is the most common motor disability in childhood (2 to 3 per 1000 live births), and is frequently accompanied by cognitive impairments and behavioural problems. Children with CP are at ... -
Do Gastric Signet Ring Cell Carcinomas and ECL‐Cell Neuroendocrine Tumours Have a Common Origin?
(Peer reviewed; Journal article, 2022)Gastric cancer is a heterogenous group of tumours, and a better understanding of the carcinogenesis and cellular origin of the various sub-types could affect prevention and future treatment. Gastric neuroendocrine tumours ... -
Do laws impact opioids consumption? A breakpoint analysis based on italian sales data
(Journal article; Peer reviewed, 2018)Purpose: In Italy, where the adoption of opioid analgesics in pain management has been historically poor, an increase in opioids consumption occurred between 2000 and 2015. The aim of this study is to assess, through ... -
Do Norwegians with diabetes have a healthier diet than the general population?
(Journal article; Peer reviewed, 2013)Objective: Review current knowledge about dietary habits among people with diabetes in Norway compared with the general population and nutrient- and food-based dietary recommendations. Method: Baseline dietary data from ... -
Do patients with gastroesophageal reflux disease exhibit compromised bone quality prior to proton pump inhibitor therapy?
(Peer reviewed; Journal article, 2021)Patients with gastroesophageal reflux disease (GERD) are routinely treated with proton pump inhibitors (PPIs), despite many reports of increased fracture risk associated with PPI use. Notably, the skeletal properties in ... -
Do Sexually Abstinent Women have more pelvic floor Disorders?A cross sectional, population based study
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Does a parent-administrated early motor intervention influence general movements and movement character at 3 months of age in infants born preterm?
(Journal article; Peer reviewed, 2017)Background Studies of preterm and term-born infants have shown absent fidgety movements and an abnormal movement character to be related to brain lesions and unfavourable neurological outcomes. Aims The present study ... -
Does AMH Reflect Follicle Number Similarly in Women with and without PCOS?
(Journal article; Peer reviewed, 2016-01-22)Context: Increased Anti-Mullerian Hormone in polycystic ovary syndrome, may be due to overactive follicles rather than reflect antral follicle count. Objective: Does Anti-Mullerian Hormone reflect antral follicle ... -
Does caesarean delivery in the first pregnancy increase the risk for adverse outcome in the second? A registry-based cohort study on first and second singleton births in Norway
(Peer reviewed; Journal article, 2020)Objective To explore if newborns in the second pregnancy following a previous caesarean delivery (CD) have higher risk of perinatal mortality or cerebral palsy than newborns in pregnancies following a previous vaginal ... -
Does Metformin Treatment during Pregnancy Modify the Future Metabolic Profile in Women with PCOS?
(Journal article; Peer reviewed, 2018)Context Worldwide, metformin is prescribed to improve pregnancy outcome in polycystic ovary syndrome (PCOS). Metformin may also benefit future health by modulating increased metabolic stress during pregnancy. Objective To ... -
Does Prophylactic Radiation Therapy to Avoid Gynecomastia in Patients With Prostate Cancer Increase the Risk of Breast Cancer?
(Journal article; Peer reviewed, 2018)Purpose Prostate cancer (PC) patients who undergo antiandrogen monotherapy are offered prophylactic radiation therapy (PRT) to the breast buds to avoid gynecomastia. The aim of the present study was to evaluate whether ... -
Does treatment with bisphosphonates protect against fractures in real life? The HUNT study, Norway
(Peer reviewed; Journal article, 2021)Summary Bisphosphonates reduce fractures in randomized controlled trials (RCT); however, there is less information from real life. In our population including 14,990 women and 13,239 men, use of bisphosphonates reduced ... -
Dopamine D2 receptor C957T polymorphism and its phenotypic consequences on executive functions in 8 years old children
(Master thesis, 2015)Executive functions (EFs) are a set of cognitive skills that allows goal oriented behaviour. Three principal skills - inhibition, working memory and set-shifting - are thought to modulate higher level functions, such as ...