Blar i Institutt for klinisk og molekylær medisin på tittel
Viser treff 1176-1195 av 3426
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Fecal neutrophil gelatinase-associated lipocalin as a biomarker for inflammatory bowel disease
(Journal article; Peer reviewed, 2017)Background and Aim Accurate, noninvasive biomarkers are needed to diagnose and monitor inflammatory bowel disease (IBD). Neutrophil gelatinase-associated lipocalin (NGAL), also known as lipocalin 2, is expressed in inflamed ... -
Feeding Behavior and Body Weight Development:: Lessons from Rats
(Doktoravhandlinger ved NTNU, 1503-8181; 2008:251, Doctoral thesis, 2008)Background and aim Strains of rats in use today are derived almost exclusively from the Norway rat. Common outbred stocks are Wistar, Long-Evans and Sprague-Dawley, which are believed to better mimic the diverse genetics ... -
Felles referanseområder for antiepileptika
(Journal article; Peer reviewed, 2017)Antiepileptika er grunnsteinen i behandlingen av epilepsi og brukes også ved en rekke andre indikasjoner. Serumkonsentrasjonsmåling av antiepileptika har hatt lang tradisjon som hjelpemiddel i behandling av epilepsi i ... -
Fetal and perinatal implications of anomalies in the gastrointestinal tract and the abdominal wall
(Doktoravhandlinger ved NTNU, 1503-8181; 2007:113, Doctoral thesis, 2007)Studien tar for seg tilstandene gastroschise og omfalocele, som er forskjellige former for bukveggsdefekter samt utviklingsavvik som gir forsnevringer på ulike nivå i fordøyelseskanalen: spiserør (øsofagusobstruksjon), ... -
Fetal growth and birth anthropometrics in metformin exposed offspring born to mothers with PCOS
(Journal article; Peer reviewed, 2017)Context Metformin is used in an attempt to reduce pregnancy complications associated with polycystic ovary syndrome (PCOS). Little is known about the effect of metformin on fetal development and growth. Objectives To ... -
Fetal head descent assessed by transabdominal ultrasound: a prospective observational study
(Peer reviewed; Journal article, 2021)Background Detection of copy number variation (CNV) in genes associated with disease is important in genetic diagnostics, and next generation sequencing (NGS) technology provides data that can be used for CNV detection. ... -
Fetal HLA-G mediated immune tolerance and interferon response in preeclampsia
(Peer reviewed; Journal article, 2020)Background Fetal immune tolerance is crucial for pregnancy success. We studied the link between preeclampsia, a severe pregnancy disorder with uncertain pathogenesis, and fetal human leukocyte antigen G (HLA-G) and other ... -
Fetal molding examined with transperineal ultrasound and associations with position and delivery mode
(Journal article; Peer reviewed, 2020)Background To accommodate passage through the birth canal, the fetal skull is compressed and reshaped, a phenomenon known as molding. The fetal skull bones are separated by membranous sutures that facilitate compression ... -
FGD5 amplification in breast cancer patients is associated with tumor proliferation and a poorer prognosis
(Journal article; Peer reviewed, 2017)Purpose Proliferation is a hallmark of cancer. Using a combined genomic approach, FGD5 amplification has been identified as a driver of proliferation in Luminal breast cancer. We aimed to describe FGD5 copy number change ... -
Ficolins do not alter host immune responses to lipopolysaccharide-induced inflammation in vivo
(Journal article; Peer reviewed, 2017)Ficolins are a family of pattern recognition molecules that are capable of activating the lectin pathway of complement. A limited number of reports have demonstrated a protective role of ficolins in animal models of ... -
Finding gene regulatory network candidates using the gene expression knowledge base
(Journal article; Peer reviewed, 2014)Background: Network-based approaches for the analysis of large-scale genomics data have become well established. Biological networks provide a knowledge scaffold against which the patterns and dynamics of ?omics? data can ... -
Fine needle aspirates of kidneys: A promising tool for RNA sequencing in native and transplanted kidneys
(Journal article; Peer reviewed, 2018)Background Transcriptome analysis is emerging as emerging as a promising tool to enhance precision of diagnosis and monitoring in solid organ transplantation. Clinical progress has however been hampered by the current ... -
Fine-mapping the MHC locus in juvenile idiopathic arthritis (JIA) reveals genetic heterogeneity corresponding to distinct adult inflammatory arthritic diseases
(Journal article; Peer reviewed, 2017)Objectives Juvenile idiopathic arthritis (JIA) is a heterogeneous group of diseases, comprising seven categories. Genetic data could potentially be used to help redefine JIA categories and improve the current classification ... -
Finnes det medikamenter som kan forbedre den kognitive funksjonen hos friske individer?: En litteraturstudie av potensielt kognisjonsfremmende medikamenter
(Master thesis, 2010)Bakgrunn. Det er stor faglig og kommersiell interesse rundt medikamenter som kan virke kognisjonsfremmende hos friske individer. Det finnes flere medikamenter som i dag brukes i behandling av ulike sykdomstilstander, og ... -
The first mitochondrial 5-methylcytosine map in a non-model teleost (Oreochromis niloticus) reveals extensive strand-specific and non-CpG methylation
(Peer reviewed; Journal article, 2021)DNA methylation is one of the main epigenetic mechanisms that regulate gene expression in a manner that depends on the genomic context and varies considerably across taxa. This DNA modification was first found in nuclear ... -
The first mitochondrial 5-methylcytosine map in a non-model teleost (Oreochromis niloticus) reveals extensive strand-specific and non-CpG methylation
(Journal article; Peer reviewed, 2021)DNA methylation is one of the main epigenetic mechanisms that regulate gene expression in a manner that depends on the genomic context and varies considerably across taxa. This DNA modification was first found in nuclear ... -
First Trimester Urine and Serum Metabolomics for Prediction of Preeclampsia and Gestational Hypertension: A Prospective Screening Study
(Journal article; Peer reviewed, 2015)Hypertensive disorders of pregnancy, including preeclampsia, are major contributors to maternal morbidity. The goal of this study was to evaluate the potential of metabolomics to predict preeclampsia and gestational ... -
"Five-year changes in population newborn health associated with new preventive services in targeted risk-group pregnancies"
(Journal article; Peer reviewed, 2019)Backgrounds: In 2009, the prevention service “Familieambulatoriet” (FA) was established in three pilot hospital areas offering psychosocial support and health monitoring to parents in high risk regarding mental health and ... -
FKBP12 is a major regulator of ALK2 activity in multiple myeloma cells
(Journal article; Peer reviewed, 2023)Background: The immunophilin FKBP12 binds to TGF-β family type I receptors, including the BMP type I receptor ALK2. FKBP12 keeps the type I receptor in an inactive state and controls signaling activity. Removal of FKBP12 ... -
Flow analysis of RANK expression on myeloid cells and identification of bone marrow cells expressing IL-32 in multiple myeloma patients
(Master thesis, 2016)Multiple myeloma is the second most common hematological cancer worldwide, characterized by an increased expansion of malignant plasma cells in the bone marrow, organ dysfunction, immunodeficiency and bone erosion. Nearly ...