Browsing Institutt for klinisk og molekylær medisin by Title
Now showing items 1362-1381 of 2008
-
Pharmacokinetics of Perfluorobutane after Intra-venous Bolus Injection of Sonazoid in Healthy Chinese Volunteers.
(Journal article; Peer reviewed, 2017)Sonazoid is an ultrasound contrast agent based on microbubbles (MB) containing perfluorobutane (PFB) gas. Sonazoid is approved in Japan, Korea and Norway for contrast-enhanced ultrasonography of focal liver lesions and ... -
Pharmacokinetics, drug interactions and adherence to treatment with antipsychotics: Studies in a naturalistic setting
(Doktoravhandlinger ved NTNU, 1503-8181; 2010:7, Doctoral thesis, 2010)Studien tar utgangspunkt i resultater fra serumkonsentrasjonsmålinger i prøver analysert ved Avdeling for klinisk farmakologi ved St. Olavs Hospital i Trondheim. Formålet med studien var å undersøke klinisk relevante ... -
PhD budget regulations at NTNU
(Research report, 2016)During 2015-2016, DION, the interest organization for doctoral candidates and postdoctoral researchers at NTNU, conducted an analysis of the various PhD budget (aka driftsmidler or working capital) related definitions, ... -
PhD duty work regulations at NTNU
(Research report, 2016)During 2015-2016, DION, the interest organization for doctoral candidates and postdoctoral researchers at NTNU, conducted an analysis of the various PhD duty work (aka pliktarbeid, aka teaching load) related definitions, ... -
PhD working conditions at NTNU with a special focus on PhD candidates with kids
(Research report, 2017)During 2016-2017, DION conducted an analysis of the PhD working conditions at NTNU, with special focus on PhDs with children. All NTNU PhD candidates were invited to respond to a survey regarding working conditions and ... -
Phenotypic stability of early passage stromal cell lines isolated from prostatic adenocarcinoma
(Master thesis, 2017)Introduction: The thorough characterization of markers and phenotypic stability in early passage cell lines is necessary for the proper interpretation of data generated by their use. In our research group, 20 early passage ... -
Phenylalanine Hydroxylase RNAi Knockdown Negatively Affects Larval Development, Molting and Swimming Performance of Salmon Lice
(Peer reviewed; Journal article, 2020)Phenylalanine hydroxylase (PAH) is a crucial enzyme involved in tyrosine biosynthesis, having roles in neurological and physiological processes. The purpose of PAH has received little attention in crustaceans despite ... -
Phosphatase of regenerating liver 3 (PRL-3) is overexpressed in human prostate cancer tissue and promotes growth and migration
(Journal article; Peer reviewed, 2016)Background: PRL-3 is a phosphatase implicated in oncogenesis in multiple cancers. In some cancers, notably carcinomas, PRL-3 is also associated with inferior prognosis and increased metastatic potential. In this study we ... -
Phosphatase of regenerating liver-3 (PRL-3) is overexpressed in classical Hodgkin lymphoma and promotes survival and migration
(Journal article; Peer reviewed, 2018)Background Phosphatase of regenerating liver-3 (PRL-3) is implicated in oncogenesis of hematological and solid cancers. PRL-3 expression increases metastatic potential, invasiveness and is associated with poor prognosis. ... -
Phosphatase of regenerating liver-3 as a target for treatment of B cell malignancies
(Doctoral theses at NTNU;2018:241, Doctoral thesis, 2018)PRL-3 som et angrepsmål i behandlingen av B-cellekreft Akutt lymfatisk leukemi (ALL), Hodgkin lymfom (HL) og myelomatose er kreftsykdommer som oppstår fra B-lymfocytter. Disse cellene er en del av kroppens immunforsvar. ... -
Phosphatase of regenerating liver-3 is expressed in acute lymphoblastic leukemia and mediates leukemic cell adhesion, migration and drug resistance
(Journal article; Peer reviewed, 2017)Phosphatase of regenerating liver-3 (PRL-3/PTP4A3) is upregulated in multiple cancers, including BCR-ABL1- and ETV6-RUNX-positive acute lymphoblastic leukemia (ALL). With this study, we aim to characterize the biological ... -
Photochemical internalization of peptide antigens provides a novel strategy to realize therapeutic cancer vaccination
(Journal article; Peer reviewed, 2018)Effective priming and activation of tumor-specific CD8+ cytotoxic T lymphocytes (CTLs) is crucial for realizing the potential of therapeutic cancer vaccination. This requires cytosolic antigens that feed into the MHC class ... -
Phylogeographical pattern of Francisella tularensis in a nationwide outbreak of tularaemia in Norway, 2011
(Journal article; Peer reviewed, 2015)In 2011, a nationwide outbreak of tularaemia occurred in Norway with 180 recorded cases. It was associated with the largest peak in lemming density seen in 40 years. Francisella tularensis was isolated from 18 patients. ... -
Physical activity and exercise interventions in cancer patients
(Dissertations at the Faculty of Medicine, 0805-7680; 279, Doctoral thesis, 2006) -
Physical activity and health in a general population and in cancer survivors: – Methodological, observational and clinical aspects
(Doktoravhandlinger ved NTNU, 1503-8181; 2012:91, Doctoral thesis, 2012)Helserelatert livskvalitet, ofte uttrykt som selvrapportert fysisk og psykisk helse, er viktig for å fungere i dagliglivet og er ofte et mål for ulike helserettede tiltak. Fysisk aktivitet spiller en viktig rolle for ... -
Physical exercise during adjuvant chemotherapy for colorectal cancer - a non-randomized feasibility study
(Peer reviewed; Journal article, 2020)Background Colorectal cancer (CRC) is the third most common cancer worldwide, and a large proportion of the patients receive adjuvant oxaliplatin-based chemotherapy. Most of these experience chemotherapy-induced peripheral ... -
Physicians’ Recognition and Management of Kidney Disease: A Randomized Vignette Study Evaluating the Impact of the KDIGO 2012 CKD Classification System
(Peer reviewed; Journal article, 2020)Rationale & Objective The Kidney Disease Outcome Quality Initiative (KDOQI) and Kidney Disease: Improving Global Outcomes (KDIGO) chronic kidney disease (CKD) classification systems published in 2002 and 2012, respectively, ... -
Physiologically-based pharmacokinetic models for CYP1A2 drug-drug interaction prediction: A modeling network of fluvoxamine, theophylline, caffeine, rifampicin, and midazolam
(Journal article; Peer reviewed, 2019)This study provides whole‐body physiologically‐based pharmacokinetic models of the strong index cytochrome P450 (CYP)1A2 inhibitor and moderate CYP3A4 inhibitor fluvoxamine and of the sensitive CYP1A2 substrate theophylline. ... -
Physiotherapy in infants born preterm: Measurement tools for assessing motor function in infancy and a randomised controlled trial of early intervention to optimise motor function
(Doctoral theses at NTNU;2016:353, Doctoral thesis, 2016)Fysioterapi til for tidlig fødte barn. Måleredskap for vurdering av motorisk funksjon i spedbarnsalderen og en randomisert kontrollert studie av tidlig intervensjon for å optimalisere motorisk funksjon Barn som ... -
Pituitary adenoma and non-acute headache: is there an association, and does treatment help?
(Journal article; Peer reviewed, 2016)Objective Headache is a controversial indication for treatment of pituitary adenoma. We studied the possible relationship between pituitary adenomas and headache as well as the symptomatic effects of treatment. Met ...