Blar i Institutt for klinisk og molekylær medisin på tittel

Viser treff 367-386 av 3426

    • Breakthrough and Episodic Cancer Pain from a Palliative Care Perspective 

      Løhre, Erik Torbjørn; Jakobsen, Gunnhild; Solheim, Tora Skeidsvoll; Klepstad, Pål; Thronæs, Morten (Peer reviewed; Journal article, 2023)
      Cancer pain intensity (PI) fluctuates, but the relationship between pain flares and background pain with respect to pain management is not settled. We studied how flare and background PIs corresponded with treatment results ...

    • Breakthrough cancer pain in 2020 

      Løhre, Erik T; Thronæs, Morten; Klepstad, Pål (Peer reviewed; Journal article, 2020)
      Purpose of review An overview on breakthrough cancer pain (BTCP), including inherent limitations of the terminology, assessment, clinical presentation, and treatment options. Recent findings The estimated prevalence ...

    • Breast Cancer Patients’ Experiences with Information and Communication in Cancer Disease Trajectories 

      Brattheim, Berit J; Sand, Kari; Gilstad, Heidi; Stalsberg, Ragna; Lundgren, Steinar; Reidunsdatter, Randi Johansen (Journal article; Peer reviewed, 2017)
      Patients’ experiences have been used as an indicator for hospital quality for a long time. The concept of patient experiences has many facets. One aspect of particular importance for optimal treatment and patients’ quality ...

    • Breeze 2.0: An interactive web-tool for visual analysis and comparison of drug response data 

      Potdar, Swapnil; Ianevski, Filipp; Ianevski, Aleksandr; Tanoli, Ziaurrehman; Wennerberg, Krister; Seashore-Ludlow, Brinton; Kallioniemi, Olli; Ostling, Paivi; Aittokallio, Tero Antero; Saarela, Jani (Peer reviewed; Journal article, 2023)
      Functional precision medicine (fPM) offers an exciting, simplified approach to finding the right applications for existing molecules and enhancing therapeutic potential. Integrative and robust tools ensuring high accuracy ...

    • Brief Report: The Genetic Profile of Rheumatoid Factor?Positive Polyarticular Juvenile Idiopathic Arthritis Resembles That of Adult Rheumatoid Arthritis 

      Hinks, Anne; Marion, Miranda C.; Cobb, Joanna; Comeau, Mary E.; Sudman, Marc; Ainsworth, Hannah C.; Bowes, John; Becker, Mara L.; Bohnsack, John F.; Haas, Johannes-Peter; Lovell, Daniel J.; Mellins, Elizabeth D.; Nelson, J. Lee; Nordal, Ellen Berit; Punaro, Marilynn; Reed, Ann M.; Rose, Carlos D.; Rosenberg, Alan M.; Rygg, Marite; Smith, Samantha L.; Stevens, Anne M.; Videm, Vibeke; Wallace, Carol A.; Wedderburn, Lucy R.; Yarwood, Annie; Yeung, Rae S.M.; Langefeld, Carl D.; Thompson, Susan D.; Thomson, Wendy; Prahalad, Sampath (Journal article; Peer reviewed, 2018)

    • Broad-Spectrum Antibacterial Peptide Kills Extracellular and Intracellular Bacteria Without Affecting Epithelialization 

      Nepal, Anala; Ræder, Synnøve Brandt; Søgaard, Caroline Krogh; Haugan, Maria Schei; Otterlei, Marit (Peer reviewed; Journal article, 2021)
      New antibacterial drugs with novel modes of action are urgently needed as antibiotic resistance in bacteria is increasing and spreading throughout the world. In this study, we aimed to explore the possibility of using ...

    • Broad-Spectrum Antiviral monotherapies: in silico drug repositioning against emergent viruses 

      Simonsen, Ronja Meyer (Master thesis, 2022)
      Utbruddet av SARS-CoV-2 har demonstrert realiteten av globale virale trusler. SARS-CoV-2 krysset arts barrierer og forårsaket en pandemi som verden ikke var forberedt på. Antiviraler er medikamenter som hemmer formeringen ...

    • Broadly neutralizing humanized SARS-CoV-2 antibody binds to a conserved epitope on Spike and provides antiviral protection through inhalation-based delivery in nonhuman primates 

      Hermet, Paule; Delache, Benoît; Herate, Cecile; Wolf, Esther; Kivi, Gaily; Juronen, Erkki; Mumm, Karl; Žusinaite, Eva; Kaynov, Denis; Sankovski, Eve; Virumäe, Kai; Planken, Anu; Merits, Andres; Besaw, Jessica E.; Yee, Ai Woon; Morizumi, Takefumi; Kim, Kyumhyuk; Kuo, Anling; Berriche, Asma; Dereuddre-Bosquet, Nathalie; Sconosciuti, Quentin; Naninck, Thibaut; Relouzat, Francis; Cavarelli, Mariangela; Wilson, Derek; Ernst, Oliver P.; Männik, Andres; LeGrand, Roger; Ustav, Mart (Peer reviewed; Journal article, 2023)
      The COVID-19 pandemic represents a global challenge that has impacted and is expected to continue to impact the lives and health of people across the world for the foreseeable future. The rollout of vaccines has provided ...

    • Bronchial microdialysis monitoring of inflammatory response in open abdominal aortic aneurysm repair; an observational study. 

      Tyvold, Stig Sverre; Dahl, Torbjørn; Dragsund, Stein; Gunnes, Sigurd; Lyng, Oddveig; Damås, Jan Kristian; Aadahl, Petter; Solligård, Erik (Journal article; Peer reviewed, 2017)
      Aortic surgery results in ischemia–reperfusion injury that induces an inflammatory response and frequent complications. The magnitude of the inflammatory response in blood and bronchi may be associated with the risk of ...

    • Bronchoalveolar lavage fluid IFN- γ + Th17 cells and regulatory T cells in pulmonary sarcoidosis 

      Tøndell, Anders; Moen, Torolf; Børset, Magne; Salvesen, Øyvind; Rø, Anne Dorthea; Sue-Chu, Malcolm (Journal article; Peer reviewed, 2014)
      In sarcoidosis, increased Th17 cell fractions have been reported in bronchoalveolar lavage fluid, and elevated numbers of Th17 cells producing IFN-𝛾 have been observed in peripheral blood. The balance between Th1, Th17, ...

    • Bruk av botulinumtoksin A til barn med cerebral parese 

      Ross Raftemo, Anne Elisabeth; Mahendran, Arani; Hollung, Sandra Julsen; Jahnsen, Reidun; Lydersen, Stian; Vik, Torstein; Andersen, Guro Lillemoen (Peer reviewed; Journal article, 2019)
      BAKGRUNN Intramuskulære injeksjoner med botulinumtoksin A har i over 20 år vært en etablert behandling av spastisitet hos barn med cerebral parese. Vi undersøkte hvor mange barn med cerebral parese i Norge som får slik ...

    • Bruk av piperacillin/tazobaktam ved behandling av infeksjoner i abdomen - Kan intervensjoner bidra til å optimalisere forskrivningen? 

      Gustavsen, Ingrid Ressem (Master thesis, 2022)
      Introduksjon: Antibiotikaresistens er en trussel mot folkehelsen. Effektive tiltak for å bremse utviklingen er viktig for å kunne ha effektiv antibiotikabehandling også i fremtiden. De nasjonale retningslinjene for ...

    • Bruk av psykofarmaka der farmakogenetiske analyser er aktuelt 

      Nilsen, Julie Berg (Master thesis, 2022)
      Bakgrunn: En betydelig andel av den norske befolkningen vil rammes av psykiske lidelser i løpet av ett år, og mange vil ha behov for medikamentell behandling med psykofarmaka. Det er imidlertid flere utfordringer knyttet ...

    • Burden of bloodstream infection in an area of Mid-Norway 2002-2013: A prospective population-based observational study 

      Mehl, Arne; Åsvold, Bjørn Olav; Lydersen, Stian; Paulsen, Julie; Solligård, Erik; Damås, Jan Kristian; Harthug, Stig; Edna, Tom-Harald (Journal article; Peer reviewed, 2017)
      Background Studies from several countries indicate that the incidence and mortality of bloodstream infection (BSI) have been increasing over time. Methods We studied the burden of disease and death related to BSI in ...

    • The burden of hospital-attended influenza in Norwegian children 

      Bøås, Håkon; Bekkevold, Terese; Havdal, Lise Beier; Kran, Anne-Marte Bakken; Rojahn, Astrid; Størdal, Ketil; Debes, Sara; Døllner, Henrik; Nordbø, Svein Arne; Barstad, Bjørn; Haarr, Elisebet; Vazquez Fernandez, Liliana; Nakstad, Britt; Leegaard, Truls Michael; Hungnes, Olav; Flem, Elmira (Journal article; Peer reviewed, 2022)

    • The Burden of Human Bocavirus 1 in Hospitalized Children with Respiratory Tract Infections 

      Jalving, Hedda Trømborg ; Heimdal, Inger; Valand, Jonas; Risnes, Kari; Krokstad, Sidsel; Nordbø, Svein Arne; Døllner, Henrik; Christensen, Andreas (Peer reviewed; Journal article, 2023)
      Background Human bocavirus 1 (HBoV1) is frequently codetected with other viruses, and detected in asymptomatic children. Thus, the burden of HBoV1 respiratory tract infections (RTI) has been unknown. Using HBoV1-mRNA ...

    • The Burden of Human Coronavirus in Norwegian Children hospitalized with Respiratory Tract Infections 

      Heimdal, Inger (Doctoral theses at NTNU;2022:359, Doctoral thesis, 2022)

    • The burden of respiratory syncytial virus in children under 5 years of age in Norway 

      Havdal, Lise Beier; Bøås, Håkon; Bekkevold, Terese; Kran, Anne-Marte Bakken; Rojahn, Astrid; Størdal, Ketil; Debes, Sara Molvig; Døllner, Henrik; Nordbø, Svein Arne; Barstad, Bjørn; Haarr, Elisebet; Vazquez Fernandez, Liliana; Nakstad, Britt; Inchley, Christopher; Flem, Elmira (Peer reviewed; Journal article, 2021)
      Abstract Objectives To estimate age-specific incidence of medically attended respiratory syncytial virus (RSV) infections in hospitalised Norwegian children and describe disease epidemiology. Methods Active prospective ...

    • The burden of rheumatoid arthritis - physical fitness, function, and mortality 

      Houge, Ingrid Sæther (Doctoral theses at NTNU;2023:243, Doctoral thesis, 2023)
      Patients with rheumatoid arthritis (RA) have higher mortality rates than the general population as well as lower cardiorespiratory fitness. They also have an increased risk of myocardial infarction of similar magnitudes ...

    • Bypassing adverse injection reactions to nanoparticles through shape modification and attachment to erythrocytes 

      Wibroe, Peter Popp; Anselmo, Aaron C; Nilsson, Per; Sarode, Apoorva; Gupta, Vivek; Urbanics, Rudolf; Szebeni, Janos; Hunter, Alan Christy; Mitragotri, Samir; Mollnes, Tom Eirik; Moghimi, Seyed Moein (Journal article, 2017)
      Intravenously injected nanopharmaceuticals, including PEGylated nanoparticles, induce adverse cardiopulmonary reactions in sensitive human subjects, and these reactions are highly reproducible in pigs. Although the underlying ...