Blar i Institutt for klinisk og molekylær medisin på tittel
Viser treff 1707-1726 av 3426
-
Interleukin-6 receptor inhibition with tocilizumab induces a selective and substantial increase in plasma IP-10 and MIP-1β in non-ST-elevation myocardial infarction
(Journal article; Peer reviewed, 2018)Aim To evaluate the effect of interleukin-6 inhibition with tocilizumab on the cytokine network in patients with acute non-ST-elevation myocardial infarction (NSTEMI). Methods 117 patients with acute NSTEMI were randomised ... -
Intermittent energy restriction ameliorates adipose tissue-associated inflammation in adults with obesity: A randomised controlled trial
(Peer reviewed; Journal article, 2022)Background & aims Although intermittent energy restriction (IER) seems to be as effective as continuous energy restriction (CER) for weight loss, there is still a need to determine the putative effect of this strategy ... -
Interobserver agreement and prognostic impact for MRI–based 2018 FIGO staging parameters in uterine cervical cancer
(Peer reviewed; Journal article, 2022)Objectives To evaluate the interobserver agreement for MRI–based 2018 International Federation of Gynecology and Obstetrics (FIGO) staging parameters in patients with cervical cancer and assess the prognostic value of ... -
Interobserver Reliability for Identifying Specific Patterns of Placental Injury as Defined by the Amsterdam Classification
(Peer reviewed; Journal article, 2021)Context.—: Placental pathology is an essential tool for understanding neonatal illness. The recent Amsterdam international consensus has standardized criteria and terminology, providing harmonized data for research and ... -
Interplay of Single-Stranded RNA Viruses with Autophagy: Intracellular Mechanisms and Functional Impact
(Doctoral thesis at NTNU;2015:76, Doctoral thesis, 2015)Samspillet mellom enkelt-trådet RNA virus og autofagi: intracellulære mekanismer og funksjonell betydning: Virus er i stand til å infisere alle levende organismer fra planter til mennesker. De er fullstendig avhengig ... -
InterPregGen: Genetic studies of pre-eclampsia in three continents
(Journal article; Peer reviewed, 2014)Pre-eclampsia is a major cause of maternal and fetal mortality in pregnancy. The identification of genetic variants which predispose to pre-eclampsia demands large DNA collections from affected mothers and babies and ... -
The Intersection of COVID-19 and Metabolic-Associated Fatty Liver Disease: An Overview of the Current Evidence
(Journal article; Peer reviewed, 2023) -
Interventions and symptom relief in hospital palliative cancer care: results from a prospective longitudinal study
(Journal article; Peer reviewed, 2021)Purpose To study the use of interventions and symptom relief for adult patients with incurable cancer admitted to an acute palliative care unit providing integrated oncology and palliative care services. Methods All ... -
Intestinal Epithelial Cell-Intrinsic Deletion of Setd7 Identifies Role for Developmental Pathways in Immunity to Helminth Infection
(Journal article; Peer reviewed, 2016)The intestine is a common site for a variety of pathogenic infections. Helminth infections continue to be major causes of disease worldwide, and are a significant burden on health care systems. Lysine methyltransferases ... -
Intestinal epithelial cells express immunomodulatory ISG15 during active ulcerative colitis and Crohn's disease
(Peer reviewed; Journal article, 2020)Background and Aims Intestinal epithelial cells [IECs] secrete cytokines that recruit immune cells to the mucosa and regulate immune responses that drive inflammation in inflammatory bowel disease [IBD]. However, experiments ... -
Intestinal inflammatory profile shows increase in a diversity of biomarkers in irritable bowel syndrome
(Peer reviewed; Journal article, 2020)Background: It has been proposed that irritable bowel syndrome (IBS) is a low-grade mucosal inflammatory disease. Objective: To characterize the intestinal inflammatory profile in IBS patients with or without fructose ... -
Intestinal injury and recovery after ishemia - An experimental study on restitution of the surface epithelium, intestinal permeability, and release of biomarkers from the mucosa
(Doktoravhandlinger ved NTNU, 1503-8181; 2007:212, Doctoral thesis, 2007) -
Intestinal-epithelial LSD1 controls goblet cell maturation and effector responses required for gut immunity to bacterial and helminth infection
(Peer reviewed; Journal article, 2021)Infectious and inflammatory diseases in the intestine remain a serious threat for patients world-wide. Reprogramming of the intestinal epithelium towards a protective effector state is important to manage inflammation and ... -
Intracellular and Subnuclear Trafficking of Activation-Induced cytidine Deaminase (AID)
(Doktoravhandlinger ved NTNU, 1503-8181; 2013:136, Doctoral thesis, 2013) -
Intracellular Complement Component 3 Attenuated Ischemia-Reperfusion Injury in the Isolated Buffer-Perfused Mouse Heart and Is Associated With Improved Metabolic Homeostasis
(Peer reviewed; Journal article, 2022)The innate immune system is rapidly activated during myocardial infarction and blockade of extracellular complement system reduces infarct size. Intracellular complement, however, appears to be closely linked to metabolic ... -
Intracellular glutathione determines bortezomib cytotoxicity in multiple myeloma cells
(Journal article; Peer reviewed, 2016)Multiple myeloma (myeloma in short) is an incurable cancer of antibody-producing plasma cells that comprise 13% of all hematological malignancies. The proteasome inhibitor bortezomib has improved treatment significantly, ... -
Intracellular growth of Mycobacterium avium subspecies and global transcriptional responses in human macrophages after infection
(Journal article; Peer reviewed, 2014)Background Mycobacterium avium subsp. avium (Maa) and M. avium subsp. hominissuis (Mah) are environmental mycobacteria and significant opportunistic pathogens. Mycobacterium avium infections in humans and pigs are mainly ... -
Intracellular IL-32 regulates mitochondrial metabolism, proliferation, and differentiation of malignant plasma cells
(Journal article; Peer reviewed, 2021)Interleukin-32 (IL-32) is a nonclassical cytokine expressed in cancers, inflammatory diseases, and infections. Its expression is regulated by two different oxygen sensing systems; HIF1α and cysteamine dioxygenase (ADO), ... -
Intracellular signaling mechanisms in the innate immune response to viral infections
(Doktoravhandlinger ved NTNU, 1503-8181; 2009:120, Doctoral thesis, 2009) -
Intracellular Survival and Immune System Activation Following Viral Scavenging in Murine Liver Sinusoidal Endothelial Cells
(Master thesis, 2021)Lever sinusformede endotelceller (LSEC) er profesjonelle endocytter med en ekstraordinær evne til å fjerne forskjellige avfallsmaterialer som kan være tilstede i blodet. LSECene blir i økende grad anerkjent som sentrale ...