• The Mammalian Cap-Specific m<sup>6</sup>Am RNA Methyltransferase PCIF1 Regulates Transcript Levels in Mouse Tissues 

      Pandey, Radha Raman; Delfino, Elena; Homolka, David; Roithova, Adriana; Chen, Kuan-Ming; Li, Lingyun; Franco, Giulia; Vågbø, Cathrine Broberg; Taillebourg, Emmanuel; Fauvarque, Marie-Odile; Pillai, Ramesh S. (Peer reviewed; Journal article, 2020)
      The 5′ end of eukaryotic mRNAs is protected by the m7G-cap structure. The transcription start site nucleotide is ribose methylated (Nm) in many eukaryotes, whereas an adenosine at this position is further methylated at the ...
    • Management of a life-threatening intercostal artery bleeding, difficult to visualize in open surgery: a case report 

      Laugsand, Eivor Alette; Xanthoulis, Athanasios (Peer reviewed; Journal article, 2020)
      Life-threatening bleeding from an intercostal artery is a rare and challenging event. A 74-year-old patient with a right-sided pleural effusion was treated by a pigtail pleural drain. He developed a large haemothorax, ...
    • Manglende etterlevelse - også en bevisst handling 

      Bell, Hege Therese; Sletvold, Hege; Reppe, Linda Amundstuen (Journal article; Peer reviewed, 2016)
      Alle pasienter har ulike oppfatninger av sykdom og legemidler. Pasienter veier gjerne nytten av legemiddelbehandlingen mot ulemp¬ene, og dette kommuniseres ikke alltid med helsepersonell. Tro på egen mestring av legemiddelregimet ...
    • Mannose-Binding Lectin Deficiency Is Associated with Myocardial Infarction: The HUNT2 Study in Norway 

      Vengen, Inga Thorsen; Madsen, Hans O; Garred, Peter; Platou, Carl Geoffrey Parrinder; Vatten, Lars Johan; Videm, Vibeke (Journal article; Peer reviewed, 2012)
      Objectives: Mannose-binding lectin (MBL) and ficolins activate the complement cascade, which is involved in atherogenesis. Based on a pilot study, we hypothesized that functional polymorphisms in the MBL gene (MBL2) ...
    • The many functions of ESCRTs 

      Vietri, Marina; Radulovic, Maja; Stenmark, Harald (Peer reviewed; Journal article, 2019)
      Cellular membranes can form two principally different involutions, which either exclude or contain cytosol. The ‘classical’ budding reactions, such as those occurring during endocytosis or formation of exocytic vesicles, ...
    • Mapping nanoparticles in hydrogels: A comparison of preparation methods for electron microscopy 

      Muri, Harald Ian; Hoang, Linh; Hjelme, Dag Roar (Journal article; Peer reviewed, 2018)
      The distribution of noble metal nanoparticles (NMNPs) in hydrogels influences their nanoplasmonic response and signals used for biosensor purposes. By controlling the particle distribution in NMNP-nanocomposite hydrogels, ...
    • Mapping of pituitary stress-induced gene regulation connects Nrcam to negative emotions 

      Olsen, Maria Belland; Sannes, Ann-Christin; Yang, Kuan; Nielsen, Morten Birkeland; Einarsen, Ståle Valvatne; Christensen, Jan Olav; Pallesen, Ståle; Bjørås, Magnar; Gjerstad, Johannes (Peer reviewed; Journal article, 2022)
      Environmental stressors such as repeated social defeat may initiate powerful activation of subconscious parts of the brain. Here, we examine the consequences of such stress (induced by resident-intruder paradigm) on the ...
    • Mapping post - translational histone modifications and the TH2B variant in spermatogenesis 

      Holmsen, Camilla (Master thesis, 2012)
      Epigenetics has been defined by Goldberg et al. [1] as the study of heritable changes in gene expression or cellular phenotype which arises without changes in the DNA sequence. Post-translational histone modification and ...
    • Mapping the human genetic architecture of COVID-19 

      Niemi, Mari E.K.; Karjalainen, Juha; Liao, Rachel G.; Neale, Benjamin M.; Daly, Mark; Ganna, Andrea; Pathak, Gita A.; Andrews, Shea J.; Kanai, Masahiro; Veerapen, Kumar; Fernandez-Cadenas, Israel; Schulte, Eva C.; Striano, Pasquale; Afset, Jan Egil; Solligård, Erik; Damås, Jan Kristian; Risnes, Kari; Bettini, Laura Rachele; Gustad, Lise Tuset; Holter, Jan Cato; Hov, Johannes Espolin Roksund; Karlsen, Tom Hemming; Folseraas, Trine; Holten, Aleksander Rygh; Dyrhol-Riise, Anne Ma; Tonby, Kristian; Lind, Andreas; Müller, Fredrik; Dudman, Susanne Gjeruldsen; Grimsrud, Marit Mæhle; Vadla, May Sissel; Myhre, Ronny; Kildal, Anders Benjamin; Hoff, Dag Arne Lihaug; Muller, Karl Erik; Heggelund, Lars; Bergan, Jonas; Skogen, Vegard (Journal article; Peer reviewed, 2021)
      The genetic make-up of an individual contributes to the susceptibility and response to viral infection. Although environmental, clinical and social factors have a role in the chance of exposure to SARS-CoV-2 and the severity ...
    • Marine bioaktive fiskepeptider for forebygging av overvekt og mikrobiotarelaterte sykdommer i mennesker og dyr 

      Berge, Rolf Kristian; Bjørndal, Bodil; Aas, Grete Hansen; Dankel, Simon N; Remme, Jannicke; Sterten, Hallgeir; Ahlstrøm, Øystein; Hov, Johannes Espolin Roksund; Røsvik, Anne Synnøve; Hoff, Dag Arne Lihaug (Research report, 2022)
    • Markers of autoimmunity in Latent Autoimmune Diabetes in Adults (LADA) and non-diabetic adults: Impact in phenotype and genetic predisposition: Results from the Nord-Trøndelag health study 

      Sørgjerd, Elin Pettersen (Doktoravhandlinger ved NTNU, 1503-8181; 2013:113, Doctoral thesis, 2013)
      Diabetes is mainly classified: type 1 and type 2 diabetes. Type 1 diabetes is an autoimmune disease in which the body's immune system attacks and destroys the beta cells that produce insulin. Patients with type 2 diabetes ...
    • Markers of endothelial glycocalyx dysfunction in Clarkson disease 

      Xie, Zhihui; Børset, Magne; Sveen, Kjell; Bøe, Ole Wilhelm; Chan, Eunice C.; Lack, Justin B.; Hornick, Katherine M.; Verlicchi, Franco; Eisch, A. Robin; Melchio, Remo; Dudek, Arkadiusz Z.; Druey, Kirk M. (Peer reviewed; Journal article, 2022)
      Background Clarkson disease (monoclonal gammopathy-associated idiopathic systemic capillary leak syndrome, ISCLS) is a rare idiopathic condition marked by transient, relapsing-remitting episodes of systemic microvascular ...
    • Markers of Kidney Tubular Secretion and Risk of Adverse Events in SPRINT Participants with CKD 

      Bullen, Alexander L.; Ascher, Simon B.; Scherzer, Rebecca; Garimella, Pranav S.; Katz, Ronit; Hallan, Stein; Cheung, Alfred K.; Raphael, Kalani L.; Estrella, Michelle M.; Jotwani, Vasantha K.; Malhotra, Rakesh; Seegmiller, Jesse C.; Shlipak, Michael G.; Ix, Joachim H. (Peer reviewed; Journal article, 2022)
      Significance Statement SPRINT demonstrated in individuals with hypertension and high cardiovascular disease (CVD) risk that intensive BP lowering was associated with decreased risk of CVD events and all-cause mortality. ...
    • Markers of placental insufficiency: etiology and the risk of cerebral palsy:Population based studies of preeclampsia, low birth weight, and abnormal placental weight 

      Strand, Kristin Melheim (Doctoral thesis at NTNU;2015:172, Doctoral thesis, 2015)
      Placental insufficiency may be defined as a placenta not able to perform its central tasks; namely, delivery of sufficient oxygen and nutrients to the developing fetus. In this thesis, preeclampsia, fetal growth restriction ...
    • Mass spectrometry for the evaluation of monoclonal proteins in multiple myeloma and related disorders: an International Myeloma Working Group Mass Spectrometry Committee Report 

      Murray, David L.; Puig, Noemi; Kristinsson, Sigurður Y.; Usmani, Saad; Dispenzieri, Angela; Bianchi, Giada; Kumar, Shaji; Chng, Wee Joo; Hajek, Roman; Paiva, Bruno; Waage, Anders; Rajkumar, S. Vincent; Durie, Brian (Peer reviewed; Journal article, 2021)
      Plasma cell disorders (PCDs) are identified in the clinical lab by detecting the monoclonal immunoglobulin (M-protein) which they produce. Traditionally, serum protein electrophoresis methods have been utilized to detect ...
    • Massive parallel amplicon sequencing of the mismatch repair genes MSH2, MSH6, MLH1 and PMS2. Implementation of hereditary and non-hereditary subtypes of colorectal cancer 

      Neckmann, Ulrike (Master thesis, 2013)
      &nbsp;Colorectal cancer is the one of the most frequent malignancies and accounts for approximately 3500 new cases each year in Norway. Colorectal cancer is a heterogeneous disorder and can be divided into three main groups: ...
    • Maternal alcohol and drug use during pregnancy affects the motor behaviour and general movements of infants aged 3–4 months 

      Fjørtoft, Toril Larsson; Brandal, Merethe; Brubakk, Ann-Mari; Adde, Lars; Ustad, T.; Vågen, Randi Tynes; Evensen, Kari Anne Indredavik (Peer reviewed; Journal article, 2020)
      Background Exposure of alcohol and/or other addictive drugs in pregnancy is a documented risk factor for later neurological impairment. Aims The aim of the study was to determine whether infants suffering from prenatal ...
    • Maternal exposure to childhood maltreatment and mental and behavioral disorders in children 

      Airikka, Aino; Lahti-Pulkkinen, Marius; Tuovinen, Soile; Heinonen, Kati; Lahti, Jari; Girchenko, Polina; Lähdepuro, Anna; Pyhälä, Riikka; Czamara, Darina; Villa, Pia; Laivuori, Hannele; Kajantie, Eero Olavi; Binder, Elisabeth B.; Räikkönen, Katri (Peer reviewed; Journal article, 2022)
      Exposure to maltreatment in childhood is associated with lifelong risk of mental and behavioral disorders. Whether the effects extend to the next generation remains unclear. We examined whether maternal exposure to childhood ...
    • Maternal haemoglobin levels in pregnancy and child DNA methylation: a study in the pregnancy and childhood epigenetics consortium 

      Ronkainen, Justiina; Heiskala, Anni; Vehmeijer, Florianne O.; Lowry, Estelle; Caramaschi, Doretta; Estrada Gutierrez, Guadalupe; Heiss, Jonathan A.; Hummel, Nadine; Keikkala, Elina; Kvist, Tuomas; Kupsco, Allison; Melton, Phillip E.; Pesce, Giancarlo; Soomro, Munawar Hussain; Vives-Usano, Marta; Baïz, Nour; Binder, Elisabeth B.; Czamara, Darina; Guxens, Mònica; Mustaniemi, Sanna; London, Stephanie J.; Rauschert, Sebastian; Vääräsmäki, Marja; Vrijheid, Martine; Ziegler, Anette-G.; Annesi-Maesano, Isabella; Bustamante, Mariona; Huang, Rae-Chi; Hummel, Sandra; Just, Allan C.; Kajantie, Eero Olavi; Lahti, Jari; Lawlor, Debbie A.; Räikkönen, Katri; Jarvelin, Marjo-Riitta; Felix, Janine F.; Sebert, Sylvain (Peer reviewed; Journal article, 2021)
      Altered maternal haemoglobin levels during pregnancy are associated with pre-clinical and clinical conditions affecting the fetus. Evidence from animal models suggests that these associations may be partially explained by ...
    • Maternal mental health and adverse birth outcomes 

      Voit, Falk A.C.; Kajantie, Eero Olavi; Lemola, Sakari; Räikkönen, Katri; Wolke, Dieter; Schnitzlein, Daniel D. (Peer reviewed; Journal article, 2022)
      Recent research in economics emphasizes the role of in utero conditions for the health endowment at birth and in early childhood and for social as well as economic outcomes in later life. This paper analyzes the relation ...