Blar i Institutt for klinisk og molekylær medisin på tittel
Viser treff 1998-2017 av 3415
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Metabolomics identifies placental dysfunction and confirms Flt-1 (FMS-like tyrosine kinase receptor 1) biomarker specificity
(Journal article; Peer reviewed, 2019)Clinical end-stage parameters define the pregnancy disorders preeclampsia and fetal growth restriction while classification of the underlying placental dysfunction is missing and urgently needed. Flt-1 (FMS-like tyrosine ... -
Metachronous Contralateral Testicular Cancer in the Cisplatin Era: A Population-Based Cohort Study
(Peer reviewed; Journal article, 2020)PURPOSE It is hypothesized that cisplatin-based chemotherapy (CBCT) reduces the occurrence of metachronous contralateral (second) germ cell testicular cancer (TC). However, studies including treatment details are lacking. ... -
Metacognitive Strategy Training Versus Psychoeducation for Improving Fatigue in Children and Adolescents With Acquired Brain Injuries: A Randomized Controlled Trial
(Journal article; Peer reviewed, 2022) -
Metastatic Cancerous Intestinal Epithelial Cells express Toll-like receptor 3 and release RANTES/CCL5 and IP-10/CXCL10 in response to Double-stranded RNA
(Master thesis, 2011)Toll-like receptors (TLR)s are important for mounting an inflammatory response against invading microorganisms by recognizing pathogen-associated molecular patterns (PAMP)s, which are rare or absent in vertebrates. TLRs ... -
Metformin exposure, maternal PCOS status and fetal venous liver circulation: A randomized, placebo-controlled study
(Peer reviewed; Journal article, 2022)Background Metformin is prescribed to women with polycystic ovary syndrome (PCOS) to prevent pregnancy complications. Children exposed to metformin vs. placebo in utero, have increased head circumference at birth and are ... -
Metformin in pregnancy and long-term health of children of women with polycystic ovary syndrome
(Doctoral theses at NTNU;2019:187, Doctoral thesis, 2019)Metformin i svangerskap og langtidshelse hos barn av mødre med polycystisk ovariesyndrom (PCOS) Polycystisk ovariesyndrom (PCOS) er en vanlig tilstand hos kvinner i fertil alder, med en prevalens på rundt 15%. PCOS gir ... -
Metformin in Pregnancy Study (MiPS): protocol for a systematic review with individual patient data meta-analysis
(Peer reviewed; Journal article, 2020)Introduction: Gestational diabetes mellitus (GDM) is a common disorder of pregnancy and contributes to adverse pregnancy outcomes. Metformin is often used for the prevention and management of GDM; however, its use in ... -
Metformin Therapy Changes Gut Microbiota Alpha-Diversity in COVID-19 Patients with Type 2 Diabetes: The Role of SARS-CoV-2 Variants and Antibiotic Treatment
(Peer reviewed; Journal article, 2023)The gut microbiota play a crucial role in maintaining host health and have a significant impact on human health and disease. In this study, we investigated the alpha diversity of gut microbiota in COVID-19 patients and ... -
Metformin Therapy Changes Gut Microbiota Alpha-Diversity in COVID-19 Patients with Type 2 Diabetes: The Role of SARS-CoV-2 Variants and Antibiotic Treatment
(Peer reviewed; Journal article, 2023)The gut microbiota play a crucial role in maintaining host health and have a significant impact on human health and disease. In this study, we investigated the alpha diversity of gut microbiota in COVID-19 patients and ... -
Methadone pharmacokinetics in opioid agonist treatment: Influencing factors and clinical implications
(Peer reviewed; Journal article, 2024)Background A considerable inter-individual variability has been reported in the relationship between methadone doses applied and serum concentrations achieved in methadone maintenance treatment. However, the underlying ... -
Methodology Matters: Comparing Approaches for Defining Persistent Symptoms after Mild Traumatic Brain Injury
(Peer reviewed; Journal article, 2021)Some people experience persistent post-concussion symptoms (PPCS) after mild traumatic brain injury (mTBI). A meaningful clinical classification and scientific progress are hampered by a lack of consensus regarding the ... -
Methods for specifying the target difference in a randomised controlled trial: the Difference ELicitation in TriAls (DELTA) systematic review
(Journal article; Peer reviewed, 2014)Background Randomised controlled trials (RCTs) are widely accepted as the preferred study design for evaluating healthcare interventions. When the sample size is determined, a (target) difference is typically specified ... -
Methplotlib: Analysis of modified nucleotides from nanopore sequencing
(Journal article; Peer reviewed, 2020)Summary Modified nucleotides play a crucial role in gene expression regulation. Here, we describe methplotlib, a tool developed for the visualization of modified nucleotides detected from Oxford Nanopore Technologies ... -
Metodeutvikling og validering av en kvantitativ UHPLC-MS/MS metode for analyse av tuberkulostatika i serum
(Master thesis, 2023)Tuberkulose er en infeksjonssykdom som krever omfattende behandling med flere typer antibiotika over lengre tid (minst seks måneder). Det er risiko for terapisvikt og toksiske effekter, og terapeutisk legemiddelmonitorering ... -
Metylfenidats kliniske farmakologi
(Master thesis, 2016)Bakgrunn: Attention-deficit/hyperactivity disorder/hyperkinetisk forstyrrelse (ADHD/HF) kjennetegnes av konsentrasjonsproblemer, hyperaktivitet og økt impulsivitet. 4,3 % og 1,7 % av henholdsvis gutter og jenter i aldersgruppen ... -
MGMT Promoter Methylation Status Is Not Related to Histological or Radiological Features in IDH Wild-type Glioblastomas
(Peer reviewed; Journal article, 2020)O6-methylguanine DNA methyltransferase (MGMT) promoter methylation is an important favorable predictive marker in patients with glioblastoma (GBM). We hypothesized that MGMT status could be a surrogate marker of pretreatment ... -
Microbial communities in seawater from an Arctic and a temperate Norwegian fjord and their potentials for biodegradation of chemically dispersed oil at low seawater temperatures
(Journal article; Peer reviewed, 2018)Biodegradation of chemically dispersed oil at low temperature (0–2 °C) was compared in natural seawater from Arctic (Svalbard) and a temperate (Norway) fjords. The oil was premixed with a dispersant (Corexit 9500) and ... -
Microbial community and metagenome dynamics during biodegradation of dispersed oil reveals potential key-players in cold Norwegian seawater
(Journal article; Peer reviewed, 2018)Oil biodegradation as a weathering process has been extensively investigated over the years, especially after the Deepwater Horizon blowout. In this study, we performed microcosm experiments at 5 °C with chemically dispersed ... -
Microbiota in inflammatory bowel disease
(Doctoral theses at NTNU;2021:86, Doctoral thesis, 2021) -
Microencapsulation of small intestinal neuroendocrine neoplasm cells for tumor model studies
(Journal article; Peer reviewed, 2012)Basic cancer research is dependent on reliable in vitro and in vivo tumor models. The serotonin (5‐HT) producing small intestinal neuroendocrine tumor cell line KRJ‐1 has been used in in vitro proliferation and secretion ...