Blar i Institutt for klinisk og molekylær medisin på tittel
Viser treff 258-277 av 3426
-
Associations between muscle measures, survival and toxicity in patients with limited disease small cell lung cancer receiving concurrent chemoradiotherapy
(Peer reviewed; Journal article, 2020)Background Standard treatment for patients with limited stage small cell lung cancer (LS SCLC) is concurrent platinum– etoposide chemotherapy and thoracic radiotherapy (TRT). Up to 30% of patients are cured, but severe ... -
Associations between severe co-morbidity and muscle measures in advanced non-small cell lung cancer patients
(Journal article; Peer reviewed, 2019)Introduction Several studies show that low skeletal muscle index (SMI) and low skeletal muscle density (SMD) are negative prognostic factors and associated with more toxicity from systemic therapy in cancer patients. ... -
Associations between the FTO rs9939609 genotypes and insulin sensitivity, glucose tolerance, energy metabolism, appetite hormones, and diet in patients with severe obesity
(Doctoral theses at NTNU;2022:398, Doctoral thesis, 2022) -
Associations Between Time to Treatment Start and Survival in Patients With Lung Cancer
(Peer reviewed; Journal article, 2021)Background: Time-to-treatment is defined as a quality indicator for cancer care but is not well documented. We investigated whether meeting Norwegian timeframes of 35/42 days from referral until start of chemotherapy or ... -
Associations between tumor mutations in cfDNA and survival in non-small cell lung cancer
(Peer reviewed; Journal article, 2021)Introduction: Studies have indicated that detection of mutated KRAS or EGFR in circulating tumor DNA (ctDNA) from pre-treatment plasma samples is a negative prognostic factor for non-small cell lung cancer (NSCLC) pa-tients. ... -
Associations between unit workloads and outcomes of first extubation attempts in extremely premature infants below a gestational age of 26 weeks
(Peer reviewed; Journal article, 2023)Objective: The objective was to explore whether high workloads in neonatal intensive care units were associated with short-term respiratory outcomes of extremely premature (EP) infants born <26 weeks of gestational ... -
Associations of gene expression in blood with BMI and weight changes among women in the Norwegian Women and Cancer postgenome cohort
(Peer reviewed; Journal article, 2023)Objective This study aimed to evaluate associations between blood gene expression profiles and (1) current BMI and (2) past weight changes (WCs) among women who had never been diagnosed with cancer in the Norwegian Women ... -
Associations of low sex hormone-binding globulin and androgen excess in early pregnancy with fasting and post-prandial hyperglycaemia, gestational diabetes, and its severity
(Peer reviewed; Journal article, 2022)Aims We studied whether androgen excess and low sex hormone-binding globulin (SHBG) measured in early pregnancy are independently associated with fasting and post-prandial hyperglycaemia, gestational diabetes (GDM), and ... -
Associations of Maternal Vitamin B12 Concentration in Pregnancy With the Risks of Preterm Birth and Low Birth Weight: A Systematic Review and Meta-Analysis of Individual Participant Data
(Journal article; Peer reviewed, 2017)Vitamin B12 (hereafter referred to as B12) deficiency in pregnancy is prevalent and has been associated with both lower birth weight (birth weight <2,500 g) and preterm birth (length of gestation <37 weeks). Nevertheless, ... -
Associations of obesity and lifestyle with the risk and mortality of bloodstream infection in a general population: a 15-year follow-up of 64 027 individuals in the HUNT Study
(Journal article; Peer reviewed, 2017)Background: Bloodstream infections (BSI) cause considerable morbidity and mortality, and primary prevention should be a priority. Lifestyle factors are of particular interest since they represent a modifiable target. Methods: ... -
Associations of serum 25-hydroxyvitamin D level with incidence of lung cancer and histologic types in Norwegian adults: a case-cohort analysis of the HUNT study
(Journal article, 2017)Background: Previous prospective studies have shown inconsistent associations between serum 25-hydroxyvitamin D [25(OH)D] level and lung cancer incidence. The aim of the present study was to explore the associations of ... -
Asthma and asthma symptom control in relation to incidence of lung cancer in the HUNT study
(Peer reviewed; Journal article, 2021)Large prospective studies on asthma, especially asthma symptom control, as a potential risk factor for lung cancer are limited. We followed up 62,791 cancer-free Norwegian adults from 1995–1997 to 2017. Self-reported ... -
Astrocytic Ca2+ signaling is reduced during sleep and is involved in the regulation of slow wave sleep
(Peer reviewed; Journal article, 2020)Astrocytic Ca2+ signaling has been intensively studied in health and disease but has not been quantified during natural sleep. Here, we employ an activity-based algorithm to assess astrocytic Ca2+ signals in the neocortex ... -
Atezolizumab and stereotactic body radiotherapy in patients with advanced non-small cell lung cancer: safety, clinical activity and ctDNA responses—the ComIT-1 trial
(Peer reviewed; Journal article, 2022)The introduction of immune checkpoint inhibitors has transformed the treatment landscape of metastatic non-small cell lung cancer. However, challenges remain to increase the fraction of patients achieving durable clinical ... -
Atherosclerotic and obesity-associated inflammation : focus on cholesterol crystals, complement and coagulation
(Master thesis, 2015)Atherosclerosis is a chronic inflammatory disease of the arterial wall, and a leading cause of death worldwide. An emerging role for the complement system in the pathogenesis of atherosclerosis is demonstrated by the ... -
ATM instigate melphalan mediated damage response in multiple myeloma: the tip of the iceberg
(Master thesis, 2021)INNLEDNING: Myelomatose (MM) er en uhelbredelig hematologisk krefttype preget av hyperproliferasjon av plasmaceller. Sykdommens robusthet skyldes utvikling av resistens og tilbakefall av sykdommen. Forekomst av minimal ... -
Atrial Myocyte Function and Ca2+ Handling Is Associated with Inborn Aerobic Capacity
(Peer reviewed; Journal article, 2013-10-16)Background: Although high aerobic capacity is associated with effective cardiac function, the effect of aerobic capacity on atrial function, especially in terms of cellular mechanisms, is not known. We aimed to investigate ... -
ATX-101, a Peptide Targeting PCNA, Has Antitumor Efficacy Alone or in Combination with Radiotherapy in Murine Models of Human Glioblastoma
(Peer reviewed; Journal article, 2022)Cell proliferation requires the orchestrated actions of a myriad of proteins regulating DNA replication, DNA repair and damage tolerance, and cell cycle. Proliferating cell nuclear antigen (PCNA) is a master regulator which ...