Blar i Institutt for klinisk og molekylær medisin på tittel
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Development of a CRISPR/Cas9 knockout-complementation system for application in HIV host dependency factor analysis.
(Master thesis, 2020)Over the past two decades, substantial research has produced a vast array of HIV treatments. However, the rapid mutation rate of the virus has lead to high drug resistance against the treatments. To combat the rapid mutations ... -
Development of a deep inspiration breath-hold system for radiotherapy utilizing a laser distance measurer
(Journal article; Peer reviewed, 2017)Deep inspiration breath‐hold (DIBH) is a technique for treating left‐sided breast cancer (LSBC). In modern radiotherapy, one of the main aims is to exclude the heart from the beam aperture with an individualized beam design ... -
Development of a rapid and simplified protocol for direct bacterial identification from positive blood cultures by using matrix assisted laser desorption ionization time-of- flight mass spectrometry.
(Peer reviewed; Journal article, 2015)Background Bloodstream infections represent serious conditions carrying a high mortality and morbidity rate. Rapid identification of microorganisms and prompt institution of adequate antimicrobial therapy is of utmost ... -
Development of a Spectral Library for the Discovery of Altered Genomic Events in Mycobacterium avium Associated With Virulence Using Mass Spectrometry-Based Proteogenomic Analysis
(Peer reviewed; Journal article, 2023)Mycobacterium avium is one of the prominent disease-causing bacteria in humans. It causes lymphadenitis, chronic and extrapulmonary, and disseminated infections in adults, children, and immunocompromised patients. M. avium ... -
Development of a tailored microfluidic platform with improved electrical signal detection for in vitro studies of neural networks and neural network pathology
(Master thesis, 2020)Menneskets nervesystem utgjør verdens mest avanserte evolusjonære maskineri. Gjennom dets høyst intrikate arkitektur og beregningsevner kontrollerer det oppgaver så funksjonelt forskjellige som muskelbevegelser og lagring ... -
Development of an Effective Method for Studying Pancreatic Cancer: Formation of Spheroids in 3D Culture
(Master thesis, 2021)Pancreatic cancer, particularly pancreatic ductal adenocarcinoma (PDAC), is a highly fatal malignancy and the tumor microenvironment plays an important role in its tumorigenesis. The improvement of treatment methods has ... -
Development of an improved pathway analysis - The FunHop story
(Doctoral theses at NTNU;2022:212, Doctoral thesis, 2022)Norsk sammendrag Arbeidet som presenteres i denne avhandlingen omhandler metabolisme i prostatakreft, hovedsakelig i form av bruk og forbedring av analyse av biologiske spor. En stor del av oppgaven handler om utvikling ... -
Development of bimanual performance in young children with cerebral palsy
(Journal article; Peer reviewed, 2018)Aim To describe the development of bimanual performance among young children with unilateral or bilateral cerebral palsy (CP). Method A population‐based sample of 102 children (53 males, 49 females), median age 28.5 ... -
Development of EirV3 - a computer-based tool for patient reported outcome measures in cancer
(Journal article; Peer reviewed, 2017)Purpose Immediate transfer of patient-reported outcome measures (PROMs) for use in medical consultations is facilitated by electronic assessments. We aimed to describe the rationale and development of Eir version 3 (EirV3), ... -
Development of hippocampal subfield volumes from 4 to 22 years
(Journal article; Peer reviewed, 2014-06-30)The hippocampus supports several important cognitive functions known to undergo substantial development during childhood and adolescence, e.g. encoding and consolidation of vivid personal memories. However, diverging ... -
Development of non-injectable naloxone for pre-hospital reversal of opioid overdoses: A Norwegian project and a review of international status
(Master thesis, 2016)Background and aims: Per year, overdoses kill 69.000 users of illicit and prescription opioids in epidemic pattern worldwide. Among them, 250 people in Norway. Naloxone is an effective antidote for opioid overdose reversal, ... -
Development of Parvalbumin-Expressing Basket Terminals in Layer II of the Rat Medial Entorhinal Cortex
(Journal article; Peer reviewed, 2018)Grid cells in layer II of the medial entorhinal cortex (MEC LII) generate multiple regular firing fields in response to the position and speed of an individual within the environment. They exhibit a protracted postnatal ... -
Development of strategies to identify new psychoactive substances and their metabolites in biological samples by LC-QTOF-MS technology
(Doctoral theses at NTNU;2020:303, Doctoral thesis, 2020)New psychoactive substances (NPS) are emerging in the illegal drug market, which has led to major challenges for analytical laboratories. Keeping screening methods up to date with all relevant drugs is hard to achieve and ... -
Development of the EORTC QLQ-CAX24, A Questionnaire for Cancer Patients With Cachexia
(Journal article; Peer reviewed, 2017)Context Cachexia is commonly found in cancer patients and has profound consequences; yet there is only one questionnaire that examines the patient's perspective. Objective To report a rigorously developed module for ... -
Developmental Course and Risk Factors of Physical Aggression in Late Adolescence
(Peer reviewed; Journal article, 2020)This study examined risk factors of physical aggression during transition from early to late adolescence using a two-wave longitudinal study. Specifically, we examined if risk factors in early adolescence predict physically ... -
Developmental Origins of Disease: Influence of low birth weight and maternal vitamin A and D status on offspring skeletal health and metabolic outcomes at adulthood
(Doctoral theses at NTNU;2018:221, Doctoral thesis, 2018)Developmental origins of adult health and disease (DOHaD) has gained increased attention during the past few decades. Birth size reflects the prenatal environment, and there is substantial evidence that low birth weight ... -
DHA-induced sensitization of colon cancer cells to chemotherapeutic agents – Signalling pathways involved
(Master thesis, 2019)Increased intake of n-3 PUFAs, such as docosahexaenoic acid (DHA;22:6n-3) could be beneficial in cancer therapy as it has been shown to exhibit several anti-cancer effects, including alteration of eicosanoid synthesis, ... -
DHA-induced stress response in human colon cancer cells - Focus on oxidative stress and autophagy
(Journal article; Peer reviewed, 2016)Polyunsaturated fatty acids (PUFAs) are important constituents of the diet and health benefits of omega-3/n−3 PUFAs, especially eicosapentaenoic acid (EPA, 20:5 n−3) and docosahexaenoic acid (DHA, 22:6 n−3) have been well ... -
DHA-induced stress response in human colon cancer cells - Focus on oxidative stress and autophagy
(Journal article; Peer reviewed, 2016) -
Diabetes Prevalence and Associated Risk Factors among Women in a Rural District of Nepal Using HbA1c as a Diagnostic Tool: A Population-Based Study
(Peer reviewed; Journal article, 2022)Given the scarcity of data on diabetes prevalence and associated risk factors among women in rural Nepal, we aimed to examine this, using glycated hemoglobin (HbA1c) as a diagnostic tool. A cross-sectional survey addressing ...