• General movement optimality score and general movements trajectories following early parent-administrated physiotherapy in the neonatal intensive care unit 

      Ustad, Tordis; Fjørtoft, Toril Larsson; Øberg, Gunn Kristin (Peer reviewed; Journal article, 2021)
      Background The Prechtl General Movement Assessment (GMA) is a reliable tool for the functional assessment of the young nervous system. It is based on a global assessment of the quality of infants' movements. In addition, ...
    • General principles for the risk assessment of “other substances” in food supplements and energy drinks. Report of the Panel on Food Additives, Flavourings, Processing Aids, Materials in Contact with Food and Cosmetics and the Panel on Nutrition, Dietetic Products, Novel Food and Allergy of the Norwegian Scientific Committee for Food Safety 

      Bruzell, Ellen Merete; Granum, Berit; Hetland, Ragna Bogen; Husøy, Trine; Rohloff, Jens; Wicklund, Trude; Frøyland, Livar; Haugen, Margaretha; Holvik, Kristin; Løvik, Martinus; Strand, Tor A; Tell, Grethe S.; Vaktskjold, Arild; Iversen, Per Ole; Steffensen, Inger-Lise (VKM Report;, Research report, 2015)
    • Generation and Functional In Vitro Analysis of Semliki Forest Virus Vectors Encoding TNF-α and IFN-γ 

      Kurena, Baiba; Müller, Elisabeth; Christopoulos, Panagiotis; Johnsen, Ingvild Bjellmo; Stankovic, Branislava; Øynebråten, Inger; Corthay, Alexandre; Zajakina, Anna (Journal article; Peer reviewed, 2017)
      Cytokine gene delivery by viral vectors is a promising novel strategy for cancer immunotherapy. Semliki Forest virus (SFV) has many advantages as a delivery vector, including the ability to (i) induce p53-independent killing ...
    • Generation of a Mouse Model Lacking the Non-Homologous End-Joining Factor Mri/Cyren 

      Castaneda Zegarra, Sergio Miguel; Huse, Camilla; Røsand, Øystein; Sarno, Antonio; Xing, Mengtan; Zhang, Qindong; Alirezaylavasani, Amin; Werner, Julia; Ji, Ping; Liabakk, Nina-Beate; Wang, Wei; Bjørås, Magnar; Oksenych, Valentyn (Journal article; Peer reviewed, 2019)
      Classical non-homologous end joining (NHEJ) is a molecular pathway that detects, processes, and ligates DNA double-strand breaks (DSBs) throughout the cell cycle. Mutations in several NHEJ genes result in neurological ...
    • The genes controlling normal function of citrate and spermine secretion are lost in aggressive prostate cancer and prostate model systems 

      Rye, Morten Beck; Krossa, Sebastian; Hall, Martina; van Mourik, Casper; Bathen, Tone Frost; Drabløs, Finn; Tessem, May-Britt; Bertilsson, Helena (Peer reviewed; Journal article, 2022)
      High secretion of the metabolites citrate and spermine is a unique hallmark for normal prostate epithelial cells, and is reduced in aggressive prostate cancer. However, the identity of the genes controlling this biological ...
    • Genetic Aberrationsin Myeloma Cells 

      Våtsveen, Thea Kristin (Doktoravhandlinger ved NTNU, 1503-8181; 2009:83, Doctoral thesis, 2009)
      Genetiske avvik i myelomceller Myelomatose (beinmargskreft) er kreft i plasmacellene i beinmargen. Det er den nest vanligste hematologiske kreftformen og rammer ca 300 personer i Norge hvert år. Kun 15% av pasientene er ...
    • Genetic and molecular functional characterization of variants within TNFSF13B, a positional candidate preeclampsia susceptibility gene on 13q 

      Fenstad, Mona Høysæter; Johnson, Matthew; Roten, Linda Tømmerdal; Aas, Per Arne; Forsmo, Siri; Klepper, Kjetil; East, Christine; Abraham, Lawrence j.; Blangero, John; Brennecke, Shaun P.; Austgulen, Rigmor; Moses, Eric K (Journal article; Peer reviewed, 2010)
      Background: Preeclampsia is a serious pregnancy complication, demonstrating a complex pattern of inheritance. The elucidation of genetic liability to preeclampsia remains a major challenge in obstetric medicine. We have ...
    • Genetic and Non-genetic Factors Associated WithConstipation in Cancer Patients Receiving Opioids 

      Laugsand, Eivor Alette; Skorpen, Frank; Kaasa, Stein; Sabatowski, Rainer; Strasser, Florian; Fayers, Peter; Klepstad, Pål (Journal article; Peer reviewed, 2015)
      Objectives: To examine whether the inter-individual variation in constipation among patients receiving opioids for cancer pain is associated with genetic or non-genetic factors. Methods: Cancer patients receiving ...
    • Genetic biomarkers in multiple myeloma 

      Rustad, Even Holth (Doctoral theses at NTNU;2019: 223, Doctoral thesis, 2019)
      Multiple myeloma is a cancer of plasma cells in the bone marrow that accounts for 2 % of cancer cases globally. Improved understanding of the molecular basis of this disease has resulted in new treatment options and prolonged ...
    • Genetic diversity and drug resistance pattern of Mycobacterium tuberculosis strains isolated from pulmonary tuberculosis patients in the Benishangul Gumuz region and its surroundings, Northwest Ethiopia 

      Lobie, Tekle Airgecho; Woldeamanuel, Yimtubezinash; Asrat, Daniel; Beyene, Demissew Balcha; Bjørås, Magnar; Aseffa, Abraham (Peer reviewed; Journal article, 2020)
      Introduction Tuberculosis (TB) remains a major global public health problem and is the leading cause of death from a single bacterium, Mycobacterium tuberculosis (MTB) complex. The emergence and spread of drug-resistant ...
    • Genetic diversity of rotavirus strains circulating in Norway before and after the introduction of rotavirus vaccination in children 

      Gibory, Moustafa; Bruun, Tone; Flem, Elmira; Dembinski, Jennifer Lynn; Haltbakk, Ildri; Størdal, Ketil; Nordbø, Svein Arne; Jakobsen, Kirsti; Haarr, Elisebet; Leegaard, Truls Michael; Dudman, Susanne Gjeruldsen (Peer reviewed; Journal article, 2021)
      Globally, rotavirus (RV) is the leading cause of acute gastroenteritis (AGE) in young children under 5 years of age. Implementation of RV vaccination is expected to result in fewer cases of RV in the target population, but ...
    • Genetic Engineering for Revealing Underlying Mechanisms of Inflammatory Bowel Diseases 

      Roseth, Ingrid Aass (Master thesis, 2020)
      Inflammatorisk tarmsykdom, også kalt IBD, er en samlebetegnelse på kronisk betennelse i tarmen. IBD består i hovedsak av ulcerøs kolitt og Crohns sykdom. De underliggende årsakene er i stor grad ukjent, men både genetikk, ...
    • Genetic interaction between accessory non-homologous end joining factors in B and T lymphocyte development 

      Alirezaylavasani, Amin (Master thesis, 2020)
      DNA dobbeltstrengsbrudd (DSB) induseres av eksogene og endogene faktorer. Ikke-homolog endeforbindelse (NHEJ) -vei er et reparasjonssystem som omhandler DSB-er over hele cellesyklusen. NHEJ er nødvendig for V (D) J-rekombinasjon ...
    • Genetic Interaction Between DNA Repair Factors in Lymphocyte Development 

      Huse, Camilla (Master thesis, 2019)
      Dobbeltråd-brudd (DSB) på DNA-tråden er den mest cytotoksiske skaden i cellene våre. I løpet av utviklingen av B- og T-celler introduseres DSBs med vilje i løpet av V(D)J rekombinasjonen, og repareres av den ikke-homologe ...
    • Genetic interaction between DNA repair factors PAXX, XLF, XRCC4 and DNA-PKcs in human cells 

      Xing, Mengtan; Oksenych, Valentyn (Journal article; Peer reviewed, 2019)
      DNA double‐strand breaks (DSBs) are highly cytotoxic lesions, and unrepaired or misrepaired DSBs can lead to various human diseases, including immunodeficiency, neurological abnormalities, growth retardation, and cancer. ...
    • Genetic interaction between the non-homologous end joining factors in mice and humans 

      Xing, Mengtan (Doctoral theses at NTNU;2019:117, Doctoral thesis, 2019)
    • Genetic interaction between the non‐homologous end joining factors during B and T lymphocyte development: in vivo mouse models 

      Castaneda Zegarra, Sergio Miguel; Fernandez Berrocal, Marion Silvana; Tkachev, Max; Yao, Rouan; Esnardo Upfold, Nikki Lyn; Oksenych, Valentyn (Peer reviewed; Journal article, 2020)
      Non-homologous end joining (NHEJ) is the main DNA repair mechanism for the repair of double-strand breaks (DSBs) throughout the course of the cell cycle. DSBs are generated in developing B and T lymphocytes during V(D)J ...
    • Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies 

      Gorski, Mathias; Rasheed, Humaira; Teumer, Alexander; Thomas, Laurent; Graham, Sarah E.; Sveinbjornsson, Gardar; Winkler, Thomas W.; Günther, Felix; Stark, Klaus J.; Chai, Jin-Fang; Tayo, Bamidele O.; Wuttke, Matthias; Li, Yong; Tin, Adrienne; Ahluwalia, Tarunveer S.; Ärnlöv, Johan; Åsvold, Bjørn Olav; Bakker, Stephan J.L.; Banas, Bernhard; Bansal, Nisha; Biggs, Mary L.; Biino, Ginevra; Böhnke, Michael; Boerwinkle, Eric; Bottinger, Erwin P.; Brenner, Hermann; Brumpton, Ben Michael; Carroll, Robert J.; Chaker, Layal; Chalmers, John; Chee, Miao-Li; Chee, Miao-Ling; Cheng, Ching-Yu; Chu, Audrey Y.; Ciullo, Marina; Cocca, Massimiliano; Cook, James P.; Coresh, Josef; Cusi, Daniele; de Borst, Martin H.; Degenhardt, Frauke; Eckardt, Kai-Uwe; Endlich, Karlhans; Evans, Michele K.; Feitosa, Mary F.; Franke, Andre; Freitag-Wolf, Sandra; Fuchsberger, Christian; Gampawar, Piyush; Gansevoort, Ron T.; Ghanbari, Mohsen; Ghasemi, Sahar; Giedraitis, Vilmantas; Gieger, Christian; Gudbjartsson, Daniel F.; Hallan, Stein; Hamet, Pavel; Hishida, Asahi; Ho, Kevin; Hofer, Edith; Holleczek, Bernd; Holm, Hilma; Hoppmann, Anselm; Horn, Katrin; Hutri-Kähönen, Nina; Hveem, Kristian; Hwang, Shih-Jen; Ikram, M. Arfan; Josyula, Navya Shilpa; Jung, Bettina; Kähönen, Mika; Karabegović, Irma; Khor, Chiea-Chuen; Koenig, Wolfgang; Kramer, Holly; Krämer, Bernhard K.; Kühnel, Brigitte; Kuusisto, Johanna; Laakso, Markku; Lange, Leslie A.; Lehtimäki, Terho; Li, Man; Lieb, Wolfgang; Lind, Lars; Lindgren, Cecilia M.; Loos, Ruth J.F.; Lukas, Mary Ann; Lyytikäinen, Leo-Pekka; Mahajan, Anubha; Matias-Garcia, Pamela R.; Meisinger, Christa; Meitinger, Thomas; Melander, Olle; Milaneschi, Yuri; Mishra, Pashupati P.; Mononen, Nina; Morris, Andrew P.; Mychaleckyj, Josyf C.; Nadkarni, Girish N.; Naito, Mariko; Nakatochi, Masahiro; Nalls, Mike A.; Nauck, Matthias; Nikus, Kjell; Ning, Boting; Nolte, Ilja M.; Nutile, Teresa; O'Donoghue, Michelle L.; O'Connell, Jeffrey; Olafsson, Isleifur; Orho-Melander, Marju; Parsa, Afshin; Pendergrass, Sarah A.; Penninx, Brenda W.J.H.; Pirastu, Mario; Preuss, Michael H.; Psaty, Bruce M.; Raffield, Laura M.; Raitakari, Olli T.; Rheinberger, Myriam; Rice, Kenneth M.; Rizzi, Federica; Rosenkranz, Alexander R.; Rossing, Peter; Rotter, Jerome I.; Ruggiero, Daniela; Ryan, Kathleen A.; Sabanayagam, Charumathi; Salvi, Erika; Schmidt, Helena; Schmidt, Reinhold; Scholz, Markus; Schöttker, Ben; Schulz, Christina-Alexandra; Sedaghat, Sanaz; Shaffer, Christian M.; Sieber, Karsten B.; Sim, Xueling; Sims, Mario; Snieder, Harold; Stanzick, Kira J.; Thorsteinsdottir, Unnur; Stocker, Hannah; Strauch, Konstantin; Stringham, Heather M.; Sulem, Patrick; Szymczak, Silke; Taylor, Kent D.; Thio, Chris H.L.; Tremblay, Johanne; Vaccargiu, Simona; van der Harst, Pim; van der Most, Peter J.; Verweij, Niek; Völker, Uwe; Wakai, Kenji; Waldenberger, Melanie; Wallentin, Lars; Wallner, Stefan; Wang, Judy; Waterworth, Dawn M.; White, Harvey D.; Willer, Cristen J.; Wong, Tien-Yin; Woodward, Mark; Yang, Qiong; Yerges-Armstrong, Laura M.; Zimmermann, Martina; Zonderman, Alan B.; Bergler, Tobias; Stefansson, Kari; Böger, Carsten A.; Pattaro, Cristian; Köttgen, Anna; Kronenberg, Florian; Heid, Iris M. (Peer reviewed; Journal article, 2022)
      Estimated glomerular filtration rate (eGFR) reflects kidney function. Progressive eGFR-decline can lead to kidney failure, necessitating dialysis or transplantation. Hundreds of loci from genome-wide association studies ...
    • Genetic predisposition for development of preeclampsia: Candidate gene studies in the HUNT(Nord-Trøndelag Health Study) population 

      Roten, Linda Tømmerdal (Doktoravhandlinger ved NTNU, 1503-8181; 2009:157, Doctoral thesis, 2009)
      Preeclampsia is a major cause of maternal morbidity and mortality in the western world, and approximately 63,000 women dye yearly of the disease worldwide. This disorder is characterized by increased maternal blood pressure ...
    • Genetic predisposition to hypertension is associated with preeclampsia in European and Central Asian women 

      Steinthorsdottir, Valgerdur; McGinnis, Ralph; Williams, Nicholas O.; Stefánsdóttir, Lilja; Thorleifsson, Gudmar; Shooter, Scott; Fadista, João; Sigurdsson, Jon K.; Auro, Kirsi; Berezina, Galina; Borges, Maria-Carolina; Bumpstead, Suzannah; Bybjerg-Grauholm, Jonas; Colgiu, Irina; Dolby, Vivien A.; Dudbridge, Frank; Engel, Stephanie M.; Franklin, Christopher S.; Frigge, Michael L; Frisbaek, Yr; Geirsson, Reynir T.; Geller, Frank; Gretarsdottir, Solveig; Gudbjartsson, Daniel F.; Harmon, Quaker; Hougaard, David Michael; Hegay, Tatyana; Helgadottir, Anna; Hjartardóttir, Sigrún; Jääskeläinen, Tiina; Johannsdottir, Hrefna; Jonsdottir, Ingileif; Juliusdottir, Thorhildur; Kalsheker, Noor; Kasimov, Abdumadjit; Kemp, John P.; Kivinen, Katja; Klungsøyr, Kari; Lee, Wai K; Melbye, Mads; Miedzybrodska, Zosia; Moffett, Ashley; Najmutdinova, Dilbar; Nishanova, Firuza; Olafsdottir, Thorunn; Perola, Markus; Pipkin, Fiona Broughton; Poston, Lucilla; Prescott, Gordon; Saevarsdottir, Saedis; Salimbayeva, Damilya; Scaife, Paula Juliet; Skotte, Line; Staines-Urias, Eleonora; Stefansson, Olafur A.; Sørensen, Karina Meden; Thomsen, Liv Cecilie Vestrheim; Tragante, Vinicius; Trogstad, Lill; Simpson, Nigel A.B.; Aripova, Tamara; Casas, Juan P; Dominiczak, Anna F; Walker, James J.; Thorsteinsdottir, Unnur; Iversen, Ann-Charlotte; Feenstra, Bjarke; Lawlor, Deborah A.; Boyd, Heather Allison; Magnus, Per; Laivuori, Hannele; Zakhidova, Nodira; Syvatova, Gulnara; Stefansson, Kari; Morgan, Linda (Peer reviewed; Journal article, 2020)
      Preeclampsia is a serious complication of pregnancy, affecting both maternal and fetal health. In genome-wide association meta-analysis of European and Central Asian mothers, we identify sequence variants that associate ...